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  1. Inflammatory response in the CNS mediated by microglia cells play an important role in host defense and is implicated in the pathology of neurodegenerative diseases. We investigated the capacity of Entada african...

    Authors: Brice Ayissi Owona, Nico Frederic Njayou, Stefan A Laufer, Hermann J Schluesener and Paul Fewou Moundipa
    Citation: BMC Complementary and Alternative Medicine 2013 13:254
  2. Hericium erinaceus, as a commonly used medicine or food, has attracted much attention due to its health effects when used as a home remedy for some diseases. The aim of this work was to investigate the hypoglyce...

    Authors: Bin Liang, Zhengdong Guo, Fang Xie and Ainong Zhao
    Citation: BMC Complementary and Alternative Medicine 2013 13:253
  3. Zhuyeqing Liquor (ZYQL), a well-known Chinese traditional health liquor, has various biological properties, including anti-oxidant, anti-inflammatory, immunoenhancement and cardiovascular protective effects.

    Authors: Hong-ying Gao, Guo-yu Li, Jian Huang, Ying Han, Fu-zhou Sun, Xiao-wei Du, Li-juan An, Hang-yu Wang and Jin-hui Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:252
  4. Accumulating evidences suggest that aldose reductase (AR) inhibitors and advanced glycation end product (AGE) formation inhibitors may prevent chronic hyperglycemia-induced long-term complication in diabetes. ...

    Authors: Young Sook Kim, Dong Ho Jung, Ik Soo Lee, So-Jin Choi, Song Yi Yu, Sea-Kwang Ku, Myung-Hwa Kim and Jin Sook Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:251
  5. Multidrug resistance (MDR) is a major hurdle for cancer treatment worldwide and accounts for chemotherapy failure in over 90% of patients with metastatic cancer. Evidence of the cytotoxicity of Cameroonian pla...

    Authors: Victor Kuete, Igor K Voukeng, Roger Tsobou, Armelle T Mbaveng, Benjamin Wiench, Veronique P Beng and Thomas Efferth
    Citation: BMC Complementary and Alternative Medicine 2013 13:250
  6. Visceral leishmaniasis is the most serious form of leishmaniasis and can be lethal if left untreated. Currently available treatments for these parasitic diseases are frequently associated to severe side effect...

    Authors: Igor A Rodrigues, Mariana M B Azevedo, Francisco C M Chaves, Humberto R Bizzo, Suzana Corte-Real, Daniela S Alviano, Celuta S Alviano, Maria S S Rosa and Alane B Vermelho
    Citation: BMC Complementary and Alternative Medicine 2013 13:249
  7. The stress of a breast cancer diagnosis and its treatment can produce a variety of psychosocial sequelae including impaired immune responses. Mindfulness Based Stress Reduction (MBSR) is a structured complemen...

    Authors: Elisabeth Kenne Sarenmalm, Lena B Mårtensson, Stig B Holmberg, Bengt A Andersson, Anders Odén and Ingrid Bergh
    Citation: BMC Complementary and Alternative Medicine 2013 13:248
  8. Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. Many patients suffer from IBS that can be difficult to treat, thus complementary therapies which may be effective and have a low...

    Authors: Jae-Woo Park, Byung-Hee Lee and Hyangsook Lee
    Citation: BMC Complementary and Alternative Medicine 2013 13:247
  9. The aims of this study were to evaluate the effect and mechanism of a traditional Chinese medicine formula: Tongxieyaofang (TXYF) on Rats with Post Infectious Irritable Bowel Syndrome (PI-IBS).

    Authors: Xuguang Hu, Xiaojun Zhang, Bin Han and Weijian Bei
    Citation: BMC Complementary and Alternative Medicine 2013 13:246
  10. The growth-inhibiting and morphostructural effects of seven constituents identified in Asarum heterotropoides root on 14 intestinal bacteria were compared with those of the fluoroquinolone antibiotic ciprofloxaci...

    Authors: Haribalan Perumalsamy, Moon Young Jung, Seung Min Hong and Young-Joon Ahn
    Citation: BMC Complementary and Alternative Medicine 2013 13:245
  11. The Lonicera japonica has been used as natural and healthy drink for its anti-inflammatory effect and pleasant odor in China and Taiwan.

