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  1. The use of traditional medicine at the primary health care level is widespread and plant-based treatments are being recommended for curing various diseases by traditional medical practitioners all over the wor...

    Authors: Mir Z Gul, Farhan Ahmad, Anand K Kondapi, Insaf A Qureshi and Irfan A Ghazi
    Citation: BMC Complementary and Alternative Medicine 2013 13:53
  2. Metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM) have been associated with insulin-resistance; however, the effective therapies in improving insulin sensitivity are limited. This study is aimed at i...

    Authors: Xiangyu Guo, Hisae Yoshitomi, Ming Gao, Lingling Qin, Ying Duan, Wen Sun, Tunhai Xu, Peifeng Xie, Jingxin Zhou, Liansha Huang and Tonghua Liu
    Citation: BMC Complementary and Alternative Medicine 2013 13:52
  3. Extracts from Polygonum senegalensis (Polygonaceae) and Pseudocedrela kotschyi (Meliaceae) are two important traditionally used medicinal plants in rural Benin to treat many diseases and notably type 2 diabetes. ...

    Authors: Fifa TD Bothon, Eric Debiton, Felicien Avlessi, Christiane Forestier, Jean-Claude Teulade and Dominique KC Sohounhloue
    Citation: BMC Complementary and Alternative Medicine 2013 13:51
  4. Propolis is a honey bee product which contains many active compounds, such as CAPE or chrysin, and has many beneficial activities. Recently, its anti-tumor properties have been discussed. We have tested whethe...

    Authors: Renata Markiewicz-Żukowska, Maria H Borawska, Anna Fiedorowicz, Sylwia K Naliwajko, Diana Sawicka and Halina Car
    Citation: BMC Complementary and Alternative Medicine 2013 13:50
  5. Exposure to ultraviolet (UV) radiation causes various forms of acute and chronic skin damage, including immunosuppression, inflammation, premature aging and photodamage. Furthermore, it induces the generation ...

    Authors: Jéssica PS Silveira, Leonardo N Seito, Samara Eberlin, Gustavo C Dieamant, Cecília Nogueira, Maria CV Pereda and Luiz C Di Stasi
    Citation: BMC Complementary and Alternative Medicine 2013 13:49
  6. Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability. Currently, there is inadequate armor...

    Authors: Hamisi M Malebo, Tanja Wenzler, Monical Cal, Sauda M Swaleh, Maurice O Omolo, Ahmed Hassanali, Urs Séquin, Daniel Häussinger, Petur Dalsgaard, Matthias Hamburger, Reto Brun and Isaiah O Ndiege
    Citation: BMC Complementary and Alternative Medicine 2013 13:48
  7. Ganghwaljetongyeum (GHJTY), a complex herbal decoction, is used to treat rheumatoid arthritis. However, the action mechanism of GHJTY is not still unclear on rheumatoid arthritis. In this study, we examined th...

    Authors: Bo-Ram Jeoung, Kyung Dong Lee, Chang-Su Na, Young-Eok Kim, BoA Kim and Young Ran Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:47
  8. Capsaicin, a pungent phytochemical in a variety of red peppers of the genus Capsicum, has shown an anti-proliferative effect on various human cancer cell lines. In contrast, capsaicin has also been considered to ...

    Authors: Chia-Han Lin, Wei-Cheng Lu, Che-Wei Wang, Ya-Chi Chan and Mu-Kuan Chen
    Citation: BMC Complementary and Alternative Medicine 2013 13:46
  9. Morus alba has long been used in traditional Chinese medicine to treat inflammatory diseases; however, the scientific basis for such usage and the mechanism of action are not well understood. This study investig...

    Authors: Yi-Ching Chen, Yin-Jing Tien, Chun-Houh Chen, Francesca N Beltran, Evangeline C Amor, Ran-Juh Wang, Den-Jen Wu, Clément Mettling, Yea-Lih Lin and Wen-Chin Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:45
  10. The high risk of recurrence faced by patients with bladder cancer has necessitated the administration of supplemental intravesical chemotherapy; however, such treatments often result in severe side effects. As...

    Authors: Chi-Chen Lu, Mei-Yi Lin, Syue-Yi Chen, Cheng-Huang Shen, Lih-Geeng Chen, Hsiao-Yen Hsieh, Michael WY Chan and Cheng-Da Hsu
    Citation: BMC Complementary and Alternative Medicine 2013 13:44
  11. The aim of the present study was to evaluate the physicochemical and antioxidant properties of Malaysian monofloral honey samples—acacia, pineapple and borneo honey—and compare them with tualang honey. Acacia ...

