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Table 4 Serum biochemical values following 13 weeks of daily oral administration of NS in male and female rats

From: Assessment of anti-depressant effect of nelumbinis semen on rats under chronic mild stress and its subchronic oral toxicity in rats and beagle dogs

Serum Chemistry Values
Dose (mg/kg) Sex AST ALT ALP BUN CRE GLU CHO PRO CPK ALB
  (IU/L) (IU/L) (IU/L) (mg/dl) (mg/dl) (mg/dl) (mg/dl) (g/dl) (IU/L) (g/dl)
0 M 83.3 ± 15.0 40.4 ± 9.0 83.2 ± 14.2 16.2 ± 1.6 0.5 ± 0.1 132.2 ± 14.1 113.1 ± 15.7 6.2 ± 0.2 211.3 ± 129 3.0 ± 0.1
  F 85.7 ± 12.5 33.6 ± 7.8 74.3 ± 18.6 15.1 ± 1.3 0.6 ± 0.0 108.2 ± 6.9 95.2 ± 18.5 6.0 ± 0.4 186.8 ± 72.0 3.1 ± 0.2
500 M 80.0 ± 12.1 42.2 ± 5.4 90.6 ± 23.6 16.2 ± 3.0 0.5 ± 0.1 123.6 ± 12.1 108.0 ± 18.2 6.1 ± 0.1 173.1 ± 86.8 2.95 ± .01
  F 92.9 ± 13.1 33.4 ± 3.9 69.8 ± 12.4 16.4 ± 3.0 0.6 ± 0.1 114.4 ± 7.5 90.1 ± 12.8 6.1 ± 0.2 173.6 ± 74.8 3.1 ± 0.1
1000 M 84.1 ± 17.1 40.9 ± 6.1 92.1 ± 18.8 15.4 ± 1.6 0.5 ± 0.1 131.1 ± 17.0 103.1 ± 21.7 6.1 ± 0.2 157.8 ± 97.1 3.0 ± 0.1
  F 96.0 ± 21.0 35.0 ± 7.0 69.3 ± 16.9 16.0 ± 2.3 0.6 ± 0.1 107.5 ± 9.6 96.9 ± 20.3 6.2 ± 0.3 173.4 ± 87.4 3.2 ± 0.2
2000 M 83.1 ± 19.3 44.2 ± 12.4 84.0 ± 13.7 16.9 ± 3.6 0.5 ± 0.0 133.6 ± 12.6 111.4 ± 27.3 6.3 ± 0.1 122.3 ± 65.2 3.0 ± 0.1
  F 98.8 ± 22.5 35.8 ± 4.6 77.6 ± 14.2 16.4 ± 2.0 0.6 ± 0.1 112.8 ± 10.3 90.0 ± 20.1 6.0 ± 0.4 141.0 ± 61.2 3.1 ± 0.1
  1. ALB = Albumin, ALP = Alkaline phosphatase, ALT = Alanine aminotransferase, AST = Aspartate aminotransferase, BUN = Blood urea nitrogen, CHO = Total cholesterol, CPK = Creatine phosphokinase, CRE = Creatinine, GLU = Glucose, PRO = Total protein.