    Authors: Jung C Liao, Wen T Chang, Yu H Lan, Mann J Hour and Hong Z Lee
    Citation: BMC Complementary and Alternative Medicine 2013 13:244
  12. Alpinia pahangensis, a wild ginger distributed in the lowlands of Pahang, Malaysia, is used by the locals to treat flatulence. In this study, the antioxidant and cytotoxic activities of the crude aqueous methano...

    Authors: Chung-Weng Phang, Sri Nurestri Abd Malek and Halijah Ibrahim
    Citation: BMC Complementary and Alternative Medicine 2013 13:243
  13. Catechins-rich oil palm (Elaeis guineensis) leaves extract (OPLE) is known to have antioxidant activity. Several polyphenolic compounds reported as antioxidants such as quercetin, catechins and gallic acid have b...

    Authors: Rajavel Varatharajan, Munavvar Zubaid Abdul Sattar, Ivy Chung, Mahmood Ameen Abdulla, Normadiah M Kassim and Nor Azizan Abdullah
    Citation: BMC Complementary and Alternative Medicine 2013 13:242
  14. Obesity is associated with knee pain and is an independent predictor of incident knee osteoarthritis (OA); increased pain with movement often leads patients to adopt sedentary lifestyles to avoid pain. Detaile...

    Authors: Kate L Lapane, Shibing Yang, Rachel Jawahar, Timothy McAlindon and Charles B Eaton
    Citation: BMC Complementary and Alternative Medicine 2013 13:241
  15. Ligament injuries are common clinical problems for which there are few established interventions. Instrument-assisted cross fiber massage (IACFM) was recently shown to accelerate the restoration of biomechanic...

    Authors: M Terry Loghmani and Stuart J Warden
    Citation: BMC Complementary and Alternative Medicine 2013 13:240
  16. Seropharmacology arising recently is a novel method of in vitro pharmacological study on Chinese herb using drug-containing animal serum. As seropharmacology possesses the advantages of experiments in vitro and i...

    Authors: Haibo Xu, Qinghe Wu, Cheng Peng and Lijuan Zhou
    Citation: BMC Complementary and Alternative Medicine 2013 13:239
  17. Alpinia oxyphylla is a common remedy in traditional Chinese medicine.Yakuchinone A is a major constituent of A. oxyphylla andexhibits anti-inflammatory, antitumor, antibacterial, and gastric protectiveactivities...

    Authors: Rong-Jyh Lin, Chuan-Min Yen, Tzung-Han Chou, Feng-Yu Chiang, Guey-Horng Wang, Ya-Ping Tseng, Lin Wang, Ting-Wei Huang, Hui-Chuan Wang, Leong-Perng Chan, Hsiou-Yu Ding and Chia-Hua Liang
    Citation: BMC Complementary and Alternative Medicine 2013 13:237
  18. Ischemic hypoxic brain injury often causes irreversible brain damage. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in tradi...

    Authors: Yuan-Xiao Yang, Yi-Tao Chen, Xiao-Jie Zhou, Chun-Lan Hong, Chang-Yu Li and Jian-You Guo
    Citation: BMC Complementary and Alternative Medicine 2013 13:236
  19. Guava pomace is an example of the processing waste generated after the manufacturing process from the juice industry that could be a source of bioactives. Thus, the present investigation was carried out in ord...

    Authors: Carina Denny, Priscilla S Melo, Marcelo Franchin, Adna P Massarioli, Keityane B Bergamaschi, Severino M de Alencar and Pedro L Rosalen
    Citation: BMC Complementary and Alternative Medicine 2013 13:235
  20. Nasopharyngeal carcinoma (NPC) is known for its high incidence of neck lymph node metastasis, which represents poor prognosis. The present study aimed to examine the anti-metastatic properties of Selaginella tama...

    Authors: Chung-Han Hsin, Buor-Chang Wu, Chun-Yi Chuang, Shun-Fa Yang, Yi-Hsien Hsieh, Hsin-Yu Ho, Huang-Pin Lin, Mu-Kuan Chen and Chiao-Wen Lin
    Citation: BMC Complementary and Alternative Medicine 2013 13:234
  21. Samsoeum (SSE), a traditional herbal formula, has been widely used to treat cough, fever, congestion, and emesis for centuries. Recent studies have demonstrated that SSE retains potent pharmacological efficien...