    Authors: Mohammed Moniruzzaman, Md Ibrahim Khalil, Siti Amrah Sulaiman and Siew Hua Gan
    Citation: BMC Complementary and Alternative Medicine 2013 13:43
  12. The current treatments for anxiety disorders and depression have multiple adverse effects in addition to a delayed onset of action, which has prompted efforts to find new substances with potential activity in ...

    Authors: Celso A R A Costa, Thaís C Cury, Bruna O Cassettari, Regina K Takahira, Jorge C Flório and Mirtes Costa
    Citation: BMC Complementary and Alternative Medicine 2013 13:42
  13. Boesenbergia rotunda (Roxb.) Schlecht (family zingiberaceae) is a rhizomatous herb that is distributed from north-eastern India to south-east Asia, especially in Indonesia, Thailand and Malaysia. Previous resear...

    Authors: Kuan-Beng Ng, Ahmad Bustamam, Mohd Aspollah Sukari, Siddig Ibrahim Abdelwahab, Syam Mohan, Michael James Christopher Buckle, Behnam Kamalidehghan, Nabilah Muhammad Nadzri, Theebaa Anasamy, A Hamid A Hadi and Heshu Sulaiman Rahman
    Citation: BMC Complementary and Alternative Medicine 2013 13:41
  14. Chewing stick (miswak Salvadora persica L.) is an effective tool for oral hygiene. It possessed various biological properties including significant antibacterial and anti-fungal effects. In the present study, we ...

    Authors: Saleh A Mohamed and Jalaluddin A Khan
    Citation: BMC Complementary and Alternative Medicine 2013 13:40
  15. One vital therapeutic approach for the treatment of type 2 diabetes mellitus is the use of agents that can decrease postprandial hyperglycaemia by inhibiting carbohydrate digesting enzymes. The present study i...

    Authors: Rabyah B Ali, Item J Atangwho, Navneet Kuar, Mariam Ahmad, Roziahanim Mahmud and Mohd Z Asmawi
    Citation: BMC Complementary and Alternative Medicine 2013 13:39
  16. In South Africa, over 6 million people are hypertensive and the burden of disease shows that cardiovascular diseases (CVDs) are the leading cause of death among adults. Although treatments exist, few people co...

    Authors: Gail D Hughes, Oluwaseyi M Aboyade, Bobby L Clark and Thandi R Puoane
    Citation: BMC Complementary and Alternative Medicine 2013 13:38
  17. The available drugs for diabetes, Insulin or Oral hypoglycemic agents have one or more side effects. Search for new antidiabetic drugs with minimal or no side effects from medicinal plants is a challenge accor...

    Authors: Shaik Abdul Nabi, Ramesh Babu Kasetti, Swapna Sirasanagandla, Thandaiah Krishna Tilak, Malaka Venkateshwarulu Jyothi Kumar and Chippada Appa Rao
    Citation: BMC Complementary and Alternative Medicine 2013 13:37
  18. The aim of this research was to determine the intensity and mechanisms of the cytotoxic actions of five extracts isolated from the endemic plant species Helichrysum zivojinii Černjavski & Soška (family Asteraceae...

    Authors: Ivana Z Matić, Ivana Aljančić, Željko Žižak, Vlatka Vajs, Milka Jadranin, Slobodan Milosavljević and Zorica D Juranić
    Citation: BMC Complementary and Alternative Medicine 2013 13:36
  19. Although there is little information available to quantify the use of complementary and alternative medicine (CAM), growing evidence suggests that CAM prevalence among patients seeking infertility treatment is...

    Authors: Sanaa K Bardaweel, Mayadah Shehadeh, Ghadeer ARY Suaifan and Maria-Vanessa Z Kilani
    Citation: BMC Complementary and Alternative Medicine 2013 13:35
  20. Elevated stress can exacerbate cancer symptom severity, and after completion of primary cancer treatments, many individuals continue to have significant distress. Mindfulness-Based Cancer Recovery (MBCR) is an...

