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  1. Maytenus royleanus is traditionally used in gastro-intestinal disorders. The aim of this study was to evaluate the methanol extract of leaves and its derived fractions for various antioxidant assays and for its ...

    Authors: Maria Shabbir, Muhammad Rashid Khan and Naima Saeed
    Citation: BMC Complementary and Alternative Medicine 2013 13:143
    Content type: Research article Published on:

  2. The use of plants and their derived substances increases day by day for the discovery of therapeutic agents owing to their versatile applications. Current research is directed towards finding naturally-occurri...

    Authors: Shafiqul Islam, Samima Nasrin, Muhammad Ali Khan, ASM Sakhawat Hossain, Farhadul Islam, Proma Khandokhar, M Nurul Haque Mollah, Mamunur Rashid, Golam Sadik, Md Aziz Abdur Rahman and AHM Khurshid Alam
    Citation: BMC Complementary and Alternative Medicine 2013 13:142
    Content type: Research article Published on:

  3. Growing evidence shows that herb medicines have some anti-osteoporotic effects, the mechanism underlying is unknown. This study aims to investigate the therapeutic effect of Chinese herb supplements on rats th...

    Authors: Meijie Liu, Gary Guishan Xiao, Peijing Rong, Jiazi Dong, Zhiguo Zhang, Hongyan Zhao, Jingru Teng, Hongxia Zhao, Jinghua Pan, Yan Li, Qinglin Zha, Ying Zhang and Dahong Ju
    Citation: BMC Complementary and Alternative Medicine 2013 13:141
    Content type: Research article Published on:

  4. Stress caused by free radicals accumulation result into many hazardous diseases. A number of investigations are focusing to find out the plant oriented natural antioxidant moieties. The basic aim of this resea...

    Authors: Bushra Ahmad, Muhammad Rashid Khan, Naseer Ali Shah and Rahmat Ali Khan
    Citation: BMC Complementary and Alternative Medicine 2013 13:140
    Content type: Research article Published on:

  5. The purpose of this investigation was to determine if black tea extract (BTE), consisting primarily of flavanol compounds called theaflavins, could inhibit herpes simplex virus type-1 (HSV-1) infection in cult...

    Authors: Anthony Cantatore, Sade D Randall, Daniel Traum and Sandra D Adams
    Citation: BMC Complementary and Alternative Medicine 2013 13:139
    Content type: Research article Published on:

  6. Rubus fruticosus is used in tribal medicine as anthelmintic and an antispasmodic. In the current work, we investigated the anthelmintic and antispasmodic activities of crude methanol extract of fruits of R. frut...

    Authors: Niaz Ali, Umer Aleem, Syed Wadood Ali Shah, Ismail Shah, Muhammad Junaid, Ghayour Ahmed, Waqar Ali and Mehreen Ghias
    Citation: BMC Complementary and Alternative Medicine 2013 13:138
    Content type: Research article Published on:

  7. Soshiho-tang (SH; Chinese name, Xiao-Chai-Hu-Tang; Japanese name, Shosaiko-to) is a traditional Korean, Chinese, and Japanese medicine, which has been used to treat various conditions, including hepatitis, liv...

    Authors: Jung-Jin Lee, Taesoo Kim, Won-Kyung Cho and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:137
    Content type: Research article Published on:

  8. High-cholesterol diet (HCD) increases the oxidative stress in different tissues leading to many diseases. Rutin (RT) is a natural flavonoid (vitamin p), which possesses an antioxidant activity with protective ...

    Authors: Salem S Al-Rejaie, Abdulaziz M Aleisa, Mohamed M Sayed-Ahmed, Othman A AL-Shabanah, Hatem M Abuohashish, Mohammed M Ahmed, Khaled A Al-Hosaini and Mohamed M Hafez
    Citation: BMC Complementary and Alternative Medicine 2013 13:136
    Content type: Research article Published on:

  9. We have previously reported that aerial parts of Tylophora hirsuta have antispasmodic profile. The current work is an attempt for isolation of pharmacologically active compound(s) that contribute for its antispas...

    Authors: Niaz Ali
    Citation: BMC Complementary and Alternative Medicine 2013 13:135
    Content type: Research article Published on:

  10. Transcutaneous electrical nerve stimulation (TENS) is a non-pharmacologic treatment for pain relief. In previous animal studies, TENS effectively alleviated Complete Freund’s Adjuvant (CFA)- or carrageenan-ind...

