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  1. Integrative medicine (IM) is a patient-centered, healing-oriented clinical paradigm that explicitly includes all appropriate therapeutic approaches whether they originate in conventional or complementary medic...

    Authors: Patricia M Herman, Sally E Dodds, Melanie D Logue, Ivo Abraham, Rick A Rehfeld, Amy J Grizzle, Terry F Urbine, Randy Horwitz, Robert L Crocker and Victoria H Maizes
    Citation: BMC Complementary and Alternative Medicine 2014 14:132
    Content type: Study protocol Published on:

  2. In a large randomised trial in patients with seasonal allergic rhinitis (SAR), acupuncture was superior compared to sham acupuncture and rescue medication. The aim of this paper is to describe the characterist...

    Authors: Miriam Ortiz, Claudia M Witt, Sylvia Binting, Cornelia Helmreich, Josef Hummelsberger, Florian Pfab, Michael Wullinger, Dominik Irnich, Klaus Linde, Bodo Niggemann, Stefan N Willich and Benno Brinkhaus
    Citation: BMC Complementary and Alternative Medicine 2014 14:128
    Content type: Research article Published on:

  3. Angiopoietin (Ang) is one of the major effectors of angiogenesis, playing a critical role in neurovascular remodeling after stroke. Acupuncture has been widely used for treating stroke in China for a long time...

    Authors: Hua-Jun Zhou, Tao Tang, Jian-Hua Zhong, Jie-Kun Luo, Han-Jin Cui, Qi-Mei Zhang, Jing-Hua Zhou and Qiang Zhang
    Citation: BMC Complementary and Alternative Medicine 2014 14:127
    Content type: Research article Published on:

  4. The effects of high and low jumping exercise intensities combined with honey on bone and gonadotrophins were investigated in eighty four 9 week-old female rats.

    Authors: Maryam Mosavat, Foong Kiew Ooi and Mahaneem Mohamed
    Citation: BMC Complementary and Alternative Medicine 2014 14:126
    Content type: Research article Published on:

  5. Cancer has become a global public health problem and the search for new control measures is urgent. Investigation of plant products such as essential oils from Monodora myristica, Xylopia aethiopica and Xylopia p...

    Authors: Issakou Bakarnga-Via, Jean Baptiste Hzounda, Patrick Valere Tsouh Fokou, Lauve Rachel Yamthe Tchokouaha, Magali Gary-Bobo, Audrey Gallud, Marcel Garcia, Lucain Walbadet, Youssouf Secka, Pierre Michel Jazet Dongmo, Fabrice Fekam Boyom and Chantal Menut
    Citation: BMC Complementary and Alternative Medicine 2014 14:125
    Content type: Research article Published on:

  6. The use of complementary alternative medicine (CAM) is potentially prevalent among paediatric patients with chronic diseases but with variable rates among different age groups, diseases and countries. There ar...

    Authors: Pauliina Nousiainen, Laura Merras-Salmio, Kristiina Aalto and Kaija-Leena Kolho
    Citation: BMC Complementary and Alternative Medicine 2014 14:124
    Content type: Research article Published on:

  7. Dicranopteris linearis (family Gleicheniaceae) has been reported to possess anti-inflammatory and antioxidant activities but no attempt has been made to study its hepatoprotective potential. The aim of the prese...

    Authors: Farah Hidayah Kamisan, Farhana Yahya, Siti Syariah Mamat, Mohamad Fauzi Fahmi Kamarolzaman, Norhafizah Mohtarrudin, Teh Lay Kek, Mohd Zaki Salleh, Mohd Khairi Hussain and Zainul Amiruddin Zakaria
    Citation: BMC Complementary and Alternative Medicine 2014 14:123
    Content type: Research article Published on:

  8. Present investigation deals with antimicrobial screening of ten medicinally important plants used by the inhabitants of district Haripur, Khyber Pakhtunkhwa (KPK) for different infectious diseases.

    Authors: Nadeem Khan, Arshad Mehmood Abbasi, Ghulam Dastagir, Abdul Nazir, Ghulam Mujtaba Shah, Mohammad Maroof Shah and Munir H Shah
    Citation: BMC Complementary and Alternative Medicine 2014 14:122
    Content type: Research article Published on:

  9. This research evaluated the genotoxicity of oil and tincture of H. annuus L. seeds using the micronucleus assay in bone marrow of mice. The interaction between these preparations and the genotoxic effects of doxo...

