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Table 3 Antidiabetic effects of 80% methanolic leaf extract of Caylusea abyssinica on blood glucose levels in streptozotocin induced mice

From: Evaluation of the effects of 80% methanolic leaf extract of Caylusea abyssinica (fresen.) fisch. & Mey. on glucose handling in normal, glucose loaded and diabetic rodents

 

Blood glucose level in mg/dL

Group

0 h

1 h

2 h

3 h

4 h

TW80

376.56 ± 39.02

432. 78 ± 33.87

338.33 ± 24.22

331.45 ± 47.53

272.00 ± 38.58

GL5

342.44 ± 36.97

306.00 ± 40.97

223.78 ± 31.27a1, b1

161.22 ± 27.69a2, b2

126.56 ± 22.64a 3, b2

CA100

335.33 ± 48.12

269.56 ± 43.34b1

215.11 ± 37.27b1

179.89 ± 39.39a1, b1

160.33 ± 36.98a1, b1

CA200

326.44 ± 43.78

268.33 ± 18.28b1

167.89 ± 18.01a3, b2

147. 78 ± 19.61a3, b2

123.00 ± 15.52 a3, b2

CA300

352.11 ± 38.52

318.556 ± 40.49

229.22 ± 30.78b1

187.44 ± 36.39 a2, b1

166.22 ± 34.29a2

  1. n = 9-10; CA100 = C. abyssinica extract 100 mg/kg, CA200 = C. abyssinica extract 200 mg/kg, CA300 = C. abyssinica extract 300 mg/kg, TW80 = 2%Tween-80, GL5 = Glibenclamide 5 mg/kg; a compared with fasting blood glucose level (t = 0 h), b compared with negative control group; 1p < 0.05, 2 p < 0.01, and 3p < 0.001.