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Table 5 Effect of Rutin on assessment of oxidative stress

From: CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

Treatment CAT (U/min) SOD (U/mg protein) GST nM /min/mg protein GSH-Px nM/min/mg protein GSR nM /min/mg protein GSH (μM /g tissue) TBARS (nM /min/mg protein)
Control 4.81±0.10++ 22.71±1.18++ 192.12±2.49++ 84.12±5.19++ 127.23±10.52++ 1.23±0.02++ 28.33±1.12++
3 ml/kg CCl4 2.91±0.06** 11.91±0.38** 104.23±2.14** 46.12±3.62** 62.33±9.28** 0.60±.01** 52.17±2.61**
50 mg/kg Rutin+CCl4 4.60±0.16++ 19.52±0.47++ 175.21±2.19++ 70.23±4.31++ 101.13±9.14++ 1.17±0.04++ 31.17±1.74++
70 mg/kg Rutin+CCl4 5.03±0.09++ 21.41±0.62++ 183.32±3.09++ 80.12±6.82++ 121.12±12.24++ 1.18±0.01++ 27.14±1.22++
  1. Mean ±SE (n=6 number).
  2. ** indicate significance from the control group at P< 0.01 probability level.
  3. ++ indicate significance from the CCl4 group at P< 0.01 probability level.