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Table 1 Study population characteristics by estrogenic botanical supplement (EBS) use

From: Estrogenic botanical supplements, health-related quality of life, fatigue, and hormone-related symptoms in breast cancer survivors: a HEAL study report

  No. non-EBS users (%) No. EBS users (%) P valuea
  N = 464 N = 303  
Study site    0.12
   Western Washington 90 (19.4) 70 (23.1)  
   New Mexico 259 (55.8) 146 (48.2)  
   Los Angeles County 115 (24.8) 87 (28.7)  
Race    0.63
   Non-Hispanic white 281 (60.6) 173 (57.1)  
   African-American 115 (24.8) 88 (29.0)  
   Hispanic 53 (11.4) 33 (10.9)  
   Others 15 (3.2) 9 (3.0)  
Education    < 0.0001
   ≤ High school 143 (30.8) 51 (16.8)  
   Technical school or some college 154 (33.2) 126 (41.6)  
   College graduate 167 (36.0) 126 (41.6)  
Mean age at diagnosis (SDb), years 56.0 (10.6) 52.5 (8.7) < 0.0001 c
Stage at diagnosis    0.41
   In situ 110 (23.7) 60 (19.8)  
   Localized 257 (55.4) 173 (57.1)  
   Regional 97 (20.9) 70 (23.1)  
Breast cancer treatment    0.43
   No radiation and no chemotherapy 155 (33.4) 86 (28.4)  
   Radiation only 171 (36.9) 116 (38.3)  
   Chemotherapy only 45 (9.7) 29 (9.6)  
   Radiation and chemotherapy 93 (20.0) 72 (23.8)  
Tamoxifen use    0.24
   No 248 (53.5) 175 (57.8)  
   Yes 216 (46.6) 128 (42.2)  
Medical comorbidity    0.007
   None 332 (71.6) 243 (80.2)  
   1 or more condition(s) 132 (28.5) 60 (19.8)  
Activity level within the past year of 30-month interview from sports/recreation (MET hours/week)    < 0.0001
   0 93 (20.0) 33 (10.9)  
   0.1-8.9 201 (43.3) 115 (38.0)  
   ≥ 9 170 (36.6) 155 (51.2)  
Menopausal status at 30-month interview    0.01
   Premenopausal 74 (16.0) 68 (22.4)  
   Postmenopausal    
Never HTd after diagnosis 193 (41.6) 135 (44.6)  
Ever HTd after diagnosis 172 (37.1) 80 (26.4)  
   Unknown 25 (5.4) 20 (6.6)  
Body mass index at 30-month interview (kg/m2)    0.13
   < 25 180 (38.8) 128 (42.2)  
   25-29 133 (28.7) 97 (32.0)  
   ≥ 30 151 (32.5) 78 (25.7)  
Mean isoflavones from soy-containing foods (SDb), mg/day 1.9 (9.4) 4.0 (9.9) 0.002 c
  1. a P-value ascertained from Pearson χ2 test, except where otherwise noted. bSD, standard deviation. c P-value from t test. dHT, hormone therapy.