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  1. Records have shown that Combretum adenogonium Steud. Ex A. Rich (Combretaceae) is used in traditional medicine systems of several tribes in Tanzania. This study focused on the investigation of antibacterial activ...

    Authors: Novatus F Mushi, Zakaria H Mbwambo, Ester Innocent and Supinya Tewtrakul
    Citation: BMC Complementary and Alternative Medicine 2012 12:163
    Content type: Research article Published on:

  2. Mindfulness-based stress reduction (MBSR) is frequently used for pain conditions. While systematic reviews on MBSR for chronic pain have been conducted, there are no reviews for specific pain conditions. There...

    Authors: Holger Cramer, Heidemarie Haller, Romy Lauche and Gustav Dobos
    Citation: BMC Complementary and Alternative Medicine 2012 12:162
    Content type: Research article Published on:

  3. Chronic knee pain is a common and disabling condition in people over 50 years of age, with knee joint osteoarthritis being a major cause. Acupuncture is a popular form of complementary and alternative medicine...

    Authors: Rana S Hinman, Paul McCrory, Marie Pirotta, Ian Relf, Kay M Crossley, Prasuna Reddy, Andrew Forbes, Anthony Harris, Ben R Metcalf, Mary Kyriakides, Kitty Novy and Kim L Bennell
    Citation: BMC Complementary and Alternative Medicine 2012 12:161
    Content type: Study protocol Published on:

  4. Our ongoing research has revealed that total saponins extracted from the medicinal herb Radix Astragali (AST) exhibits significant growth-inhibitory and proapoptotic effects in human cancer cells. In the prese...

    Authors: Pui-Ching Law, Kathy K Auyeung, Lok-Yi Chan and Joshua K Ko
    Citation: BMC Complementary and Alternative Medicine 2012 12:160
    Content type: Research article Published on:

  5. Complementary and alternative medicine (CAM) is becoming a popular treatment for modulating diverse immune disorders. Phellinus linteus (P. linteus) as one of the CAMs has been used to modulate cancers, inflammat...

    Authors: Ji Sun Hwang, Ho-Keun Kwon, Jung-Eun Kim, Jeonghae Rho and Sin-Hyeog Im
    Citation: BMC Complementary and Alternative Medicine 2012 12:159
    Content type: Research article Published on:

  6. Despite the growing popularity of massage, its effectiveness for treating neck pain remains unclear, largely because of the poor quality of research. A major deficiency of previous studies has been their use o...

    Authors: Karen J Sherman, Andrea J Cook, Janet R Kahn, Rene J Hawkes, Robert D Wellman and Daniel C Cherkin
    Citation: BMC Complementary and Alternative Medicine 2012 12:158
    Content type: Study protocol Published on:

  7. Abnormal Savda Munziq (ASMq), a traditional uyghur medicine, has shown anti-tumour properties in vitro. This study attempts to confirm these effects in vivo and measure effects on the immune system.

    Authors: Ainiwaer Aikemu, Anwar Umar, Abdiryim Yusup, Halmurat Upur, Bénédicte Berké, Bernard Bégaud and Nicholas Moore
    Citation: BMC Complementary and Alternative Medicine 2012 12:157
    Content type: Research article Published on:

  8. At present there is no effective and accepted therapy for hepatic fibrosis. Transforming growth factor (TGF)-β1 signaling pathway contributes greatly to hepatic fibrosis. Reducing TGF-β synthesis or inhibiting...

    Authors: Qun-yan Yao, Bei-li Xu, Ji-yao Wang, Hong-chun Liu, Shun-cai Zhang and Chuan-tao Tu
    Citation: BMC Complementary and Alternative Medicine 2012 12:156
    Content type: Research article Published on:

  9. Evidence is lacking for multi-ingredient herbal supplements claiming therapeutic effect in sexual dysfunction in men. We examined the safety and efficacy of VigRX Plus (VXP) – a proprietary polyherbal preparat...

    Authors: Gaurang R Shah, Manojkumar V Chaudhari, Suresh B Patankar, Shrikant V Pensalwar, Vilas P Sabale and Navneet A Sonawane
    Citation: BMC Complementary and Alternative Medicine 2012 12:155
    Content type: Research article Published on:

  10. Type 2 diabetes (T2D) is a complex metabolic disorder characterized by insulin resistance and hyperglycemia. Peroxisome proliferator-activated receptor gamma (PPARγ) is a key transcription factor and plays an ...

