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  1. The aim of this study was to determine the presence and the intensity of humoral immunity to melanoma-associated antigens: tyrosinase and melanin, in patients with melanoma, in persons with vitiligo and in con...

    Authors: Marija Đorđić, Ivana Z Matić, Ivana Filipović-Lješković, Radan Džodić, Miomir Šašić, Aleksandra Erić-Nikolić, Ana Vuletić, Branka Kolundžija, Ana Damjanović, Nađa Grozdanić, Srđan Nikolić, Janko Pralica, Danijela Dobrosavljević, Sanvila Rašković, Slađana Andrejević and Zorica Juranić
    Citation: BMC Complementary and Alternative Medicine 2012 12:109
  2. Mineral water from deep-sea bedrock, formed over thousands of years, is rich in minerals such as Ca, Mg, Na, K, Fe and others. Our present study was to investigate the preventive effects of natural deep-sea wa...

    Authors: Jong-Phil Bak, Yong-Min Kim, Jeonghyun Son, Chang-Ju Kim and Ee-Hwa Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:108
  3. Ribosome-inactivating proteins (RIP) have been studied in the search for toxins that could be used as immunotoxins for cancer treatment. Pulchellin, a type 2 RIP, is suggested to induce immune responses that h...

    Authors: Djamile Cordeiro de Matos, Lívia Carolina Abreu de Ribeiro, Aline Tansini, Lucas Souza Ferreira, Marisa Campos Polesi Placeres, Lucas Luis Colombo and Iracilda Zeppone Carlos
    Citation: BMC Complementary and Alternative Medicine 2012 12:107
  4. The skin is chronically exposed to endogenous and environmental pro-oxidant agents, leading to the harmful generation of reactive oxygen species. Antioxidant is vital substances which possess the ability to pr...

    Authors: Jamnian Chompoo, Atul Upadhyay, Masakazu Fukuta and Shinkichi Tawata
    Citation: BMC Complementary and Alternative Medicine 2012 12:106
  5. Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of p...

    Authors: Robert M Littleton, Matthew Miller and Jay R Hove
    Citation: BMC Complementary and Alternative Medicine 2012 12:105
  6. Xanthones are a group of oxygen-containing heterocyclic compounds with remarkable pharmacological effects such as anti-cancer, antioxidant, anti-inflammatory, and antimicrobial activities.

    Authors: Abdalrahim F A Aisha, Khalid M Abu-Salah, Zhari Ismail and Amin Malik Shah Abdul Majid
    Citation: BMC Complementary Medicine and Therapies 2012 12:104
  7. The efficacy of Centella asiatica for incision and burn wounds are not fully understood. Here, we report the wound healing activities of sequential hexane, ethyl acetate, methanol, and water extracts of Centella ...

    Authors: Juraiporn Somboonwong, Mattana Kankaisre, Boonyong Tantisira and Mayuree H Tantisira
    Citation: BMC Complementary and Alternative Medicine 2012 12:103
  8. Drugs dedicated to alleviate neurodegenerative diseases like Parkinson’s and Alzheimer’s have always been associated with debilitating side effects. Medicinal mushrooms which harness neuropharmacological compo...

    Authors: Chia-Wei Phan, Wei-Lun Wong, Pamela David, Murali Naidu and Vikineswary Sabaratnam
    Citation: BMC Complementary and Alternative Medicine 2012 12:102
  9. Extracts of Sasa senanensis Rehder are used in traditional Japanese medicine; however, little is known about the underlying mechanisms of their potential health benefits.

    Authors: Yuzo Nakagawa-Yagi, Yukiko Sato, Emi Matsumoto, Shin-ichi Nakatsuka, Tsuyoshi Sakaki, Yukiko Muramatsu, Takaaki Hara and Toshiro Aigaki
    Citation: BMC Complementary and Alternative Medicine 2012 12:101
  10. Drugs of plant origin such as Arnica montana, Calendula officinalis or Hypericum perforatum have been frequently used to promote wound healing. While their effect on wound healing using preparations at pharmacolo...

    Authors: Katarina Hostanska, Matthias Rostock, Joerg Melzer, Stephan Baumgartner and Reinhard Saller
    Citation: BMC Complementary and Alternative Medicine 2012 12:100
  11. Albizia adianthifolia is used traditionally in Cameroon to treat several ailments, including infectious and associated diseases. This work was therefore designed to investigate the antioxidant and antimicrobial ...

    Authors: Jean de Dieu Tamokou, Deke James Simo Mpetga, Paul Keilah Lunga, Mathieu Tene, Pierre Tane and Jules Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2012 12:99
  12. The use of complementary and alternative medicine (CAM) has increased significantly in Australia over the past decade. Back pain represents a common context for CAM use, with increasing utilisation of a wide r...

    Authors: Alex F Broom, Emma R Kirby, David W Sibbritt, Jon Adams and Kathryn M Refshauge
    Citation: BMC Complementary and Alternative Medicine 2012 12:98
  13. Complementary and alternative medicine (CAM) has frequently been used to treat tinnitus, and acupuncture is a particularly popular option. The objective of this review was to assess the evidence concerning the...