    Authors: Jun-Fan Fang, Yi Liang, Jun-Ying Du and Jian-Qiao Fang
    Citation: BMC Complementary and Alternative Medicine 2013 13:134
    Content type: Research article Published on:

  11. The plant genus Fallopia is well-known in Chinese traditional medicine and includes many species that contain bioactive compounds, namely phytoestrogens. Consumption of phytoestrogens may be linked to decreased i...

    Authors: Jennifer C Brennan, Michael S Denison, Dirk M Holstege, Prokopios Magiatis, Jerry L Dallas, Elisa G Gutierrez, Anatoly A Soshilov and James R Millam
    Citation: BMC Complementary and Alternative Medicine 2013 13:133
    Content type: Research article Published on:

  12. Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great...

    Authors: Qihe Xu, Rudolf Bauer, Bruce M Hendry, Tai-Ping Fan, Zhongzhen Zhao, Pierre Duez, Monique SJ Simmonds, Claudia M Witt, Aiping Lu, Nicola Robinson, De-an Guo and Peter J Hylands
    Citation: BMC Complementary and Alternative Medicine 2013 13:132
    Content type: Review Published on:

  13. Women with polycystic ovary syndrome (PCOS) have symptoms of depression and anxiety and impaired health related quality of life (HRQoL). Here we test the post-hoc hypothesis that acupuncture and exercise impro...

    Authors: Elisabet Stener-Victorin, Göran Holm, Per Olof Janson, Deborah Gustafson and Margda Waern
    Citation: BMC Complementary and Alternative Medicine 2013 13:131
    Content type: Research article Published on:

  15. Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components. This study aims to investigate antibacterial activity of five varieties of Malaysian h...

    Authors: Mohd Izwan Zainol, Kamaruddin Mohd Yusoff and Mohd Yasim Mohd Yusof
    Citation: BMC Complementary and Alternative Medicine 2013 13:129
    Content type: Research article Published on:

  16. Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish e...

    Authors: Shan Deng, Bing Hu, Hong-Mei An, Qin Du, Ling Xu, Ke-Ping Shen, Xiu-Feng Shi, Meng-Meng Wei and Yang Wu
    Citation: BMC Complementary and Alternative Medicine 2013 13:128
    Content type: Research article Published on:

  17. Based on the reported antioxidant and anti-inflammatory potential of Terminalia paniculata, the bark aqueous extract (TPW) was investigated against liver damage.

    Authors: Sahil Talwar, Hitesh V Jagani, Pawan G Nayak, Nitesh Kumar, Anoop Kishore, Punit Bansal, Rekha R Shenoy and Krishnadas Nandakumar
    Citation: BMC Complementary and Alternative Medicine 2013 13:127
    Content type: Research article Published on:

  18. The TRAMIL program aims to understand, validate and expand health practices based on the use of medicinal plants in the Caribbean, which is a “biodiversity hotspot” due to high species endemism, intense develo...

    Authors: Claribel Luciano-Montalvo, Isabelle Boulogne and Jannette Gavillán-Suárez
    Citation: BMC Complementary and Alternative Medicine 2013 13:126
    Content type: Research article Published on:

  19. The aim of this publication is to present a case study of how to locate and appraise qualitative studies for the conduct of a meta-ethnography in the field of complementary and alternative medicine (CAM). CAM ...

    Authors: Brigitte Franzel, Martina Schwiegershausen, Peter Heusser and Bettina Berger
    Citation: BMC Complementary and Alternative Medicine 2013 13:125
    Content type: Correspondence Published on:

  20. Personalised (or individualised) medicine in the days of genetic researchrefers to molecular biologic specifications in individuals and not to aresponse to individual patient needs in the sense of person-centr...

    Authors: Brigitte Franzel, Martina Schwiegershausen, Peter Heusser and Bettina Berger
    Citation: BMC Complementary and Alternative Medicine 2013 13:124
    Content type: Research article Published on:

  21. Yi Guan Jian Decoction (YGJD), a famous Chinese prescription, has long been employed clinically to treat liver fibrosis. However, as of date, there is no report on the effects of YGJD from a metabonomic approa...

