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Table 2 Antibiofilm effect of thymoquinone against four positive biofilm strains

From: Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation

Strains Inhibition of biofilm development (%)
  Crystal Violet assay XTT assay
  aBIC50 (µg/ml) bBIC90 (µg/ml) BIC50 (µg/ml) BIC90 (µg/ml)
Enterococcus faecalis ATCC 29212 85 349 44 145
Staphylococcus aureus ATCC 25923 22 75 20.5 51
Staphylococcus epidermidis CIP 106510 60 109 40 90
Pseudomonas aeruginosa ATCC 27853 >512 >512 >512 >512
  1. a, minimum biofilm inhibition concentration of TQ that showed 50% inhibition on the biofilm formation.
  2. b, minimum biofilm inhibition concentration of TQ that showed 90% inhibition on the biofilm formation.