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Table 3 Hematological values following 13 weeks of daily oral administration of NS in male and female rats

From: Assessment of anti-depressant effect of nelumbinis semen on rats under chronic mild stress and its subchronic oral toxicity in rats and beagle dogs

Hematology values
Dose (mg/kg) Sex WBC RBC HGB HCT MCV MCH MCHC RDW HDW PLT
   (103/μl) (106/μl) (g/dl) (%) (fl) (pg) (g/μl) (%) (g/dl) (103/μl)
0 M 9.1 ± 1.1 9.2 ± 0.3 16.1 ± 0.5 51.3 ± 1.6 56.1 ± 1.3 17.6 ± 0.5 31.4 ± 0.4 12.0 ± 0.3 2.1 ± 0.1 1140 ± 98
  F 4.9 ± 1.6 7.8 ± 0.3 14.6 ± 0.4 47.0 ± 1.3 60.3 ± 1.1 18.7 ± 0.6 31.0 ± 0.7 10.8 ± 0.2 1.9 ± 0.1 1147 ± 106
500 M 8.2 ± 1.5 9.0 ± 0.2 16.0 ± 0.4 51.5 ± 0.9 57.2 ± 1.3 17.9 ± 0.5 31.2 ± 0.5 12.3 ± 0.2 * 2.25 ± 0.1 ** 1066 ± 115
  F 4.7 ± 1.6 7.9 ± 0.2 14.5 ± 0.4 47.1 ± 1.3 59.4 ± 0.6 18.3 ± 0.4 30.8 ± 0.6 10.8 ± 0.4 2.0 ± 0.2 1111 ± 64
1000 M 9.1 ± 1.4 8.9 ± 0.3 15.8 ± 0.7 50.7 ± 1.7 56.7 ± 1.0 17.7 ± 0.5 31.3 ± 0.4 12.3 ± 0.4 2.2 ± 0.1 * 1121 ± 45
  F 4.2 ± 2.1 7.9 ± 0.2 14.6 ± 0.3 47.4 ± 1.1 60.4 ± 1.7 18.5 ± 0.6 30.7 ± 0.3 10.9 ± 0.4 1.9 ± 0.2 1081 ± 77
2000 M 9.3 ± 2.1 9.3 ± 0.4 16.0 ± 0.5 51.6 ± 1.8 55.7 ± 2.0 17.3 ± 0.7 31.0 ± 0.4 12.4 ± 0.4 * 2.2 ± 0.1 ** 1177 ± 143
  F 4.8 ± 1.8 7.7 ± 0.3 14.4 ± 0.5 17.0 ± 1.4 60.8 ± 1.0 18.6 ± 0.3 30.6 ± 0.3 10.8 ± 0.4 2.0 ± 0.2 1063 ± 113
  1. HCT = Hematocrit, HDW = Hb conc. Distribution width, HGB = Hemoglobin concentration, MCH = Mean corpuscular hemoglobin, MCHC = Mean corpuscular hemoglobin concentration, MCV = Mean corpuscular volume, PLT = Platelet, RBC = Red blood cell, RDW = Red cell distribution width, WBC = White blood cell.
  2. *P < 0.05, **P < 0.01 compared to the control group.