    Authors: Xiaojun Gou, Qing Tao, Qin Feng, Jinghua Peng, Yu Zhao, Jianye Dai, Wenyu Wang, Yongyu Zhang, Yiyang Hu and Ping Liu
    Citation: BMC Complementary and Alternative Medicine 2013 13:123
    Content type: Research article Published on:

  22. Patients’ expectations of osteopathic care have been little researched. The aim of this study was to quantify the most important expectations of patients in private UK osteopathic practices, and the extent to ...

    Authors: CM Janine Leach, Anne Mandy, Matthew Hankins, Laura M Bottomley, Vinette Cross, Carol A Fawkes, Adam Fiske and Ann P Moore
    Citation: BMC Complementary and Alternative Medicine 2013 13:122
    Content type: Research article Published on:

  23. Egyptians recognized the healing power of herbs and used them in their medicinal formulations. Nowadays, “Attarin” drug shops and the public use mainly the Unani medicinal system for treatment of their health ...

    Authors: Shereen K Ali, Ahmed R Hamed, Maha M Soltan, Usama M Hegazy, Esameldin E Elgorashi, Ibrahim A El-Garf and Ahmed A Hussein
    Citation: BMC Complementary and Alternative Medicine 2013 13:121
    Content type: Research article Published on:

  24. Parthenium hysterophorus L. (Asteraceae) is a common weed occurring throughout the globe. In traditional medicine its decoction has been used for treatment of many infectious and degenerative diseases. This work...

    Authors: Shashank Kumar, Amita Mishra and Abhay K Pandey
    Citation: BMC Complementary and Alternative Medicine 2013 13:120
    Content type: Research article Published on:

  25. A traditional Chinese Medicine (TCM) formula, HZJW, has been applied in clinics in China for gastrointestinal disorders. However, the therapeutic mechanism underlying its efficacy and safety remained to be def...

    Authors: Jian-Hui Xie, Yun-Long Chen, Qing-He Wu, Jun Wu, Ji-Yan Su, Hong-Yin Cao, Yu-Cui Li, Yi-Sheng Li, Jin-Bin Liao, Xiao-Ping Lai, Ping Huang and Zi-Ren Su
    Citation: BMC Complementary and Alternative Medicine 2013 13:119
    Content type: Research article Published on:

  26. Diabetes is a serious metabolic disorder affecting the metabolism of carbohydrate, protein and fat. A number of studies have shown that diabetes mellitus is associated with oxidative stress, leading to an incr...

    Authors: Hasni Misbah, Azlina Abdul Aziz and Norhaniza Aminudin
    Citation: BMC Complementary and Alternative Medicine 2013 13:118
    Content type: Research article Published on:

  27. Dental caries is an infectious disease which results from the acidic demineralisation of the tooth enamel and dentine as a consequence of the dental plaque (a microbial biofilm) accumulation. Research showed t...

    Authors: Caterina Signoretto, Anna Marchi, Anna Bertoncelli, Gloria Burlacchini, Alberto Milli, Francesco Tessarolo, Iole Caola, Adele Papetti, Carla Pruzzo, Egija Zaura, Peter Lingström, Itzhak Ofek, David A Spratt, Jonathan Pratten, Michael Wilson and Pietro Canepari
    Citation: BMC Complementary and Alternative Medicine 2013 13:117
    Content type: Research article Published on:

  28. Oxidative stress has been implicated in the progression of various diseases, which may result in the depletion of endogenous antioxidants. Exogenous supplementation with antioxidants could result in increased ...

    Authors: Werner Cordier, Mary Gulumian, Allan Duncan Cromarty and Vanessa Steenkamp
    Citation: BMC Complementary and Alternative Medicine 2013 13:116
    Content type: Research article Published on:

  29. Chromatin, residing in the nuclei of eukaryotic cells, comprises DNA and histones to make up chromosomes. Chromatin condenses to compact the chromosomes and loosens to facilitate gene transcription and DNA rep...

    Authors: Hsin-Ying Hsieh, Pei-Hsun Chiu and Sun-Chong Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:115
    Content type: Research article Published on:

  30. Reflexology is an alternative medical practice that produces beneficial effects by applying pressure to specific reflex areas. Our previous study suggested that reflexological stimulation induced cortical acti...

