Table 4 Serum biochemical values of animals treated with SST for 4 weeks
Dose (mg/kg/day) | 0 | 500 | 1000 | 2000 |
|---|---|---|---|---|
Male rat | ||||
Glucose (mg/dL) | 120.0 ± 14.95 | 131.6 ± 18.66 | 133.8 ± 24.86 | 122.4 ± 6.90 |
BUN (mg/dL) | 14.0 ± 1.58 | 13.5 ± 1.09 | 12.9 ± 1.90 | 12.9 ± 1.60 |
Creatinine (mg/dL) | 0.57 ± 0.05 | 0.55 ± 0.05 | 0.55 ± 0.03 | 0.58 ± 0.04 |
Total protein (g/dL) | 6.42 ± 0.13 | 6.54 ± 0.17 | 6.19 ± 0.29 | 6.48 ± 0.20 |
Albumin (g/dL) | 4.08 ± 0.06 | 4.12 ± 0.12 | 3.99 ± 0.09 | 4.09 ± 0.09 |
Albumin/globulin ratio | 1.75 ± 0.11 | 1.70 ± 0.08 | 1.83 ± 0.15 | 1.71 ± 0.05 |
Total cholesterol (mg/dL) | 52.0 ± 7.75 | 57.0 ± 8.51 | 57.6 ± 18.77 | 50.8 ± 6.42 |
Triglycerides (mg/dL) | 32.1 ± 9.98 | 31.4 ± 9.83 | 36.5 ± 8.41 | 36.0 ± 9.96 |
Phospholipid (mg/dL) | 86 ± 10.0 | 90 ± 5.1 | 87 ± 19.6 | 87 ± 11.3 |
AST (IU/L) | 136.1 ± 20.74 | 152.0 ± 33.87 | 119.8 ± 14.15 | 157.6 ± 32.13 |
ALT (IU/L) | 28.4 ± 2.67 | 36.2 ± 11.11 | 30.5 ± 3.22 | 32.7 ± 2.25 |
Total bilirubin (mg/dL) | 0.13 ± 0.010 | 0.13 ± 0.004 | 0.12 ± 0.015 | 0.113 ± 0.015 |
ALP (IU/L) | 590.0 ± 84.05 | 506.1 ± 104.95 | 521.4 ± 94.21 | 557 ± 52.56 |
Creatine kinase (IU/L) | 872 ± 275 | 935 ± 321 | 759 ± 156 | 989 ± 327 |
Female | ||||
Glucose (mg/dL) | 100.3 ± 28.10 | 89.1 ± 18.43 | 98.9 ± 10.13 | 108.1 ± 18.59 |
BUN (mg/dL) | 18.7 ± 1.87 | 17.7 ± 1.89 | 15.6 ± 2.22 | 15.3 ± 2.26 |
Creatinine (mg/dL) | 0.62 ± 0.05 | 0.65 ± 0.05 | 0.58 ± 0.07 | 0.60 ± 0.03 |
Total protein (g/dL) | 6.96 ± 0.11 | 6.94 ± 0.16 | 6.79 ± 0.14 | 6.98 ± 0.21 |
Albumin (g/dL) | 4.47 ± 0.15 | 4.45 ± 0.09 | 4.34 ± 0.04 | 4.48 ± 0.10 |
Albumin/globulin ratio | 1.79 ± 0.11 | 1.79 ± 0.08 | 1.78 ± 0.07 | 1.80 ± 0.13 |
Total cholesterol (mg/dL) | 73.2 ± 14.96 | 65.6 ± 8.23 | 60.2 ± 7.36 | 56.0 ± 17.18 |
Triglycerides (mg/dL) | 27.3 ± 3.67 | 25.6 ± 1.54 | 29.1 ± 7.61 | 25.2 ± 5.98 |
Phospholipid (mg/dL) | 124 ± 19.4 | 111 ± 9.8 | 106 ± 11.6 | 104 ± 21.5 |
ASP (IU/L) | 160.3 ± 25.73 | 142.6 ± 9.32 | 155.9 ± 27.99 | 140.9 ± 33.54 |
ALT (IU/L) | 25.7 ± 2.47 | 30.0 ± 5.14 | 25.3 ± 3.46 | 26.7 ± 4.66 |
Total bilirubin (mg/dL) | 0.13 ± 0.014 | 0.13 ± 0.014 | 0.12 ± 0.011 | 0.13 ± 0.010 |
ALP (IU/L) | 413.6 ± 61.29 | 432.5 ± 86.29 | 379.4 ± 40.70 | 383.6 ± 103.75 |
Creatine kinase (IU/L) | 1127 ± 288 | 966 ± 196 | 1044 ± 263 | 947 ± 411 |