Figure 4From: Whole plant based treatment of hypercholesterolemia with Crataegus laevigata in a zebrafish model Hawthorn leaves and flowers (HLF) interact with cholesterol (CH) to impact cardiac output (CO). A. HLF show significant interaction with CH in their influence on CO. CH decreases CO within 0% HLF and CH decreases CO when comparing all 0% CH-treated to all 8% CH-treated fish B. No interaction effect was observed on stroke volume (SV). CH decreases SV within 0% HLF and CH decreases SV when comparing all 0% CH-treated to all 8% CH-treated fish C. No interaction effect was observed on heart rate (HR). CH decreases HR when comparing all 0% CH-treated to all 8% CH-treated fish. * P < 0.05, bars are mean + S.D. 2-way ANOVA with Holm-Sidak post-hoc analysis. n = 12-19 per group.Back to article page