    Authors: Jong-In Kim, Jun-Yong Choi, Dong-Hyo Lee, Tae-Young Choi, Myeong Soo Lee and Edzard Ernst
    Citation: BMC Complementary and Alternative Medicine 2012 12:97
  14. Chemoprevention crossover trials of tea can be more efficient than parallel designs but the attrition and compliance rates with such trials are unknown.

    Authors: Chiranjeev Dash, Fung-Lung Chung, Joy Ann Phillips Rohan, Emily Greenspan, Patrick D Christopher, Kepher Makambi, Yukihiko Hara, Kenneth Newkirk, Bruce Davidson and Lucile L Adams-Campbell
    Citation: BMC Complementary and Alternative Medicine 2012 12:96
  15. During recent years the market for homeopathic education media has increasingly diversified with old (books, seminars) and new media (video-seminars, pc-programs, homeo-wiki and internet-courses). However, lit...

    Authors: Max Escher, Horst Christian Vollmar, Andreas Holling, Christa Raak and Thomas Ostermann
    Citation: BMC Complementary and Alternative Medicine 2012 12:95
  16. Astragalus polysaccharides (APS) are active constituents of Astragalus membranaceus. They have been widely studied, especially with respect to their immunopotentiating properties, their ability to counteract the ...

    Authors: Qing E Tian, Huan De Li, Miao Yan, Hua-Lin Cai, Qin-You Tan and Wen-Yuan Zhang
    Citation: BMC Complementary and Alternative Medicine 2012 12:94
  17. Numerous studies have demonstrated that autophagy plays a vital role in maintaining cellular homeostasis. Interestingly, several anticancer agents were found to exert their anticancer effects by triggering aut...

    Authors: Chuan Bian Lim, Pan You Fu, Nung Ky, Hong Shuang Zhu, XiaoLing Feng, Jinming Li, Kandhadayar Gopalan Srinivasan, Mohamed Sabry Hamza and Yan Zhao
    Citation: BMC Complementary and Alternative Medicine 2012 12:93
  18. Zingiber officinale R. rhizome (ginger) is a popular spice that has traditionally been used to combat the effects of various inflammatory diseases. The aim of this study was to evaluate the effects of ginger on p...

    Authors: Parvin Rahnama, Ali Montazeri, Hassan Fallah Huseini, Saeed Kianbakht and Mohsen Naseri
    Citation: BMC Complementary and Alternative Medicine 2012 12:92
  19. Toxoplasma gondii infection causes toxoplasmosis, an infectious disease with worldwide prevalence. The limited efficiency of drugs against this infection, their side effects and the potential appearance of resis...

    Authors: Nowroji Kavitha, Rahmah Noordin, Kit-Lam Chan and Sreenivasan Sasidharan
    Citation: BMC Complementary and Alternative Medicine 2012 12:91
  20. Sonchus asper (SAME) is used as a folk medicine in hepatic disorders. In this study, the hepatoprotective effects of the methanol extract of SAME was evaluated against carbon tetrachloride (CCl4)-induced liver i...

    Authors: Rahmat A Khan, Muhammad R Khan, Sumaira Sahreen and Naseer Ali Shah
    Citation: BMC Complementary and Alternative Medicine 2012 12:90
  21. Sesquiterpene lactones (SL) are plant secondary metabolites that are known for their anti-fungal, anti-bacterial, anti-inflammatory, and anti-tumor properties. Considering that several SL-derived drugs are cur...

    Authors: Melody Saikali, Akram Ghantous, Racha Halawi, Salma N Talhouk, Najat A Saliba and Nadine Darwiche
    Citation: BMC Complementary and Alternative Medicine 2012 12:89
  22. Assisted reproductive technologies (ART) are increasingly utilised for resolving difficulties conceiving. These technologies are expensive to both the public purse and the individual consumers. Acupuncture is ...

    Authors: Caroline A Smith, Suzanne Grant, Jane Lyttleton and Suzanne Cochrane
    Citation: BMC Complementary and Alternative Medicine 2012 12:88
  23. Medicinal plants are possible sources for future novel antioxidant compounds in food and pharmaceutical formulations. Recent attention on medicinal plants emanates from their long historical utilisation in fol...

    Authors: Stephen O Amoo, Adeyemi O Aremu, Mack Moyo and Johannes Van Staden
    Citation: BMC Complementary and Alternative Medicine 2012 12:87
  24. The extent to which racial differences exist in use of treatments for osteoarthritis (OA) is debatable. The purpose of this study was to describe the differences between African Americans (AA) and Caucasian Am...

    Authors: Shibing Yang, Rachel Jawahar, Timothy E McAlindon, Charles B Eaton and Kate L Lapane
    Citation: BMC Complementary and Alternative Medicine 2012 12:86
  25. Sasang constitutional medicine (SCM) is a unique form of traditional Korean medicine that divides human beings into four constitutional types (Tae-Yang: TY, Tae-Eum: TE, So-Yang: SY, and So-Eum: SE), which dif...

