Skip to main content

Table 3 Effect of FPL extract on pylorus ligation induced gastric ulcers

From: Effect of Flabellaria paniculata Cav. extracts on gastric ulcer in rats

Treatment

Dose (mg/kg)

Ulcer index

% Inhibition

Gastric juice (ml)

Gastric pH

Gastric acidity (mEq/l)

Control (3% Tween 20)

-

1.81 ± 0.5

-

0.95 ± 0.11

2.89 ± 0.28

11.04 ± 1.76

FPL

100

1.19 ± 0.26

34.7

0.72 ± 0.21

2.61 ± 0.41

7.17 ± 0.61

 

200

0.69 ± 0.17

61.9

0.50 ± 0.13*

2.64 ± 0.19

7.30 ± 0.75

 

400

0.37 ± 0.25*

79.6

0.22 ± 0.05*

3.10 ± 0.21

6.30 ± 1.41

Cimetidine

100

0.62 ± 0.42

42.9

0.86 ± 0.18

3.22 ± 0.33

9.6 ± 0.71

  1. The results are mean ± SEM for 5 animals/group. * Significantly different from the control at p < 0.05.