    Authors: Aeyung Kim, Nam-Hui Yim and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:233
  22. The rhizome of Hydnophytum formicarum Jack., a medicinal plant known in Thai as Hua-Roi-Roo, has been used in Thai traditional herbal medicine for treatment of cancer. We assessed the ability of its ethanolic and...

    Authors: Thanaset Senawong, Suwatchai Misuna, Somprasong Khaopha, Suporn Nuchadomrong, Prasan Sawatsitang, Chanokbhorn Phaosiri, Arpa Surapaitoon and Banchob Sripa
    Citation: BMC Complementary and Alternative Medicine 2013 13:232
  23. Vascular endothelial growth factor (VEGF) is a key regulator of physiologic and pathogenic angiogenesis in diseases such as cancer and diabetic retinopathy. It is known that cysteine proteases from plants, lik...

    Authors: Thomas Mohr and Lucia Desser
    Citation: BMC Complementary and Alternative Medicine 2013 13:231
  24. Complementary medicines, including homeopathy, are used by many patients with cancer, usually alongside with conventional treatment. However, the molecular mechanisms underneath the anti-cancer effect, if any,...

    Authors: Shilpi Saha, Dewan Md Sakib Hossain, Shravanti Mukherjee, Suchismita Mohanty, Minakshi Mazumdar, Sanhita Mukherjee, Uttam K Ghosh, Chaturbhuj Nayek, Chinta Raveendar, Anil Khurana, Rathin Chakrabarty, Gaurisankar Sa and Tanya Das
    Citation: BMC Complementary and Alternative Medicine 2013 13:230
  25. Fatty acid synthase (FAS) is a promising antifungal target due to its marked structural differences between fungal and mammalian cells. The aim of this study was to evaluate the antifungal activity of flavonoi...

    Authors: Tamires Aparecida Bitencourt, Tatiana Takahasi Komoto, Bruna Gabriele Massaroto, Carlos Eduardo Saraiva Miranda, Rene Oliveira Beleboni, Mozart Marins and Ana Lúcia Fachin
    Citation: BMC Complementary and Alternative Medicine 2013 13:229
  26. Reactive oxygen species play important roles in renal calcium crystallization. In this study, we examined the effects of catechin, which have been shown to have antioxidant properties on the renal calcium crys...

    Authors: Wei Zhai, Junhua Zheng, Xudong Yao, Bo Peng, Min Liu, Jianhua Huang, Guangchun Wang and Yunfei Xu
    Citation: BMC Complementary and Alternative Medicine 2013 13:228
  27. In Traditional Chinese Medicine (TCM), tongue diagnosis has been an important diagnostic method for the last 3000 years. Tongue diagnosis is a non-invasive, simple and valuable diagnostic tool. TCM treats the ...

    Authors: Zhu-Mei Sun, Jie Zhao, Peng Qian, Yi-Qin Wang, Wei-Fei Zhang, Chun-Rong Guo, Xiao-Yan Pang, Shun-Chun Wang, Fu-Feng Li and Qi Li
    Citation: BMC Complementary and Alternative Medicine 2013 13:227
  28. The incidence of lung cancer is expected to increase due to increases in exposure to airborne pollutants and cigarette smoke. Moringa oleifera (MO), a medicinal plant found mainly in Asia and South Africa is used...

    Authors: Charlette Tiloke, Alisa Phulukdaree and Anil A Chuturgoon
    Citation: BMC Complementary and Alternative Medicine 2013 13:226
  29. While older adults may seek care for low back pain (LBP) from both medical doctors (MDs) and doctors of chiropractic (DCs), co-management between these providers is uncommon. The purposes of this study were to...

    Authors: Kevin J Lyons, Stacie A Salsbury, Maria A Hondras, Mark E Jones, Andrew A Andresen and Christine M Goertz
    Citation: BMC Complementary and Alternative Medicine 2013 13:225
  30. Complementary medicines (CMs) are widely used by women. Although, women in Australia are frequent users of CM, few studies have examined their utilisation by women attending a family planning service. The aim ...

