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Table 2 Effects of Bersama engleriana on body weight, relative weights of liver and pancreas and, lipid profile on nicotinamide/streptozotocin-induced diabetic rats

From: Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats

Groups Body weight(g) Relative organ weight (mg/g) Lipid profile(mg/dl)
  Initial Final % variation Liver Pancreas TC LDL-C HDL-C TG
Control 210.06 ± 11.25 251.00 ± 10.57 19.48 33.86 ± 01.07 4.11 ± 0.50 98.06 ± 05.54 45.37 ± 03.93 36.15 ± 02.50 82.70 ± 05.81
Untreated diabetic 210.53 ± 12.36 203.00 ± 04.52 -3.57 11.23 ± 0.70*** 1.37 ± 0.08*** 153.53 ± 17.82* 118.8 3± 12.82* 12.44 ± 03.65* 96.39 ± 15.83
Diabetic + Glibenclamide (0.25 mg/kg) 217.88 ± 22.06 250.50 ± 10.57 14.97 13.46 ± 01.31*** 0.96 ± 0.09*** 134.77 ± 07.58* 88.09 ± 11.14*# 20.42 ± 02.84* 70.60 ± 07.87#
Diabetic + Aqueous extract (300 mg/kg) 250.85 ± 12.06 230.00 ± 06.35 -8.31 14.56 ± 0.69*** 1.23 ± 0.15*** 127.97 ± 02.07 89.27 ± 07.67*# 17.60 ± 02.05* 64.05 ± 09.61*#
Diabetic + Aqueous extract (600 mg/kg) 254.85 ± 15.50 237.33 ± 06.33 -6.87 15.70 ± 01.59*** 1.60 ± 0.21*** 130.62 ± 06.57* 76.12 ± 02.35*## 12.10 ± 01.51* 79.51 ± 11.64#
Diabetic + Methanolic extract (300 mg/kg) 199.41 ± 06.56 224.00 ± 11.69 12.33 15.69 ± 0.55*** 2.42 ± 0.21***## 123.32 ± 12.46 89.48 ± 12.69*# 29.96 ± 07.28# 59.56 ± 11.39***#
Diabetic + Methanolic extract (600 mg/kg) 187.98 ± 09.24 223.67 ± 07.57 19.05 19.23 ±01.19***### 2.41 ± 0.16***## 100.75 ± 14.74# 59.19 ± 08.39### 32.97 ± 04.37# 56.01 ± 09.70***##
  1. Values are means ± SEM; number of animals per group = 6.
  2. *: p<0.05; *** p <0.001: significantly different compared to control.
  3. #: p <0.05; ##: p <0.01; ###: p<0.001 significantly different compared to untreated diabetic.