    Authors: Kristin A Zernicke, Tavis S Campbell, Michael Speca, Kelley McCabe-Ruff, Steven Flowers, Dale A Dirkse and Linda E Carlson
    Citation: BMC Complementary and Alternative Medicine 2013 13:34
  21. Phyllanthus niruri L. is a well-known hepatoprotective and antiviral medicinal herb. Recently, we identified Corilagin as a major active component with anti-tumor activity in this herbal medicine. Corilagin is a...

    Authors: Luoqi Jia, Hongyan Jin, Jiayi Zhou, Lianghua Chen, Yiling Lu, Yanlin Ming and Yinhua Yu
    Citation: BMC Complementary and Alternative Medicine 2013 13:33
  22. Bixa orellana L. has been traditionally used in Central and South America to treat a number of ailments, including internal inflammation, and in other tropical countries like Malaysia as treatment for gastric ul...

    Authors: Yoke Keong Yong, Zainul Amiruddin Zakaria, Arifah Abdul Kadir, Muhammad Nazrul Somchit, Gwendoline Ee Cheng Lian and Zuraini Ahmad
    Citation: BMC Complementary and Alternative Medicine 2013 13:32
  23. Prunus yedoensis Matsum. is used as traditional medicine—‘Yaeng-Pi’ or ‘Hua-Pi’—in Japan and Korea. However, no studies have examined the pharmacological activities of the P. yedoensis bark. Only the antioxidant...

    Authors: Kyungjin Lee, Inhye Ham, Gabsik Yang, Mihwa Lee, Youngmin Bu, Hocheol Kim and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2013 13:31
  24. Cyclosporin A (CsA) is an immunosuppressive drug widely used in treatment of auto-immune diseases or after organ transplants. However, several side effects are commonly associated with CsA long term intake, so...

    Authors: Karine M Freitas, Juliana C Monteiro, Marcos LM Gomes, Sebastião R Taboga and Heidi Dolder
    Citation: BMC Complementary and Alternative Medicine 2013 13:30
  25. High salinity and temperature combined with presence of heavy metals and low oxygen renders deep-sea anoxic brines of the Red Sea as one of the most extreme environments on Earth. The ability to adapt and surv...

    Authors: Sunil Sagar, Luke Esau, Tyas Hikmawan, Andre Antunes, Karie Holtermann, Ulrich Stingl, Vladimir B Bajic and Mandeep Kaur
    Citation: BMC Complementary and Alternative Medicine 2013 13:29
  26. Cyperus rotundus Linn. (Cyperaceae) is a Tunisian medicinal plant used in folkloric (traditional) medicine to treat stomach disorders and inflammatory diseases. The present study explored the analgesic, anti-inf...

    Authors: Kilani-Jaziri Soumaya, Mhalla Dhekra, Châbane Fadwa, Ghedira Zied, Limem Ilef, Ghedira Kamel and Chekir-Ghedira Leila
    Citation: BMC Complementary and Alternative Medicine 2013 13:28
  27. Previous study showed that the aqueous extract of the stem bark of Cinnamomum zeylanicum possesses antihypertensive and vasodilatory properties. The present work investigates the acute and chronic antihypertensiv...

    Authors: Paulin Nyadjeu, Elvine Pami Nguelefack-Mbuyo, Albert Donatien Atsamo, Telesphore Benoît Nguelefack, Alain Bertrand Dongmo and Albert Kamanyi
    Citation: BMC Complementary and Alternative Medicine 2013 13:27
  28. Many edible plants are used in Cameroon since ancient time to control microbial infections. This study was designed at evaluating the antibacterial activities of the methanol extracts of ten Cameroonian vegeta...

    Authors: Jaurès AK Noumedem, Marius Mihasan, Stephen T Lacmata, Marius Stefan, Jules R Kuiate and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2013 13:26
  29. Thrombus formed in blood vessels lead to atherothrombotic diseases such as myocardial or cerebral infarction. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, th...

    Authors: M Atiar Rahman, Rabeya Sultana, Talha Bin Emran, M Saiful Islam, M Ashiqur Rahman, Joti Sankhar Chakma, Harun-ur Rashid and Chowdhury Mohammad Monirul Hasan
    Citation: BMC Complementary and Alternative Medicine 2013 13:25
  30. A number of bio-active secondary metabolites have been identified and reported for several Hypericum species. Many studies have reported the potential use of the plant extracts against several pathogens. However,...