    Authors: Naoki Miura, Yuko Akitsuki, Atsushi Sekiguchi and Ryuta Kawashima
    Citation: BMC Complementary and Alternative Medicine 2013 13:114
    Content type: Research article Published on:

  31. Distressed individuals in Korea may benefit from the practice of mind–body exercises such as Qigong. However, the effectiveness of such techniques needs to be investigated.

    Authors: Eun-Young Hwang, Sun-Yong Chung, Jae-Heung Cho, Mi-Yeon Song, Sehyun Kim and Jong-Woo Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:113
    Content type: Research article Published on:

  32. Osteoclasts are primarily responsible for bone resorption. In many pathological bone diseases including osteoporosis and rheumatoid arthritis, osteoclasts are excessively activated. Thus, controlling of osteoc...

    Authors: Hyunil Ha, Ki-Shuk Shim, Hyosun An, Taesoo Kim and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:112
    Content type: Research article Published on:

  33. Plants of the genus Maytenus belong to the family Celastraceae and are widely used in folk medicine as anti-tumour, anti-asthmatic, analgesic, anti-inflammatory, antimicrobial and anti-ulcer agents, and as a trea...

    Authors: Tsholofelo Abednego Mokoka, Lyndy Joy McGaw, Ladislaus Kakore Mdee, Victor Patrick Bagla, Ezekiel Olugbenga Iwalewa and Jacobus Nicolaas Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:111
    Content type: Research article Published on:

  35. Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.

    Authors: Adelina Jiménez-Arellanes, Julieta Luna-Herrera, Ricardo Ruiz-Nicolás, Jorge Cornejo-Garrido, Amparo Tapia and Lilián Yépez-Mulia
    Citation: BMC Complementary and Alternative Medicine 2013 13:109
    Content type: Research article Published on:

  36. Traditional Japanese Medicine (Kampo) is often used in Japan, but very little data on its users are available. We investigated who uses Kampo, the reasons and opinions for its use.

    Authors: Lydia Hottenbacher, Thorolf ER Weißhuhn, Kenji Watanabe, Takashi Seki, Julia Ostermann and Claudia M Witt
    Citation: BMC Complementary and Alternative Medicine 2013 13:108
    Content type: Research article Published on:

  37. Teas from the husk fiber of Cocos nucifera are used in the folk medicine to treat arthritis and other inflammatory processes. Some works show that some varieties have biological activities. However, one of the ma...

    Authors: Rafaela Ribeiro Silva, Davi Oliveira e Silva, Humberto Rollemberg Fontes, Celuta Sales Alviano, Patricia Dias Fernandes and Daniela Sales Alviano
    Citation: BMC Complementary and Alternative Medicine 2013 13:107
    Content type: Research article Published on:

  38. Hwangryun-haedok-tang (HRT) is traditional herbal medicine used to treat inflammatory-related diseases in Asia. However, its effect on osteoclastogenesis and bone loss is still unknown. In this study, we evalu...

    Authors: Ki-Shuk Shim, Taesoo Kim, Hyunil Ha, Kwang Jin Lee, Chang-Won Cho, Han Sung Kim, Dong-Hyun Seo and Jin Yeul Ma
    Citation: BMC Complementary and Alternative Medicine 2013 13:106
    Content type: Research article Published on:

  39. Radiation-induced skin injury is a common complication of radiotherapy. The RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract (RCE) can ameliorate radiation-induced skin injury in our clinical observation. Bu...

    Authors: Xi-Jing Wang, Shuai Lin, Hua-Feng Kang, Zhi-Jun Dai, Ming-Hua Bai, Xiu-Long Ma, Xiao-Bin Ma, Meng-jie Liu, Xiao-Xu Liu and Bao-Feng Wang
    Citation: BMC Complementary and Alternative Medicine 2013 13:105
    Content type: Research article Published on:

  40. Diabetes remains a major health problem worldwide. Low-risk low-cost alternatives to pharmaceutical interventions are needed where lifestyle modifications have failed. We conducted a double-blind randomised pl...

    Authors: Suzanne J Grant, Dennis Hsu-Tung Chang, Jianxun Liu, Vincent Wong, Hosen Kiat and Alan Bensoussan
    Citation: BMC Complementary and Alternative Medicine 2013 13:104
    Content type: Research article Published on:

  41. Radiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage. We examined the protective effect of genistein in tumor-bearing mice after a...