    Authors: Yunkyung Han, Hyo Won Jung and Yong-Ki Park
    Citation: BMC Complementary and Alternative Medicine 2012 12:154
    Content type: Research article Published on:

  11. Plants play a significant role in maintaining human health and improving the quality of human life. They serve humans well as valuable components of food, as well as in cosmetics, dyes, and medicines. In fact,...

    Authors: Fadwa Chaabane, Jihed Boubaker, Amira Loussaif, Aicha Neffati, Somaya Kilani-Jaziri, Kamel Ghedira and Leila Chekir-Ghedira
    Citation: BMC Complementary and Alternative Medicine 2012 12:153
    Content type: Research article Published on:

  12. Eurycoma longifolia (EL) has been shown recently to protect against bone calcium loss in orchidectomised rats, the model for androgen-deficient osteoporosis. The mechanism behind this is unclear but it may be re...

    Authors: Ahmad Nazrun Shuid, Eman El-arabi, Nadia Mohd Effendy, Halimaton Saadiah Abdul Razak, Norliza Muhammad, Norazlina Mohamed and Ima Nirwana Soelaiman
    Citation: BMC Complementary and Alternative Medicine 2012 12:152
    Content type: Research article Published on:

  13. The leaves of Caylusea abyssinica (fresen.) Fisch. & Mey. (Resedaceae), a plant widely distributed in East African countries, have been used for management of diabetes mellitus in Ethiopian folklore medicine. How...

    Authors: Wondmagegn Tamiru, Ephrem Engidawork and Kaleab Asres
    Citation: BMC Complementary and Alternative Medicine 2012 12:151
    Content type: Research article Published on:

  14. Homeopathy is widely used, and many European physicians practice homeopathy in addition to conventional medicine. Adverse effects in homeopathy are not expected by homeopaths due to the negligible quantities o...

    Authors: Trine Stub, Terje Alræk and Anita Salamonsen
    Citation: BMC Complementary and Alternative Medicine 2012 12:150
    Content type: Research article Published on:

  15. Kalanchoe tubiflora (KT) is a succulent plant native to Madagascar, and is commonly used as a medicinal agent in Southern Brazil. The underlying mechanisms of tumor suppression are largely unexplored.

    Authors: Yi-Jen Hsieh, Ming-Yeh Yang, Yann-Lii Leu, Chinpiao Chen, Chin-Fung Wan, Meng-Ya Chang and Chih-Jui Chang
    Citation: BMC Complementary and Alternative Medicine 2012 12:149
    Content type: Research article Published on:

  16. There is a need for more Comparative Effectiveness Research (CER) to strengthen the evidence base for clinical and policy decision-making. Effectiveness Guidance Documents (EGD) are targeted to clinical resear...

    Authors: Claudia M Witt, Mikel Aickin, Trini Baca, Dan Cherkin, Mary N Haan, Richard Hammerschlag, Jason Jishun Hao, George A Kaplan, Lixing Lao, Terri McKay, Beverly Pierce, David Riley, Cheryl Ritenbaugh, Kevin Thorpe, Sean Tunis, Jed Weissberg…
    Citation: BMC Complementary and Alternative Medicine 2012 12:148
    Content type: Correspondence Published on:

  17. Common cold is caused by a variety of respiratory viruses. The prevalence in children is high, and it potentially contributes to significant morbidity. Iota-carragenan, a polymer derived from red seaweed, has ...

    Authors: Tamas Fazekas, Philipp Eickhoff, Nathalie Pruckner, Georg Vollnhofer, Gustav Fischmeister, Christopher Diakos, Margit Rauch, Maria Verdianz, Andreas Zoubek, Helmut Gadner and Thomas Lion
    Citation: BMC Complementary and Alternative Medicine 2012 12:147
    Content type: Research article Published on:

  18. Traditional Chinese Medicine (TCM) is one of the most popular complementary and alternative medicine modalities worldwide. In Chinese and East Asian societies, TCM plays an active role in the modern health car...

    Authors: Yueh-Hsiang Liao, Cheng-Chieh Lin, Tsai-Chung Li and Jaung-Geng Lin
    Citation: BMC Complementary and Alternative Medicine 2012 12:146
    Content type: Research article Published on:

  19. Obesity is recognized as a social problem, associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to...

    Authors: Neerja Rani, Neeru Vasudeva and Surendra Kumar Sharma
    Citation: BMC Complementary and Alternative Medicine 2012 12:145
    Content type: Research article Published on:

  20. The 70% methanol extract of Terminalia chebula Retz. fruit (TCME) was investigated for its in vitro iron chelating property and in vivo ameliorating effect on hepatic injury of iron overloaded mice.

