Suppression of tumor progression by administration of abalone visceral extract. Balb/c female mice were orally administered with abalone visceral extract (100 ul of 50 mg/ml) for 2 weeks before cancer transplantation. Mouse breast cancer model was induced by injection of 4T1 cell (1 × 106 cells) into flank backs. Abalone visceral extract or PBS as control was daily treated by oral administration for 25 days post tumor induction. (A) Picture of tumor from each group was taken. (B) During the treatment period, tumor size was measured every 2 days and shown in graph. (C) After 25 days from post-tumor induction, mice from each group were scarified and the weight of tumor mass was measured. Error bars indicated SE. Data are representative of five independent experiments. One (*), two (**) or three asterisks (***) indicate p < 0.05, p < 0.01 or p < 0.001, respectively.