    Authors: Zyed Rouis, Nabil Abid, Sadok Koudja, Thabet Yangui, Ameur Elaissi, Pier Luigi Cioni, Guido Flamini and Mahjoub Aouni
    Citation: BMC Complementary and Alternative Medicine 2013 13:24
  31. Geopropolis is a type of propolis containing resin, wax, and soil, collected by threatened stingless bee species native to tropical countries and used in folk medicine. However, studies concerning the biologic...

    Authors: Marcos Guilherme da Cunha, Marcelo Franchin, LíviaCâmaradeCarvalho Galvão, AnaLúciaTascaGóis de Ruiz, João Ernesto de Carvalho, Masarahu Ikegaki, Severino Matias de Alencar, Hyun Koo and Pedro Luiz Rosalen
    Citation: BMC Complementary and Alternative Medicine 2013 13:23
  32. This study was designed to determine if electroacupuncture (EA) preconditioning improves tissue outcome and functional outcome following experimentally induced cerebral ischemia in mice. In addition, we invest...

    Authors: Ji Hyun Kim, Kyung Ha Choi, Young Jung Jang, Ha Neui Kim, Sun Sik Bae, Byung Tae Choi and Hwa Kyoung Shin
    Citation: BMC Complementary and Alternative Medicine 2013 13:22
  33. Labisia pumila, locally known as Kacip Fatimah, is a forest-floor plant that has tremendous potential in the herbal industry. It is one of the five herbal plants identified by the government as one of the nation...

    Authors: Ehsan Karimi, Hawa ZE Jaafar and Syahida Ahmad
    Citation: BMC Complementary and Alternative Medicine 2013 13:20
  34. Osteoarthritis (OA) is a degenerative joint disease that results in the destruction of cartilage. Edible Bird’s Nest (EBN) extract contains important components, which can reduce the progression of osteoarthri...

    Authors: Kien-Hui Chua, Ting-Hun Lee, Kamini Nagandran, Nor Hamdan Md Yahaya, Chew-Tin Lee, Eddie Tan Ti Tjih and Ramlan Abdul Aziz
    Citation: BMC Complementary and Alternative Medicine 2013 13:19
  35. Insomnia is a widespread human health problem, but there currently are the limitations of conventional therapies available. Suanzaoren decoction (SZRD) is a well known classic Chinese herbal prescription for i...

    Authors: Cheng-long Xie, Yong Gu, Wen-Wen Wang, Lin Lu, Deng-lei Fu, Ai-ju Liu, Hui-qin Li, Ji-huang Li, Yan Lin, Wen-jie Tang and Guo-qing Zheng
    Citation: BMC Complementary and Alternative Medicine 2013 13:18
  36. In this study, we investigate the effects of microcurrent stimulation on the repair process of xiphoid cartilage in 45-days-old rats.

    Authors: Carla de Campos Ciccone, Denise Cristina Zuzzi, Lia Mara Grosso Neves, Josué Sampaio Mendonça, Paulo Pinto Joazeiro and Marcelo Augusto Marretto Esquisatto
    Citation: BMC Complementary and Alternative Medicine 2013 13:17
  37. There is widespread use of Complementary and Alternative Medicine (CAM) in Ghana, driven by cultural consideration and paradigm to disease causation. Whether there is concurrent use of conventional medicine an...

    Authors: Joel Yarney, Andrew Donkor, Samuel Y Opoku, Lily Yarney, Isaac Agyeman-Duah, Alice C Abakah and Emmanuel Asampong
    Citation: BMC Complementary and Alternative Medicine 2013 13:16
  38. Naturopaths are an increasingly significant part of the healthcare sector in Australia, yet despite their significant role there has been little research on this practitioner group. Currently the naturopathic ...

    Authors: Jon Lee Wardle, Jon Adams, Chi-Wai Lui and Amie Elizabeth Steel
    Citation: BMC Complementary and Alternative Medicine 2013 13:15
  39. Annona dioica St. Hill (Annonacaeae) is a Brazilian plant used in folk medicine for the treatment of several types of rheumatisms and diarrhoea. The focus of this work was to evaluate the in vitro antiproliferat...

    Authors: Anelise S N Formagio, Candida A L Kassuya, Frederico Formagio Neto, Carla R F Volobuff, Edna K K Iriguchi, Maria do C Vieira and Mary Ann Foglio
    Citation: BMC Complementary and Alternative Medicine 2013 13:14
  40. Tulbaghia violacea Harv. (Alliaceae) is used to treat various ailments, including hypertension (HTN) in South Africa. This study aims to evaluate the contributions of muscarinic receptors and changes in plasma a...