    Authors: Caroline A Smith, Deborah J Bateson and Edith Weisberg
    Citation: BMC Complementary and Alternative Medicine 2013 13:224
  31. The use of edible plants is an integral part of dietary behavior in the West region of Cameroon. Dorstenia psilurus (Moraceae) is widely used as spice and as medicinal plant for the treatment of several diseases ...

    Authors: Constant Anatole Pieme, Santosh Kumar Guru, Pantaleon Ambassa, Suresh Kumar, Bathelemy Ngameni, Jeanne Yonkeu Ngogang, Shashi Bhushan and Ajit Kumar Saxena
    Citation: BMC Complementary and Alternative Medicine 2013 13:223
  32. Melastoma malabathricum (MM) Linn leaves traditionally use in the treatment of diabetic conditions. The aim of the present investigation was to evaluate the antioxidant, antihyperlipidemic and antidiabetic activ...

    Authors: Vikas Kumar, Danish Ahmed, Pushpraj S Gupta, Firoz Anwar and Mohd Mujeeb
    Citation: BMC Complementary and Alternative Medicine 2013 13:222
  33. Over-proliferation of airway smooth muscle cell (ASMC) is one of the important contributors to airway remodeling in asthma. The aim of this study was to investigate the effect of Shenmai injection (SMI) on the...

    Authors: Limin Zhao, Jizhen Wu, Xiaoyu Zhang, Hongyan Kuang, Yali Guo and Lijun Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:221
  34. This study investigates the effect of Xiao-Qing-Long-Tang (XQLT) on neurotrophin in an established mouse model of Dermatophagoides pteronyssinus (Der p)-induced acute allergic asthma and in a LA4 cell line mod...

    Authors: Ren-Shiu Chang, Shulhn-Der Wang, Yu-Chin Wang, Li-Jen Lin, Shung-Te Kao and Jiu-Yao Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:220
  35. In this study, we evaluated the anti-inflammatory effect of PM014 on cigarette smoke induced lung disease in the murine animal model of chronic obstructive pulmonary disease (COPD).

    Authors: Kyung-Hwa Jung, Kyoung-Keun Haam, Soojin Park, Youngeun Kim, Seung Ryel Lee, Geunhyeog Lee, Miran Kim, Moochang Hong, Minkyu Shin, Sungki Jung and Hyunsu Bae
    Citation: BMC Complementary and Alternative Medicine 2013 13:219
  36. Berberis vulgaris is a well known plant with traditional herbal medical history. The aims of this study was to bioscreen and compare the in vitro biological activity (antioxidant, cholinergic, antidaibetic and t...

    Authors: Abeer E Abd El-Wahab, Doaa A Ghareeb, Eman EM Sarhan, Marwa M Abu-Serie and Maha A El Demellawy
    Citation: BMC Complementary and Alternative Medicine 2013 13:218
  37. Labisia Pumila var. alata (LPva) has shown potential as an alternative to estrogen replacement therapy (ERT) in prevention of estrogen-deficient osteoporosis. In earlier studies using postmenopausal model, LPva ...

    Authors: Siti Noor Fathilah, Norazlina Mohamed, Norliza Muhammad, Isa Naina Mohamed, Ima Nirwana Soelaiman and Ahmad Nazrun Shuid
    Citation: BMC Complementary and Alternative Medicine 2013 13:217
  38. Crotalaria pallida Ailton is a plant belonging to the Fabaceae family, popularly known as “rattle or rattlesnake” and used in traditional medicine to treat swelling of the joints and as a vermifuge. Previous pha...

    Authors: Paula Karina Boldrin, Flávia Aparecida Resende, Ana Paula Oliveira Höhne, Mariana Santoro de Camargo, Lívia Greghi Espanha, Catarine Haidê Nogueira, Maria do Socorro F Melo, Wagner Vilegas and Eliana Aparecida Varanda
    Citation: BMC Complementary and Alternative Medicine 2013 13:216
  39. We report results of a pilot study designed to test a novel smoking cessation intervention, Mindfulness Training for Smokers (MTS), in smokers age 18-29 years with regular episodes of binge drinking. Mindfulne...

