Figure 6

Effect of SR10 on PDGF-BB-induced migration of A7r5 cells in a transwell migration assay. A7r5 cells were loaded in the upper chamber while PDGF-BB (25 ng/ml) was loaded in the lower chamber in the absence or presence of various concentrations of SR10. After 3-hour incubation, migrated cells were observed in the lower surface of the membrane (A). Number of migrated cells was counted for five regions per filter. Data were expressed as mean ± S.D. with three replicates in each of three independent trials. By Mann-Whitney test, significant difference when compared to PDGF-BB alone was indicated by *p < 0.05 or # p < 0.01 (B).