Group | Dose (mg/kg bw.) | Blood Pressure (mmHg) | |||||
---|---|---|---|---|---|---|---|
 |  | Before induction of hypertension | After induction of hypertension | After treatment of hypertension | |||
 |  | sBP | dBP | sBP | dBP | sBP | dBP |
Normal | - | 118 ± 0.4 | 81 ± 0.3 | 120 ± 0.3 | 82 ± 0.4 | 120 ± 0.3* | 81 ± 0.4* |
Untreated control | - | 119 ± 0.5 | 80 ± 0.4 | 178 ± 0.4 | 128 ± 0.4 | 181 ± 0.6 | 137* ± 0.4 |
Propanolol-treated | 10 | 120 ± 0.6 | 81 ± 0.3 | 177 ± 0.4 | 131 ± 0.5 | 135 ± 0.4* | 95 ± 0.4* |
CUR | 1000 | 119 ± 0.5 | 82 ± 0.3 | 178 ± 0.3 | 130 ± 0.4 | 164 ± 0.4 | 126 ± 0.3 |
 | 3000 | 119 ± 0.4 | 79 ± 0.4 | 180 ± 0.4 | 131 ± 0.5 | 152 ± 0.3 | 121 ± 0.4 |
 | 5000 | 118 ± 0.4 | 78 ± 0.3 | 179 ± 0.4 | 130 ± 0.4 | 136 ± 0.4* | 101 ± 0.4* |
ZO | 1000 | 119 ± 0.5 | 81 ± 0.3 | 178 ± 0.5 | 130 ± 0.5 | 168 ± 0.3 | 119 ± 0.3 |
 | 3000 | 120 ± 0.5 | 80 ± 0.3 | 180 ± 0.4 | 129 ± 0.5 | 163 ± 0.5 | 120 ± 0.5 |
 | 5000 | 120 ± 0.4 | 81 ± 0.4 | 181 ± 0.5 | 128 ± 0.4 | 162 ± 0.4 | 119 ± 0.4 |
AL | 1000 | 121 ± 0.5 | 79 ± 0.4 | 180 ± 0.4 | 131 ± 0.5 | 155 ± 0.3 | 109 ± 0.4 |
 | 3000 | 118 ± 0.4 | 82 ± 0.4 | 179 ± 0.5 | 126 ± 0.5 | 156 ± 0.4 | 105 ± 0.5 |
 | 5000 | 119 ± 0.3 | 81 ± 0.3 | 177 ± 0.4 | 169 ± 0.4 | 134 ± 0.4* | 98 ± 0.3* |
PC | 100 | 117 ± 0.3 | 79 ± 0.4 | 180 ± 0.4 | 127 ± 0.5 | 180 ± 0.5 | 126 ± 0.4 |
 | 500 | 118 ± 0.4 | 81 ± 0.3 | 177 ± 0.3 | 129 ± 0.4 | 170 ± 0.4 | 122 ± 0.4 |
 | 1000 | 120 ± 0.5 | 80 ± 0.4 | 179 ± 0.4 | 128 ± 0.4 | 139 ± 0.3* | 113 ± 0.4* |
PPF | 1000 | 119 ± 0.4 | 82 ± 0.4 | 179 ± 0.4 | 131 ± 0.4 | 169 ± 0.5 | 117 ± 0.3 |
 | 3000 | 120 ± 0.5 | 79 ± 0.4 | 180 ± 0.5 | 130 ± 3.3 | 162 ± 0.4 | 121 ± 0.4 |
 | 4000 | 119 ± 0.4 | 80 ± 0.3 | 181 ± 0.5 | 128 ± 0.5 | 162 ± 0.4 | 120 ± 0.5 |