From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | |||||
---|---|---|---|---|---|---|---|
Ā | Ā | GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) |
Distilled water | (10 ml/kg) | 3.67āĀ±ā0.70 | 5.36āĀ±ā0.91 | 24.72āĀ±ā4.20 | 1.68āĀ±ā0.29 | 0.25āĀ±ā0.04 | 16.76āĀ±ā0.94 |
DAS-77 | 80 | 2.49āĀ±ā0.41 | 4.36āĀ±ā0.40 | 20.12āĀ±ā1.86 | 1.37āĀ±ā0.13 | 0.28āĀ±ā0.04 | 16.69āĀ±ā1.20 |
DAS-77 | 400 | 2.15āĀ±ā0.27 | 3.53āĀ±ā0.33 | 16.29āĀ±ā1.55 | 1.11āĀ±ā0.11 | 0.33āĀ±ā0.04 | 20.28āĀ±ā1.22 |
DAS-77 | 2000 | 3.35āĀ±ā1.20 | 5.26āĀ±ā1.62 | 24.26āĀ±ā7.49 | 1.65āĀ±ā0.51 | 0.27āĀ±ā0.04 | 20.76āĀ±ā2.90 |