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Table 3 MIC and IC50 values of active plant extracts with respect to M. smegmatis and clinically-relevant bacterial species.

From: Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis

Plant

Part

 

M. smegmatis

 

M. bovis

 

M. tuberculosis

 

S. aureus

   

mg/ml

 

mg/ml

 

mg/ml

 

mg/ml

   

MIC

IC50

 

MIC

IC50

 

MIC

IC50

 

MIC

IC50

L. novae-zelandiae

Bark

 

0.04

0.02 ± 0.01

 

1.50

0.54 ± 0.03

 

4.16

2.39 ± 0.33

 

> 10

> 10

 

Cambium

 

0.50

0.25 ± 0.01

 

2.50

1.63 ± 0.21

 

3.75

1.86 ± 0.22

 

> 10

> 10

L. bullata

Leaf

 

1.00

0.31 ± 0.15

 

3.12

2.59 ± 0.43

 

6.51

5.59 ± 0.32

 

> 10

> 10

M. excelsa

Leaf

 

0.63

0.11 ± 0.06

 

8.35

6.95 ± 3.07

 

> 10

4.83 ± 0.43

 

2.20

1.17 ± 0.39

 

Flower

 

0.63

0.41 ± 0.06

 

3.13

1.12 ± 0.12

 

4.18

2.19 ± 0.76

 

> 10

> 10

M. laetum

Leaf

 

0.63

0.34 ± 0.02

 

> 10

> 10

 

> 10

> 10

 

> 10

> 10

P. tenuifolium

Leaf

 

2.00

0.78 ± 0.34

 

> 10

5.37 ± 1.35

 

1.25

0.51 ± 0.11

 

> 10

> 10

P. crassifolius

Leaf

 

0.63

0.31 ± 0.01

 

6.25

4.08 ± 1.76

 

3.58

1.74 ± 0.18

 

> 10

> 10

  1. MIC, minimum inhibitory concentration. IC50, 50% inhibitory concentration.