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Table 2 Genotoxic activity of cactus cladode extract and CDDP by the SOS chromotest in the presence of E.coli PQ37

From: Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

Extract

β-gal (U)

AP (U)

IF

NC

0,65 ± 0,001

1,9 ± 0,001

 

AFB1

9,21 ± 0,005

2,5 ± 0,003

4,24

CDDP

1,98 ± 0,004

2,5 ± 0,002

3,24

CCE

1,1 ± 0,002

1,7 ± 0,001

0,73

CDDP + CCE

1,56 ± 0,002

1,25 ± 0,002

1,35

  1. β-gal β-galactosidase, AP alkaline phosphatase, U enzyme units, IF induction factor, NC negative control (non treated cells). AFB1 aflatoxin B1. (Positive control of genotoxicity).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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