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Table 3 Antidiabetic effects of 80% methanolic leaf extract of Caylusea abyssinica on blood glucose levels in streptozotocin induced mice

From: Evaluation of the effects of 80% methanolic leaf extract of Caylusea abyssinica (fresen.) fisch. & Mey. on glucose handling in normal, glucose loaded and diabetic rodents

  Blood glucose level in mg/dL
Group 0 h 1 h 2 h 3 h 4 h
TW80 376.56 ± 39.02 432. 78 ± 33.87 338.33 ± 24.22 331.45 ± 47.53 272.00 ± 38.58
GL5 342.44 ± 36.97 306.00 ± 40.97 223.78 ± 31.27a1, b1 161.22 ± 27.69a2, b2 126.56 ± 22.64a 3, b2
CA100 335.33 ± 48.12 269.56 ± 43.34b1 215.11 ± 37.27b1 179.89 ± 39.39a1, b1 160.33 ± 36.98a1, b1
CA200 326.44 ± 43.78 268.33 ± 18.28b1 167.89 ± 18.01a3, b2 147. 78 ± 19.61a3, b2 123.00 ± 15.52 a3, b2
CA300 352.11 ± 38.52 318.556 ± 40.49 229.22 ± 30.78b1 187.44 ± 36.39 a2, b1 166.22 ± 34.29a2
  1. n = 9-10; CA100 = C. abyssinica extract 100 mg/kg, CA200 = C. abyssinica extract 200 mg/kg, CA300 = C. abyssinica extract 300 mg/kg, TW80 = 2%Tween-80, GL5 = Glibenclamide 5 mg/kg; a compared with fasting blood glucose level (t = 0 h), b compared with negative control group; 1p < 0.05, 2 p < 0.01, and 3p < 0.001.