Antimicrobial and toxicological activities of five medicinal plant species from Cameroon Traditional Medicine

Table 2 Inhibition zone diameters (ID in mm) and minimal inhibitory concentration (MIC in mg/ml) of hexanic, ethylacetate and methanolic extracts of five medicinal plants against Gram – bacteria species

Plant material	Extracts	Proteus mirabilis		Escherichia coli		Shigella flexneri		Pseudomonas aeruginosa		Klebsiella pneumoniae		Salmonella typhi
		ID	MIC	ID	MIC	ID	MIC	ID	MIC	ID	MIC	ID	MIC
*Piptadeniastum africana*	Hexane	8	>20	0	>20	0	>20	10	20	10	>20	0	>20
	EtOAc	8	10	20	2.50	17	1.21	18	1.25	12	5	19	0.62
	MeOH	14	2.5	22	1.25	21	1.21	26	0.31	19	2.5	26	1.25
*Cissus aralioides*	Hexane	10	>20	11	>20	10	>20	12	20	10	>20	9	>20
	EtOAc	10	5	21	2.50	19	5	27	0.31	18	5	28	0.05
	MeOH	9	10	9	10	10	1.25	12	0.62	8	2.5	13	0.62
*Hileria latifolia*	Hexane	10	20	10	20	10	20	12	20	10	20	10	20
	EtOAc	15	1.25	15	1.25	15	1.25	25	0.62	15	2.50	24	0.62
	MeOH	13	1.25	19	1.25	18	1.25	26	0.62	16	2.50	24	0.62
*Phyllanthus muellerianus*	Hexane	10	10	10	20	13	20	14	10	10	10	13	10
	EtOAc	16	1.25	24	0.62	22	1.25	28	0.31	18	1.25	29	0.31
	MeOH	24	1.25	26	0.31	25	0.62	33	0.07	22	1.25	30	0.15
*Gladiolus gregasius*	Hexane	12	>20	11	>20	15	20	13	20	14	20	10	10
	EtOAc	10	10	12	10	14	20	13	10	12	10	13	5
	MeOH	0	>20	9	20	0	>20	0	>20	0	>20	12	10
Reference Drugs*		14	0.12	16	0.12	17	0.03	15	0.06	15	0.06	22	0.06

*Gentamycin was used as reference drug for bacteria species. ID: Inhibition zone diameters in mm; MIC: and minimal inhibition concentration. Note: Extracts and reference drugs were tested at the concentration of 50 mg/ml and 0.2 mg/ml respectively for the determination of IDs

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