    Authors: Tae Gen Son, Eun Ji Gong, Min Ji Bae, Sung Dae Kim, Kyu Heo, Changjong Moon, Kwangmo Yang and Joong Sun Kim
    Citation: BMC Complementary and Alternative Medicine 2013 13:103
    Content type: Research article Published on:

  42. Like any other form of healthcare, acupuncture takes place in a particular context which can enhance or diminish treatment outcomes (i.e. can produce contextual effects). Patients’ expectations of acupuncture ...

    Authors: Felicity L Bishop and George T Lewith
    Citation: BMC Complementary and Alternative Medicine 2013 13:102
    Content type: Research article Published on:

  43. Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic act...

    Authors: Muhammad Mutassim Billah, Rafikul Islam, Hajera Khatun, Shahnaj Parvin, Ekramul Islam, SM Anisul Islam and Akbar Ali Mia
    Citation: BMC Complementary and Alternative Medicine 2013 13:101
    Content type: Research article Published on:

  44. Microbial infections and resulting inflammation and oxidative stress are common pathogenesis of gastrointestinal tract (GIT) disorders. In South Africa, several species of the genus Maytenus are used in tradition...

    Authors: Aroke Shahid Ahmed, Lyndy J McGaw and Jacobus N Eloff
    Citation: BMC Complementary and Alternative Medicine 2013 13:100
    Content type: Research article Published on:

  45. The aims of this study were to evaluate the antioxidant activity and to identify the antioxidant components of a traditional Chinese medicine formula consisting of a combination of Shanzha (the fruit of Crataegus...

    Authors: Cheng-Yu Chen, Hua Li, Ya-Nan Yuan, Hui-Qing Dai and Bin Yang
    Citation: BMC Complementary and Alternative Medicine 2013 13:99
    Content type: Research article Published on:

  46. Anemia is a condition that has multiple origins. One such origin is the destruction of red blood cells’ (RBCs) membrane induced by free radicals. Treatment of anemia could therefore be enhanced by the use of f...

    Authors: Prosper Cabral Nya Biapa, Horea Matei, Ştefana Bâlici, Julius Eyong Oben and Jeanne Yonkeu Ngogang
    Citation: BMC Complementary and Alternative Medicine 2013 13:98
    Content type: Research article Published on:

  47. St. John’s wort (Hypericum perforatum L.) is an herbaceous plant that is native to Europe, West Asia and North Africa and that is recognized and used worldwide for the treatment of mild and moderate depression. I...

    Authors: Ana Paula Peron, Rosinete Gonçalves Mariucci, Igor Vivian de Almeida, Elisângela Düsman, Mário Sérgio Mantovani and Veronica Elisa Pimenta Vicentini
    Citation: BMC Complementary and Alternative Medicine 2013 13:97
    Content type: Research article Published on:

  48. The current work is an attempt to know about additional chemical profile of Artemisia macrocephala. Antioxidant activity is performed as the plant is reported to contain flavonoids, which have antioxidant activit...

    Authors: Niaz Ali, Ismail Shah, Syed Wadood Ali Shah, Ghayour Ahmed, Mohammad Shoaib, Muhammad Junaid, Waqar Ali and Zahoor Ahmed
    Citation: BMC Complementary and Alternative Medicine 2013 13:96
    Content type: Research article Published on:

  49. During the last decades, the number of people suffering from dermatophytoses has seriously increased, mainly due to the development of resistant strains of microorganisms to a range of formally efficient antib...

    Authors: Guy Sedar Singor Njateng, Donatien Gatsing, Raymond Simplice Mouokeu, Paul Keilah Lunga and Jules-Roger Kuiate
    Citation: BMC Complementary and Alternative Medicine 2013 13:95
    Content type: Research article Published on:

  50. Some Ficus species have been used in traditional African medicine in the treatment of diabetes. The antidiabetic potential of certain species has been confirmed in vivo but the mechanism of activity remains uncer...

    Authors: Oyinlola O Olaokun, Lyndy J McGaw, Jacobus N Eloff and Vinny Naidoo
    Citation: BMC Complementary and Alternative Medicine 2013 13:94
    Content type: Research article Published on:
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