    Authors: Ismaila Raji, Pierre Mugabo and Kenechukwu Obikeze
    Citation: BMC Complementary and Alternative Medicine 2013 13:13
  41. The aim of this study, is to investigate the in vitro antioxidant activity, the total phenols content, the flavonoids content and the antiproliferative activity of methanolic extracts of the plants: Krameria erec...

    Authors: Manuel Jiménez-Estrada, Carlos Velázquez-Contreras, Adriana Garibay-Escobar, Davisela Sierras-Canchola, Ricardo Lapizco-Vázquez, Carolina Ortiz-Sandoval, Armando Burgos-Hernández and Ramón Enrique Robles-Zepeda
    Citation: BMC Complementary and Alternative Medicine 2013 13:12
  42. Si-Wu-Tang (SWT), comprising the combination of four herbs, Paeoniae, Angelicae, Chuanxiong and Rehmanniae, is one of the most popular traditional oriental medicines for women’s diseases. In our previous study...

    Authors: Mandy Liu, Jeffery Fan, Steven Wang, Zhijun Wang, Charles Wang, Zhong Zuo, Moses SS Chow, Leming Shi, Zhining Wen and Ying Huang
    Citation: BMC Complementary and Alternative Medicine 2013 13:11
  43. The present study was undertaken to evaluate the antihyperglycemic, antihyperlipidemic and hepatoprotective effect of a traditional unani formulation “Qurs Tabasheer” in streptozotocin (STZ) induced diabetic w...

    Authors: Danish Ahmed, Manju Sharma, Alok Mukerjee, Pramod W Ramteke and Vikas Kumar
    Citation: BMC Complementary Medicine and Therapies 2013 13:10
  44. Thuja orientalis has been traditionally used to treat patients who suffer from baldness and hair loss in East Asia. The present study sought to investigate the hair growth-promoting activity of T. orientalis hot...

    Authors: Nan-nan Zhang, Dong Ki Park and Hye-Jin Park
    Citation: BMC Complementary and Alternative Medicine 2013 13:9
  45. The number of older adults participating in yoga has increased dramatically in recent years; yet, the physical demands associated with yoga performance have not been reported. The primary aim of the Yoga Empow...

    Authors: Man-Ying Wang, Sean S-Y Yu, Rami Hashish, Sachithra D Samarawickrame, Leslie Kazadi, Gail A Greendale and George Salem
    Citation: BMC Complementary and Alternative Medicine 2013 13:8
  46. Inhibition of the proteolytic activity of 26S proteasome, the protein-degrading machine, is now considered a novel and promising approach for cancer therapy. Interestingly, proteasome inhibitors have been demo...

    Authors: Bindu Noolu, Rajanna Ajumeera, Anitha Chauhan, Balakrishna Nagalla, Raghunath Manchala and Ayesha Ismail
    Citation: BMC Complementary and Alternative Medicine 2013 13:7
  47. Resveratrol, a polyphenol from grapes and red wine has many health beneficial effects, including protection against cardiovascular and neurodegenerative diseases and cancer. However, our group and others have ...

    Authors: Linette Castillo-Pichardo, Luis A Cubano and Suranganie Dharmawardhane
    Citation: BMC Complementary and Alternative Medicine 2013 13:6
  48. Ardisia crispa (Myrsinaceae) is used in traditional Malay medicine to treat various ailments associated with inflammation, including rheumatism. The plant’s hexane fraction was previously shown to inhibit severa...

    Authors: Dayang Erna Zulaikha Awang Hamsin, Roslida Abdul Hamid, Latifah Saiful Yazan, Che Norma Mat Taib and Yeong Looi Ting
    Citation: BMC Complementary and Alternative Medicine 2013 13:5
  49. Mondia whitei and Guibourtia tessmannii are used in Cameroon traditional medicine as aphrodisiacs. The present study was undertaken to evaluate the pro-ejaculatory effects of the aqueous and organic solvent extr...

    Authors: Pierre Watcho, Patrick Brice Deeh Defo, Modeste Wankeu-Nya, Miguel Carro-Juarez, Telesphore Benoît Nguelefack and Albert Kamanyi
    Citation: BMC Complementary and Alternative Medicine 2013 13:4