    Authors: Rhitajit Sarkar, Bibhabasu Hazra and Nripendranath Mandal
    Citation: BMC Complementary and Alternative Medicine 2012 12:144
    Content type: Research article Published on:

  21. The molecular mechanisms of dietary oils (such as fish oil) and unsaturated fatty acids, which are widely used by the public for anti-inflammation and vascular protection, have not been settled yet. In this st...

    Authors: Diana Ruan and Shui-Ping So
    Citation: BMC Complementary and Alternative Medicine 2012 12:143
    Content type: Research article Published on:

  22. Methanolic extracts of Gracilaria tenuistipitata (MEGT) were obtained from the edible red algae. Previously, we found that water extract of G. tenuistipitata was able to modulate oxidative stress-induced DNA dama...

    Authors: Chi-Chen Yeh, Jing-Iong Yang, Jin-Ching Lee, Chao-Neng Tseng, Ya-Ching Chan, You-Cheng Hseu, Jen-Yang Tang, Li-Yeh Chuang, Hurng-Wern Huang, Fang-Rong Chang and Hsueh-Wei Chang
    Citation: BMC Complementary and Alternative Medicine 2012 12:142
    Content type: Research article Published on:

  23. The improvement of axonal regeneration is a major objective in the treatment of peripheral nerve injuries. The aim of this study was to evaluate the effects of electro-acupuncture on the functional recovery of...

    Authors: Ngoc Son Hoang, Chamroeun Sar, Jean Valmier, Victor Sieso and Frédérique Scamps
    Citation: BMC Complementary and Alternative Medicine 2012 12:141
    Content type: Research article Published on:

  24. In ancient times, plants were recognized for their medicinal properties. Later, the arrival of synthetic drugs pushed it to the backstage. However, from being merely used for food, plants are now been widely e...

    Authors: Xavier Lieben Louis, Ryan Murphy, Sijo Joseph Thandapilly, Liping Yu and Thomas Netticadan
    Citation: BMC Complementary and Alternative Medicine 2012 12:140
    Content type: Research article Published on:

  25. Harpalycin 2 (HP-2) is an isoflavone isolated from the leaves of Harpalyce brasiliana Benth., a snakeroot found in northeast region of Brazil and used in folk medicine to treat snakebite. Its leaves are said to b...

    Authors: Rafael M Ximenes, Renata S Alves, Ticiana P Pereira, Renata M Araújo, Edilberto R Silveira, Marcelo M Rabello, Marcelo Z Hernandes, Veronica C G Soares, Daniel Bristot, Camila L Pires, Daniela O Toyama, Henrique H Gaeta, Helena S A Monteiro and Marcos H Toyama
    Citation: BMC Complementary and Alternative Medicine 2012 12:139
    Content type: Research article Published on:

  26. Doxorubicin (DOX) is an effective antineoplastic drug; however, clinical use of DOX is limited by its dose-dependent cardiotoxicity. It is well known that reactive oxygen species (ROS) play a vital role in the...

    Authors: Wen-Ching Wang, Yih-Huei Uen, Ming-Long Chang, Khoot-Peng Cheah, Joe-Sharg Li, Wen-Yu Yu, Kock-Chee Lee, Cheuk-Sing Choy and Chien-Ming Hu
    Citation: BMC Complementary and Alternative Medicine 2012 12:138
    Content type: Research article Published on:

  27. This study was to explore the effects of Gan-Lu-Yin (GLY) on the migration of vascular smooth muscle cells (VSMCs) induced by fetal bovine serum and on neointima formation in a rat model of carotid artery ball...

    Authors: Yi-Chung Chien, Ming-Jyh Sheu, Chieh-Hsi Wu, Wen-Hsin Lin, Ying-Yi Chen, Po-Liang Cheng and Hsu-Chen Cheng
    Citation: BMC Complementary and Alternative Medicine 2012 12:137
    Content type: Research article Published on:

  28. Psorospermun aurantiacum and Hypericum lanceolatum are plants locally used in Cameroon and other parts of Africa for the treatment of gastrointestinal and urinary tract infections, skin infections, venereal dise...

    Authors: Patricia D Tchakam, Paul K Lunga, Théodora K Kowa, Antoine Honoré N Lonfouo, Hippolyte K Wabo, Léon A Tapondjou, Pierre Tane and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2012 12:136
    Content type: Research article Published on:

  29. In this report, the isorhamnetin 3-o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, were evaluated for their ability to induce antioxidant and antigenotoxic effect...

    Authors: Jihed Boubaker, Mohammed Ben Sghaier, Ines Skandrani, Kamel Ghedira and Leila Chekir-Ghedira
    Citation: BMC Complementary and Alternative Medicine 2012 12:135
    Content type: Research article Published on:

  30. Our previous study had shown that P. amaryllifolius was able to selectively inhibit cell proliferation of hormone independent breast cancer cell line MDA-MB-231. To understand the mode of killing and mechanism of...

