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Table 2 Genotoxic activity of cactus cladode extract and CDDP by the SOS chromotest in the presence of E.coli PQ37

From: Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

Extract β-gal (U) AP (U) IF
NC 0,65 ± 0,001 1,9 ± 0,001  
AFB1 9,21 ± 0,005 2,5 ± 0,003 4,24
CDDP 1,98 ± 0,004 2,5 ± 0,002 3,24
CCE 1,1 ± 0,002 1,7 ± 0,001 0,73
CDDP + CCE 1,56 ± 0,002 1,25 ± 0,002 1,35
  1. β-gal β-galactosidase, AP alkaline phosphatase, U enzyme units, IF induction factor, NC negative control (non treated cells). AFB1 aflatoxin B1. (Positive control of genotoxicity).
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