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Figure 3 | BMC Complementary and Alternative Medicine

Figure 3

From: Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster

Figure 3

Effects of PA on the activities of histone demethylases. (A) Effects of PA, apocynin or 2,4-PDCA on histone demethylase JMJD2A activity. IC50 values are mean ± SEM of three separate experiments. (B) Effects of PA, apocynin or 2,4-PDCA on histone demethylase JMJD2B activity. IC50 values are mean ± SEM of three separate experiments. (C) Effects of PA, apocynin or 2,4-PDCA on histone demethylase JMJD2C activity. IC50 values are mean ± SEM of three separate experiments. (D) Effects of PA or apocynin on the activities of lysine-specific demethylase LSD1, histone deacetylase HDAC1 and HDAC8. Values are mean ± SEM (n = 4). Data are expressed as a percentage of the control value in each experiment.

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