    Authors: Hueh Zan Chong, Swee Keong Yeap, Asmah Rahmat, Abdah Md Akim, Noorjahan Banu Alitheen, Fauziah Othman and Cheng Lian Gwendoline-Ee
    Citation: BMC Complementary and Alternative Medicine 2012 12:134
    Content type: Research article Published on:

  32. Despite high levels of clinically significant persistent cancer related fatigue in breast cancer survivors few treatments are currently available and most pose a significant burden on the part of the woman. Ac...

    Authors: Suzanna Maria Zick, Gwen Karilyn Wyatt, Susan Lynn Murphy, J Todd Arnedt, Ananda Sen and Richard Edmund Harris
    Citation: BMC Complementary and Alternative Medicine 2012 12:132
    Content type: Study protocol Published on:

  33. As complementary and alternative medicine (CAM) has developed extensively, uncertainty about the appropriateness of the terms CAM and other CAM-related terms has grown both in the research and practice communi...

    Authors: Isabelle Gaboury, Karine Toupin April and Marja Verhoef
    Citation: BMC Complementary and Alternative Medicine 2012 12:131
    Content type: Correspondence Published on:

  34. Utilization of herbal medicines in the preoperative period by Nigerian patients booked for day case surgery has not been explored.

    Authors: Tonia C Onyeka, Humphrey A Ezike, Ogochukwu M Nwoke, Emeka A Onyia, Elias C Onuorah, Samson U Anya and Timothy E Nnacheta
    Citation: BMC Complementary and Alternative Medicine 2012 12:130
    Content type: Research article Published on:

  35. Complementary and alternative medicine (CAM) is widely used for the treatment of infertility. While the Middle East and North Africa region has been shown to house one of the fastest growing markets of CAM pro...

    Authors: Ghina S Ghazeeri, Johnny T Awwad, Mohamad Alameddine, Zeina MH Younes and Farah Naja
    Citation: BMC Complementary and Alternative Medicine 2012 12:129
    Content type: Research article Published on:

  36. The leaves of Leea indica (Vitaceae), commonly known as ‘Huo Tong Shu’ in Malaysia, have been traditionally used as natural remedy in folk medicine by the locals. The current study reports the outcome of antioxid...

    Authors: Nidyaletchmy Subba Reddy, Suerialoasan Navanesan, Saravana Kumar Sinniah, Norhanom Abdul Wahab and Kae Shin Sim
    Citation: BMC Complementary and Alternative Medicine 2012 12:128
    Content type: Research article Published on:

  37. In Traditional Chinese Medicine (TCM), the lip diagnosis is an important diagnostic method which has a long history and is applied widely. The lip color of a person is considered as a symptom to reflect the ph...

    Authors: FuFeng Li, Changbo Zhao, Zheng Xia, Yiqin Wang, Xiaobo Zhou and Guo-Zheng Li
    Citation: BMC Complementary and Alternative Medicine 2012 12:127
    Content type: Technical advance Published on:

  38. Various medications of natural origin have effectively treated stress-related disorders, such as sleep disturbances and agitated conditions. The efficacy of Neurexan, a multicomponent, low-dose medication, has...

    Authors: Wilfried Dimpfel, Kerstin Roeska and Bernd Seilheimer
    Citation: BMC Complementary and Alternative Medicine 2012 12:126
    Content type: Research article Published on:

  39. Staphylococcus aureus is the pathogen most often and prevalently involved in skin and soft tissue infections. In recent decades outbreaks of methicillin-resistant S. aureus (MRSA) have created major problems for...

    Authors: Arunachalam Muthaiyan, Debabrata Biswas, Philip G Crandall, Brian J Wilkinson and Steven C Ricke
    Citation: BMC Complementary and Alternative Medicine 2012 12:125
    Content type: Research article Published on:

  40. A common side effect of oxaliplatin is peripheral neurotoxicity. Oxidative stress to dorsal root ganglion (DRG) may be one of important pathogenic mechanisms. Green tea contains four polyphenol catechins, whic...

    Authors: Jung Soo Lee, Yoon Tae Kim, Eun Kyoung Jeon, Hye Sung Won, Young-Seok Cho and Yoon Ho Ko
    Citation: BMC Complementary and Alternative Medicine 2012 12:124
    Content type: Research article Published on:

  41. In the field of acupuncture research, the topic of acupoint specificity has received increasing attention, but no unified conclusion has been reached on whether or not acupoint specificity exists. Furthermore,...

