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  1. Oxidative stress has been implicated in the progression of various diseases, which may result in the depletion of endogenous antioxidants. Exogenous supplementation with antioxidants could result in increased ...

    Authors: Werner Cordier, Mary Gulumian, Allan Duncan Cromarty and Vanessa Steenkamp
    Citation: BMC Complementary and Alternative Medicine 2013 13:116
  2. Chromatin, residing in the nuclei of eukaryotic cells, comprises DNA and histones to make up chromosomes. Chromatin condenses to compact the chromosomes and loosens to facilitate gene transcription and DNA rep...

    Authors: Hsin-Ying Hsieh, Pei-Hsun Chiu and Sun-Chong Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:115
  3. Reflexology is an alternative medical practice that produces beneficial effects by applying pressure to specific reflex areas. Our previous study suggested that reflexological stimulation induced cortical acti...

    Authors: Naoki Miura, Yuko Akitsuki, Atsushi Sekiguchi and Ryuta Kawashima
    Citation: BMC Complementary and Alternative Medicine 2013 13:114
  4. Distressed individuals in Korea may benefit from the practice of mind–body exercises such as Qigong. However, the effectiveness of such techniques needs to be investigated.

    Authors: Eun-Young Hwang, Sun-Yong Chung, Jae-Heung Cho, Mi-Yeon Song, Sehyun Kim and Jong-Woo Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:113
  5. Osteoclasts are primarily responsible for bone resorption. In many pathological bone diseases including osteoporosis and rheumatoid arthritis, osteoclasts are excessively activated. Thus, controlling of osteoc...

    Authors: Hyunil Ha, Ki-Shuk Shim, Hyosun An, Taesoo Kim and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:112
  6. Plants of the genus Maytenus belong to the family Celastraceae and are widely used in folk medicine as anti-tumour, anti-asthmatic, analgesic, anti-inflammatory, antimicrobial and anti-ulcer agents, and as a trea...

    Authors: Tsholofelo Abednego Mokoka, Lyndy Joy McGaw, Ladislaus Kakore Mdee, Victor Patrick Bagla, Ezekiel Olugbenga Iwalewa and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:111
  7. Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.

    Authors: Adelina Jiménez-Arellanes, Julieta Luna-Herrera, Ricardo Ruiz-Nicolás, Jorge Cornejo-Garrido, Amparo Tapia and Lilián Yépez-Mulia
    Citation: BMC Complementary and Alternative Medicine 2013 13:109
  8. Traditional Japanese Medicine (Kampo) is often used in Japan, but very little data on its users are available. We investigated who uses Kampo, the reasons and opinions for its use.

    Authors: Lydia Hottenbacher, Thorolf ER Weißhuhn, Kenji Watanabe, Takashi Seki, Julia Ostermann and Claudia M Witt
    Citation: BMC Complementary and Alternative Medicine 2013 13:108
  9. Teas from the husk fiber of Cocos nucifera are used in the folk medicine to treat arthritis and other inflammatory processes. Some works show that some varieties have biological activities. However, one of the ma...

    Authors: Rafaela Ribeiro Silva, Davi Oliveira e Silva, Humberto Rollemberg Fontes, Celuta Sales Alviano, Patricia Dias Fernandes and Daniela Sales Alviano
    Citation: BMC Complementary and Alternative Medicine 2013 13:107
  10. Hwangryun-haedok-tang (HRT) is traditional herbal medicine used to treat inflammatory-related diseases in Asia. However, its effect on osteoclastogenesis and bone loss is still unknown. In this study, we evalu...

    Authors: Ki-Shuk Shim, Taesoo Kim, Hyunil Ha, Kwang Jin Lee, Chang-Won Cho, Han Sung Kim, Dong-Hyun Seo and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:106
  11. Radiation-induced skin injury is a common complication of radiotherapy. The RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract (RCE) can ameliorate radiation-induced skin injury in our clinical observation. Bu...

    Authors: Xi-Jing Wang, Shuai Lin, Hua-Feng Kang, Zhi-Jun Dai, Ming-Hua Bai, Xiu-Long Ma, Xiao-Bin Ma, Meng-jie Liu, Xiao-Xu Liu and Bao-Feng Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:105
  12. Diabetes remains a major health problem worldwide. Low-risk low-cost alternatives to pharmaceutical interventions are needed where lifestyle modifications have failed. We conducted a double-blind randomised pl...

    Authors: Suzanne J Grant, Dennis Hsu-Tung Chang, Jianxun Liu, Vincent Wong, Hosen Kiat and Alan Bensoussan
    Citation: BMC Complementary and Alternative Medicine 2013 13:104
  13. Radiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage. We examined the protective effect of genistein in tumor-bearing mice after a...

