Microphotographs of different experimental groups showing the histopathology of renal tissues. (A) Normal structure of glomerulus, Bowman capsule (BC), proximal tubules (PT) and distal tubules (DT). (B) Alterations induced with gentamicin (100 mg/kg bw) in renal tissues; congested proximal tubules (PTC), leucocytes infiltration (LI). (C) Degeneration of bowman capsule and glomerulus (DBC), tubular necrosis (NT) with gentamicin nephrotoxicity. (D) Gentamicin induced leucocyte infiltration in medullary region (LI). (E) Regeneration of tubules (RT) and mild leucocyte infiltration (LI) with SAME (100 mg/kg bw) in combination with gentamicin. (F) normal architecture of proximal tubule (PT) and distal tubule (DT) with SAME (200 mg/kg bw) along with gentamicin.