    Authors: Jie Yang, Fang Zeng, Yue Feng, Li Fang, Wei Qin, Xuguang Liu, Wenzhong Song, Hongjun Xie, Ji Chen and Fanrong Liang
    Citation: BMC Complementary and Alternative Medicine 2012 12:123
    Content type: Research article Published on:

  42. Appetite is intricately connected to eating behaviors and shows a high individual variability. In an attempt to approach the problem of gut hormone profiles, appetite, and eating behaviors at the individual le...

    Authors: Junhee Lee, Jiwon Lee, Hyunshang Shin, Ki-Suk Kim, Euiju Lee, Byunghee Koh and Hyeung-Jin Jang
    Citation: BMC Complementary and Alternative Medicine 2012 12:122
    Content type: Research article Published on:

  44. Sida acuta Burn f. and Sida cordifolia L. (Malvaceae) are traditionally used in Burkina Faso to treat several ailments, mainly pains, including abdominal infections and associated diseases. Despite the extensive...

    Authors: Kiessoun Konaté, Imaël Henri Nestor Bassolé, Adama Hilou, Raïssa RR Aworet-Samseny, Alain Souza, Nicolas Barro, Mamoudou H Dicko, Jacques Y Datté and Bertrand M’Batchi
    Citation: BMC Complementary and Alternative Medicine 2012 12:120
    Content type: Research article Published on:

  45. The fungus of Ganoderma is a traditional medicine in Asia with a variety of pharmacological functions including anti-cancer activities. We have purified an extracellular heteropolysaccharide fraction, PS-F2, from...

    Authors: Cheng-Li Wang, Chiu-Ying Lu, Chia-Chen Pi, Yu-Jing Zhuang, Ching-Liang Chu, Wen-Hsiung Liu and Chun-Jen Chen
    Citation: BMC Complementary and Alternative Medicine 2012 12:119
    Content type: Research article Published on:

  46. TS-1 is an oral anticancer drug containing a 5-fluorouracil derivative (Tegafur) that is widely used in Japan for the treatment of cancer, especially gastrointestinal tumors. Frequently, however, TS-1 therapy ...

    Authors: Kazuo Ogawa, Tatsushi Omatsu, Chinami Matsumoto, Naoko Tsuchiya, Masahiro Yamamoto, Yuji Naito and Toshikazu Yoshikawa
    Citation: BMC Complementary and Alternative Medicine 2012 12:118
    Content type: Research article Published on:

  47. In the present study, we examined the antioxidant effect of water soluble derivative of propolis (WSDP) and ethanolic (EEP) extract of propolis on renal and liver function in alloxan-induced diabetic mice. In ...

    Authors: Nada Oršolić, Damir Sirovina, Marijana Zovko Končić, Gordana Lacković and Gordana Gregorović
    Citation: BMC Complementary and Alternative Medicine 2012 12:117
    Content type: Research article Published on:

  48. Arctium lappa L. (Asteraceae), burdock, is a medicinal plant that is popularly used for treating hypertension, gout, hepatitis, and other inflammatory disorders. This study was performed to test the effect of et...

    Authors: Yun Jung Lee, Deok Ho Choi, Guk Hyun Cho, Jin Sook Kim, Dae Gill Kang and Ho Sub Lee
    Citation: BMC Complementary and Alternative Medicine 2012 12:116
    Content type: Research article Published on:

  49. This study aims to examine knowledge and attitudes towards Complementary and Alternative Medicine among medical students in Turkey, and find out whether they want to be trained in Complementary and Alternative...

    Authors: Hulya Akan, Guldal Izbirak, Elif Çiğdem Kaspar, Çiğdem Apaydin Kaya, Serpil Aydin, Nejat Demircan, P Gamze Bucaktepe, Cahit Özer, Hüseyin A Sahin and Osman Hayran
    Citation: BMC Complementary and Alternative Medicine 2012 12:115
    Content type: Research article Published on:

  50. Launaea procumbens (Asteraceae) is used as a folk medicine to treat hepatic disorders in Pakistan. The effect of a chloroform extract of Launaea procumbens (LPCE) was evaluated against carbon-tetrachloride (CCl4

    Authors: Rahmat A Khan, Muhammad R Khan, Mushtaq Ahmed, Sumaira Sahreen, Naseer A Shah, Mir Sadiq Shah, Jasia Bokhari, Umbreen Rashid, Bushra Ahmad and Shumaila Jan
    Citation: BMC Complementary and Alternative Medicine 2012 12:114
    Content type: Research article Published on:
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