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Table 16 Effect of DAS-77 on antioxidant enzymes in rat brain in the reversibility study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Reversibility study
   GSH (nm/mg) SOD (u/mg) CAT (u/mg) Peroxidase (u/mg) MDA (nm/mg) Protein (mg)
Distilled water (10 ml/kg) 3.67 ± 0.70 5.36 ± 0.91 24.72 ± 4.20 1.68 ± 0.29 0.25 ± 0.04 16.76 ± 0.94
DAS-77 80 2.49 ± 0.41 4.36 ± 0.40 20.12 ± 1.86 1.37 ± 0.13 0.28 ± 0.04 16.69 ± 1.20
DAS-77 400 2.15 ± 0.27 3.53 ± 0.33 16.29 ± 1.55 1.11 ± 0.11 0.33 ± 0.04 20.28 ± 1.22
DAS-77 2000 3.35 ± 1.20 5.26 ± 1.62 24.26 ± 7.49 1.65 ± 0.51 0.27 ± 0.04 20.76 ± 2.90
  1. Values are mean ± S.E.M. (n = 4). p > 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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