    Authors: Tae Gen Son, Eun Ji Gong, Min Ji Bae, Sung Dae Kim, Kyu Heo, Changjong Moon, Kwangmo Yang and Joong Sun Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:103
  14. Like any other form of healthcare, acupuncture takes place in a particular context which can enhance or diminish treatment outcomes (i.e. can produce contextual effects). Patients’ expectations of acupuncture ...

    Authors: Felicity L Bishop and George T Lewith
    Citation: BMC Complementary and Alternative Medicine 2013 13:102
  15. Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic act...

    Authors: Muhammad Mutassim Billah, Rafikul Islam, Hajera Khatun, Shahnaj Parvin, Ekramul Islam, SM Anisul Islam and Akbar Ali Mia
    Citation: BMC Complementary and Alternative Medicine 2013 13:101
  16. Microbial infections and resulting inflammation and oxidative stress are common pathogenesis of gastrointestinal tract (GIT) disorders. In South Africa, several species of the genus Maytenus are used in tradition...

    Authors: Aroke Shahid Ahmed, Lyndy J McGaw and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:100
  17. The aims of this study were to evaluate the antioxidant activity and to identify the antioxidant components of a traditional Chinese medicine formula consisting of a combination of Shanzha (the fruit of Crataegus...

    Authors: Cheng-Yu Chen, Hua Li, Ya-Nan Yuan, Hui-Qing Dai and Bin Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:99
  18. Anemia is a condition that has multiple origins. One such origin is the destruction of red blood cells’ (RBCs) membrane induced by free radicals. Treatment of anemia could therefore be enhanced by the use of f...

    Authors: Prosper Cabral Nya Biapa, Horea Matei, Ştefana Bâlici, Julius Eyong Oben and Jeanne Yonkeu Ngogang
    Citation: BMC Complementary and Alternative Medicine 2013 13:98
  19. St. John’s wort (Hypericum perforatum L.) is an herbaceous plant that is native to Europe, West Asia and North Africa and that is recognized and used worldwide for the treatment of mild and moderate depression. I...

    Authors: Ana Paula Peron, Rosinete Gonçalves Mariucci, Igor Vivian de Almeida, Elisângela Düsman, Mário Sérgio Mantovani and Veronica Elisa Pimenta Vicentini
    Citation: BMC Complementary and Alternative Medicine 2013 13:97
  20. The current work is an attempt to know about additional chemical profile of Artemisia macrocephala. Antioxidant activity is performed as the plant is reported to contain flavonoids, which have antioxidant activit...

    Authors: Niaz Ali, Ismail Shah, Syed Wadood Ali Shah, Ghayour Ahmed, Mohammad Shoaib, Muhammad Junaid, Waqar Ali and Zahoor Ahmed
    Citation: BMC Complementary and Alternative Medicine 2013 13:96
  21. During the last decades, the number of people suffering from dermatophytoses has seriously increased, mainly due to the development of resistant strains of microorganisms to a range of formally efficient antib...

    Authors: Guy Sedar Singor Njateng, Donatien Gatsing, Raymond Simplice Mouokeu, Paul Keilah Lunga and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2013 13:95
  22. Some Ficus species have been used in traditional African medicine in the treatment of diabetes. The antidiabetic potential of certain species has been confirmed in vivo but the mechanism of activity remains uncer...

    Authors: Oyinlola O Olaokun, Lyndy J McGaw, Jacobus N Eloff and Vinny Naidoo
    Citation: BMC Complementary and Alternative Medicine 2013 13:94
  23. Ginkgo biloba extract (GbE) is used extensively by breast cancer patients undergoing treatment with Tamoxifen (TAM). Thus, the present study investigated the effects of GbE in female Sprague–Dawley (SD) rats bea...

    Authors: Marcos Correa Dias, Kelly Silva Furtado, Maria Aparecida Marchesan Rodrigues and Luís Fernando Barbisan
    Citation: BMC Complementary and Alternative Medicine 2013 13:93
  24. Prunus yedoensis (PY) is a traditional anti-allergy and anti-inflammatory herb medicine used in South Korea. However, until date, little is known regarding its mechanism of action.

    Authors: Juyeong Lee, Gabsik Yang, Kyungjin Lee, Mi-Hwa Lee, Ji-Whan Eom, Inhye Ham and Ho-Young Choi
    Citation: BMC Complementary and Alternative Medicine 2013 13:92
  25. Scutellaria baicalensis (S. baicalensis) is one of the traditional Chinese medicinal herbs that have been shown to possess many health benefits. In the present study, we evaluated the in vitro antiviral activity...

