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Table 3 MIC and IC50 values of active plant extracts with respect to M. smegmatis and clinically-relevant bacterial species.

From: Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis

Plant Part   M. smegmatis   M. bovis   M. tuberculosis   S. aureus
    mg/ml   mg/ml   mg/ml   mg/ml
    MIC IC50   MIC IC50   MIC IC50   MIC IC50
L. novae-zelandiae Bark   0.04 0.02 ± 0.01   1.50 0.54 ± 0.03   4.16 2.39 ± 0.33   > 10 > 10
  Cambium   0.50 0.25 ± 0.01   2.50 1.63 ± 0.21   3.75 1.86 ± 0.22   > 10 > 10
L. bullata Leaf   1.00 0.31 ± 0.15   3.12 2.59 ± 0.43   6.51 5.59 ± 0.32   > 10 > 10
M. excelsa Leaf   0.63 0.11 ± 0.06   8.35 6.95 ± 3.07   > 10 4.83 ± 0.43   2.20 1.17 ± 0.39
  Flower   0.63 0.41 ± 0.06   3.13 1.12 ± 0.12   4.18 2.19 ± 0.76   > 10 > 10
M. laetum Leaf   0.63 0.34 ± 0.02   > 10 > 10   > 10 > 10   > 10 > 10
P. tenuifolium Leaf   2.00 0.78 ± 0.34   > 10 5.37 ± 1.35   1.25 0.51 ± 0.11   > 10 > 10
P. crassifolius Leaf   0.63 0.31 ± 0.01   6.25 4.08 ± 1.76   3.58 1.74 ± 0.18   > 10 > 10
  1. MIC, minimum inhibitory concentration. IC50, 50% inhibitory concentration.