    Authors: Jun-Hyeong Do, Eunsu Jang, Boncho Ku, Jun-Su Jang, Honggie Kim and Jong Yeol Kim
    Citation: BMC Complementary and Alternative Medicine 2012 12:85
  26. Infection with HIV-1 results in marked immunologic insults and structural damage to the intestinal mucosa, including compromised barrier function. While the development of highly active antiretroviral therapy ...

    Authors: Marco Schunter, Hiutung Chu, Timothy L Hayes, Delandy McConnell, Sean S Crawford, Paul A Luciw, Stig Bengmark, David M Asmuth, Jennifer Brown, Charles L Bevins, Barbara L Shacklett and J William Critchfield
    Citation: BMC Complementary and Alternative Medicine 2012 12:84
  27. Dorstenia mannii (Moraceae) is a medicinal herb used traditionally for the treatment of many diseases. In the present study, the methanol extract of D. mannii and nine of its isolated compounds, namely dorsmanin...

    Authors: Armelle T Mbaveng, Victor Kuete, Bathelemy Ngameni, Veronique P Beng, Bonaventure T Ngadjui, Jacobus J Marion Meyer and Namrita Lall
    Citation: BMC Complementary and Alternative Medicine 2012 12:83
  28. Parkinson’s disease is a high incidence neurodegenerative disease in elderly people, and oxidative stress plays an important role in the pathogenesis. Oxygen metabolism in the brain is high, which lacks an ant...

    Authors: Qinyong Ye, Linfeng Ye, Xianjie Xu, Bixia Huang, Xiaodong Zhang, Yuangui Zhu and Xiaochun Chen
    Citation: BMC Complementary and Alternative Medicine 2012 12:82
  29. In 1957, Tunisia introduced 117 species of Eucalyptus; they have been used as fire wood, for the production of mine wood and to fight erosion. Actually, Eucalyptus essential oil is traditionally used to treat res...

    Authors: Ameur Elaissi, Zyed Rouis, Nabil Abid Ben Salem, Samia Mabrouk, Youssef ben Salem, Karima Bel Haj Salah, Mahjoub Aouni, Farhat Farhat, Rachid Chemli, Fethia Harzallah-Skhiri and Mohamed Larbi Khouja
    Citation: BMC Complementary and Alternative Medicine 2012 12:81
  30. Periodontal diseases are bacterial infections leading to chronic inflammation disorders that are frequently observed in adults. In the present study, we evaluated the effect of auraptene and lacinartin, two na...

    Authors: Annie Marquis, Salvatore Genovese, Francesco Epifano and Daniel Grenier
    Citation: BMC Complementary and Alternative Medicine 2012 12:80
  31. The herbal preparation DAS-77, used for the treatment of various ailments in Nigeria, contains the milled bark of Mangifera indica L. and root of Carica papaya L. Toxicological assessment of the preparation was c...

    Authors: Saheed O Afolabi, Abidemi J Akindele, Olufunsho Awodele, Chidozie C Anunobi and Olufunmilayo O Adeyemi
    Citation: BMC Complementary and Alternative Medicine 2012 12:79
  32. Crassocephalum crepidioides, a plant distributed in Okinawa Islands, is known in folk medicine; however, its anticancer activity has not been investigated. The aim of this study was to determine the in vitro and...

    Authors: Koh Tomimori, Shinji Nakama, Ryuichiro Kimura, Kazumi Tamaki, Chie Ishikawa and Naoki Mori
    Citation: BMC Complementary and Alternative Medicine 2012 12:78
  33. Traditional Indian and Australian medicinal plant extracts were investigated to determine their therapeutic potential to inhibit key enzymes in carbohydrate metabolism, which has relevance to the management of...

    Authors: Vandana Gulati, Ian H Harding and Enzo A Palombo
    Citation: BMC Complementary and Alternative Medicine 2012 12:77
  34. Essential oil of Pimpinella anisum L. Apiaceae (anise oil) has been widely used in traditional Persian medicine to treat a variety of diseases, including some neurological disorders. This study was aimed to test ...

    Authors: Fariba Karimzadeh, Mahmoud Hosseini, Diana Mangeng, Hassan Alavi, Gholam Reza Hassanzadeh, Mohamad Bayat, Maryam Jafarian, Hadi Kazemi and Ali Gorji
    Citation: BMC Complementary and Alternative Medicine 2012 12:76
  35. To evaluate different types of acupuncture treatment for migraine in China from the perspective of health economics, particularly the comparison between treatment of specific acupoints in Shaoyang meridians an...

    Authors: Zhu-qing Deng, Hui Zheng, Ling Zhao, Si-yuan Zhou, Ying Li and Fan-rong Liang
    Citation: BMC Complementary and Alternative Medicine 2012 12:75
  36. Nearly 3,000 plant species are used as medicines in South Africa, with approximately 350 species forming the most commonly traded and used medicinal plants. In the present study, twelve South African medicinal...

    Authors: Trine R H Nielsen, Victor Kuete, Anna K Jäger, Jacobus J Marion Meyer and Namrita Lall
    Citation: BMC Complementary and Alternative Medicine 2012 12:74