    Authors: Keivan Zandi, Tong-Hye Lim, Nor-Aziyah Rahim, Meng-Hooi Shu, Boon-Teong Teoh, Sing-Sin Sam, Mohammed-Bashar Danlami, Kim-Kee Tan and Sazaly Abubakar
    Citation: BMC Complementary and Alternative Medicine 2013 13:91
  26. Cranberry fruits possess many biological activities partly due to their various phenolic compounds; however the underlying modes of action are poorly understood. We studied the effect of cranberry fruit extrac...

    Authors: Moussa S Diarra, Glenn Block, Heidi Rempel, B Dave Oomah, Judy Harrison, Jason McCallum, Simon Boulanger, Éric Brouillette, Mariza Gattuso and François Malouin
    Citation: BMC Complementary and Alternative Medicine 2013 13:90
  27. Activated hepatic stellate cells (aHSCs) play an important role in the progression of hepatocellular carcinoma (HCC). Here, we determined if cytokines secreted in response to the herbal compound “Songyou Yin” ...

    Authors: Qing-An Jia, Zhi-Ming Wang, Zheng-Gang Ren, Yang Bu, Xiao-Ying Xie, Yan-Hong Wang, Lan Zhang, Qiang-Bo Zhang, Tong-Chun Xue, Li-Fen Deng and Zhao-You Tang
    Citation: BMC Complementary and Alternative Medicine 2013 13:89
  28. Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery protocols. We present CamMedNP - a new database begin...

    Authors: Fidele Ntie-Kang, James A Mbah, Luc Meva’a Mbaze, Lydia L Lifongo, Michael Scharfe, Joelle Ngo Hanna, Fidelis Cho-Ngwa, Pascal Amoa Onguéné, Luc C Owono Owono, Eugene Megnassan, Wolfgang Sippl and Simon MN Efange
    Citation: BMC Complementary and Alternative Medicine 2013 13:88
  29. Tai Chi training enhances physical function and may reduce falls in older adults with and without balance disorders, yet its effect on postural control as quantified by the magnitude or speed of center-of-pres...

    Authors: Brad Manor, Lewis A Lipsitz, Peter M Wayne, C-K Peng and Li Li
    Citation: BMC Complementary and Alternative Medicine 2013 13:87
  30. Neurotoxin-Nna (NT), an analgesic peptide separated from the venom of Naja naja atra, has reported to have an exceptional specificity to block transmission of the nerve impulse by binding to the α- subunit of ...

    Authors: Yeping Ruan, Li Yao, Bingbing Zhang, Shuijuan Zhang and Jianyou Guo
    Citation: BMC Complementary and Alternative Medicine 2013 13:86
  31. Herpes viruses are important human pathogens that can cause mild to severe lifelong infections with high morbidity. They remain latent in the host cells and can cause recurrent infections that might prove fata...

    Authors: Syed Hussain Basha, Deepthi Talluri and Nalini Prasad Raminni
    Citation: BMC Complementary and Alternative Medicine 2013 13:85
  32. Flight simulators have been used to train pilots to experience and recognize spatial disorientation, a condition in which pilots incorrectly perceive the position, location, and movement of their aircrafts. Ho...

    Authors: Hsin Chu, Min-Hui Li, Yu-Cheng Huang and Shih-Yu Lee
    Citation: BMC Complementary and Alternative Medicine 2013 13:84
  33. Research suggests that since the collapse of the Soviet Union there has been a sharp growth in the use of complementary and alternative medicine (CAM) in some former Soviet countries. However, as yet, comparat...

    Authors: Andrew Stickley, Ai Koyanagi, Erica Richardson, Bayard Roberts, Dina Balabanova and Martin McKee
    Citation: BMC Complementary and Alternative Medicine 2013 13:83
  34. Chronic work-related stress is an independent risk factor for cardiometabolic diseases and associated mortality, particularly when compounded by a sedentary work environment. The purpose of this study was to d...

    Authors: Birinder S Cheema, Angelique Houridis, Lisa Busch, Verena Raschke-Cheema, Geoff W Melville, Paul W Marshall, Dennis Chang, Bianca Machliss, Chris Lonsdale, Julia Bowman and Ben Colagiuri
    Citation: BMC Complementary and Alternative Medicine 2013 13:82
  35. Multidrug resistance is a worrying cause of treatment failure in bacterial infections. The search of bioactive constituents from medicinal plants against multidrug resistant (MDR) bacteria has significantly ev...