    Authors: James M Davis, David M Mills, Kristin A Stankevitz, Alison R Manley, Matthew R Majeskie and Stevens S Smith
    Citation: BMC Complementary and Alternative Medicine 2013 13:215
  40. Ssanghwa-tang (SHT) is a widely used medication for the treatment of fatigue, pain, inflammation, hypothermia, erectile dysfunction, cancer, and osteoporosis in Asia, however, role of SHT on the melanin synthe...

    Authors: Aeyung Kim, Nam-Hui Yim, Minju Im, Young Pil Jung, Chun Liang, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:214
  41. Hyaluronidases have been found as the target enzymes in the development of osteoarthritis (OA) disease. While there is still no curative treatment for this disease, recent studies on the treatment of OA were f...

    Authors: Kamini Citalingam, Seema Zareen, Khozirah Shaari and Syahida Ahmad
    Citation: BMC Complementary and Alternative Medicine 2013 13:213
  42. Fewer than 6% patients with adenocarcinoma of the pancreas live up to five years after diagnosis. Chemotherapy is currently the standard treatment, however, these tumors often develop drug resistance over time...

    Authors: Liron Berkovich, Gideon Earon, Ilan Ron, Adam Rimmon, Akiva Vexler and Shahar Lev-Ari
    Citation: BMC Complementary and Alternative Medicine 2013 13:212
  43. Picralima nitida Stapf (Apocynaceae) is a medicinal plant used traditionally in Cameroon to cure various ailments such as gastrointestinal disorders and dysentery. This study reports the in vitro and in vivo ant...

    Authors: Laure Brigitte Mabeku Kouitcheu, Joseph Lebel Tamesse and Jacques Kouam
    Citation: BMC Complementary and Alternative Medicine 2013 13:211
  44. Human diploid fibroblasts (HDFs) undergo a limited number of cellular divisions in culture and progressively reach a state of irreversible growth arrest, a process termed cellular ageing. Even though beneficia...

    Authors: Suzana Makpol, Thong Wei Yeoh, Farah Adilah Che Ruslam, Khaizurin Tajul Arifin and Yasmin Anum Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2013 13:210
  45. Large-scale pharmaco-epidemiological studies of Chinese herbal medicine (CHM) for treatment of urticaria are few, even though clinical trials showed some CHM are effective. The purpose of this study was to exp...

    Authors: Pei-Shan Chien, Yu-Fang Tseng, Yao-Chin Hsu, Yu-Kai Lai and Shih-Feng Weng
    Citation: BMC Complementary and Alternative Medicine 2013 13:209
  46. With the emergence of strains resistant to conventional antibiotics, it is important to carry studies using alternative methods to control these microorganisms causing important infections, such as the use of ...

    Authors: Jonatas Rafael de Oliveira, Vinicius Carlos de Castro, Polyana das Graças Figueiredo Vilela, Samira Esteves Afonso Camargo, Cláudio Antonio Talge Carvalho, Antonio Olavo Cardoso Jorge and Luciane Dias de Oliveira
    Citation: BMC Complementary and Alternative Medicine 2013 13:208
  47. The naphthoquinone pigment, shikonin, is a major component of Lithospermum erythrorhizon and has been shown to have various biological functions, including antimicrobial, anti-inflammatory, and antitumor effects....

    Authors: So Young Gwon, Ji Yun Ahn, Chang Hwa Jung, Bo Kyung Moon and Tae Youl Ha
    Citation: BMC Complementary and Alternative Medicine 2013 13:207
  48. Qingfei Xiaoyan Wan (QFXY), a traditional Chinese formula, is widely used for relieving cough, asthma, upper respiratory tract infection, bronchitis, pneumonia, and etc. in clinic. Comparing with other anti-as...

    Authors: Zhenying Zhao, Yingbo Miao, Pengwei Pan, Binfeng Cheng, Gang Bai and Hong Wu
    Citation: BMC Complementary and Alternative Medicine 2013 13:206
  49. Breast cancer survivors who participate in physical activity (PA) are reported to experience improved health-related quality of life (HRQOL). However, the quantitative research exploring the relationship betwe...

    Authors: Heather A Ray and Marja J Verhoef
    Citation: BMC Complementary and Alternative Medicine 2013 13:205