    Authors: Hugues Fouotsa, Armelle T Mbaveng, Celine D Mbazoa, Augustin E Nkengfack, Shaheen Farzana, Choudhary M Iqbal, Jacobus J Marion Meyer, Namrita Lall and Victor Kuete
    Citation: BMC Complementary and Alternative Medicine 2013 13:81
  36. To address knowledge gaps regarding natural health product (NHP) usage in mental health populations, we examined their use in adults with mood disorders, and explored the potential for adverse events.

    Authors: Karen M Davison and Bonnie J Kaplan
    Citation: BMC Complementary and Alternative Medicine 2013 13:80
  37. Plants that are used as traditional medicine represent a relevant pool for selecting plant candidates that may have anticancer properties. In this study, the ethnomedicinal approach was used to select several ...

    Authors: Saudat Adamson Fadeyi, Olugbeminiyi O Fadeyi, Adedeji A Adejumo, Cosmas Okoro and Elbert Lewis Myles
    Citation: BMC Complementary and Alternative Medicine 2013 13:79
  38. In Cameroon, the use of edible plants is an integral part of dietarybehavior. However, evidence of the antimicrobial as well as the cytotoxiceffects of many of them has not been investigated. In the present st...

    Authors: Jean Paul Dzoyem, Santosh Kumar Guru, Constant Anatole Pieme, Victor Kuete, Akash Sharma, Inshad Ali Khan, Ajit Kumar Saxena and Ram Anuj Vishwakarma
    Citation: BMC Complementary and Alternative Medicine 2013 13:78
  39. Populations in Africa mostly rely on herbal concoctions for their primarily health care, but so far scientific studies supporting the use of plants in traditional medicine remain poor. The present study was un...

    Authors: Akadiri Yessoufou, Joachim Gbenou, Oussama Grissa, Aziz Hichami, Anne-Marie Simonin, Zouhair Tabka, Mansourou Moudachirou, Kabirou Moutairou and Naim A Khan
    Citation: BMC Complementary and Alternative Medicine 2013 13:77
  40. Diabetic nephropathy is an emergent issue in China with increase in patients with type II diabetes. There are several successful Chinese herbal products for the treatment of patients with diabetic nephropathy ...

    Authors: Jingai Fang, Hongkun Wei, Yanyan Sun, Xiaodong Zhang, Wenyuan Liu, Qintao Chang, Ruihua Wang and Yuewen Gong
    Citation: BMC Complementary and Alternative Medicine 2013 13:76
  41. Petroselinum crispum, a bright green biennial shrub is widely used traditionally as a food additive and herbal remedies for many ailments. This study therefore aimed to assess the toxic effects of its leaf extra...

    Authors: Emmanuel Olorunju Awe and S Olatunbosun Banjoko
    Citation: BMC Complementary and Alternative Medicine 2013 13:75
  42. Several treatment alternatives are available for primary breast cancer, although those for metastatic disease or inflammation associated with tumor progression are ineffective. Therefore, there is a great need...

    Authors: Claudia Urueña, Juan Mancipe, John Hernandez, Diana Castañeda, Luis Pombo, Alejandra Gomez, Alexzander Asea and Susana Fiorentino
    Citation: BMC Complementary and Alternative Medicine 2013 13:74
  43. The use of complementary and alternative medicines (CAM) and CAM practitioners is common, most frequently for the management of musculoskeletal conditions. Knowledge is limited about the use of CAM practitione...

    Authors: Laurann Yen, Tanisha Jowsey and Ian S McRae
    Citation: BMC Complementary and Alternative Medicine 2013 13:73
  44. Infertility is a common complication in diabetic men and experimental animals, mainly due to loss of germ cells by apoptotic cell death. The aim of this study was to evaluate the effects of aqueous and ethanol...

    Authors: Modeste Wankeu-Nya, Adrian Florea, Stefana Bâlici, Pierre Watcho, Horea Matei and Albert Kamanyi
    Citation: BMC Complementary and Alternative Medicine 2013 13:71
  45. The present study was aimed to provide ethnopharmacological basis for the medicinal use of Viola betonicifolia whole plant in indigestion and constipation.

    Authors: Naveed Muhammad, Najeeb ur Rehman, Haroon Khan, Muhammad Saeed and Anwarul-Hassan Gilani
    Citation: BMC Complementary and Alternative Medicine 2013 13:70
  46. The effect of massage therapy on bone metabolism in adults has only scarcely been explored. In a randomized crossover trial, we investigated the skeletal effect of Thai traditional massage by examining the cha...

    Authors: Sunee Saetung, La-or Chailurkit and Boonsong Ongphiphadhanakul
    Citation: BMC Complementary and Alternative Medicine 2013 13:69