    Authors: Marcelo Fabiano Gomes Boriollo, Luiz Silva Souza, Marielly Reis Resende, Thaísla Andrielle da Silva, Nelma de Mello Silva Oliveira, Maria Cristina Costa Resck, Carlos Tadeu dos Santos Dias and João Evangelista Fiorini
    Citation: BMC Complementary and Alternative Medicine 2014 14:121
    Content type: Research article Published on:

  10. Blue light is a high-energy or short-wavelength visible light, which induces retinal diseases such as age-related macular degeneration and retinitis pigmentosa. Bilberry (Vaccinium myrtillus L.) and lingonberry (

    Authors: Kenjirou Ogawa, Yoshiki Kuse, Kazuhiro Tsuruma, Saori Kobayashi, Masamitsu Shimazawa and Hideaki Hara
    Citation: BMC Complementary and Alternative Medicine 2014 14:120
    Content type: Research article Published on:

  11. The miswak (Salvadora persica) is a natural toothbrush. It is well known that very little information has been reported on enzymes in miswak as medicinal plant. Recently, we study peroxidase in miswak. In the pre...

    Authors: Saleh A Mohamed, Yaaser Q Almulaiky, Youssri M Ahmed, Omar AM Al-Bar and Ibrahim H Ibrahim
    Citation: BMC Complementary and Alternative Medicine 2014 14:119
    Content type: Research article Published on:

  12. The purpose of this study was to investigate the inhibitory effects of long-term electroacupuncture at BaiHui (DU20) and ZuSanLi (ST36) on cardiovascular remodeling in spontaneously hypertensive rats (SHR) and...

    Authors: Ze-Jun Huo, Quan Li, Gui-Hua Tian, Chang-Man Zhou, Xiao-Hong Wei, Chun-Shui Pan, Lei Yang, Yan Bai, You-Yi Zhang, Ke He, Chuan-She Wang, Zhi-Gang Li and Jing-Yan Han
    Citation: BMC Complementary and Alternative Medicine 2014 14:118
    Content type: Research article Published on:

  13. African trypanosomiasis is a major disease of economic and public health importance affecting agricultural and human development. The search for alternative compounds against African trypanosomiasis is justifi...

    Authors: Teka Feyera, Getachew Terefe and Workineh Shibeshi
    Citation: BMC Complementary and Alternative Medicine 2014 14:117
    Content type: Research article Published on:

  14. Stellera chamaejasme L, a traditional Chinese herb, has long been used for treatment of various tumors in the Chinese population. In our previous study, we paid an attention to the cytotoxic and proapoptotic eff...

    Authors: Xiaoni Liu, Qing Yang, Ganlin Zhang, Yujie Li, Ying Chen, Xiaogang Weng, Yajie Wang, Yiwei Wang and Xiaoxin Zhu
    Citation: BMC Complementary and Alternative Medicine 2014 14:116
    Content type: Research article Published on:

  15. Complementary and alternative medicine is often used by patients with malignant glioma. Although several interactions of various alternative agents with chemotherapy are known, none has been described for temo...

    Authors: Thomas Melchardt, Teresa Magnes, Lukas Weiss, Michael Grundbichler, Michael Strasser, Clemens Hufnagl, Martin Moik, Richard Greil and Alexander Egle
    Citation: BMC Complementary and Alternative Medicine 2014 14:115
    Content type: Case report Published on:

  16. There are a number of dietary components that may prove useful in the prevention and treatment of cancer. In some cultures, fenugreek seeds are used to treat cancer. The current study focuses on the anticancer...

    Authors: Abdulaziz Alsemari, Fahad Alkhodairy, Ahmad Aldakan, Mai Al-Mohanna, Eman Bahoush, Zakia Shinwari and Ayodele Alaiya
    Citation: BMC Complementary and Alternative Medicine 2014 14:114
    Content type: Research article Published on:

  17. According to the World Health Organization (WHO), reproductive health problems are the leading cause of morbidity and mortality for women in Africa. In spite of this scenario and the importance of plants in Af...

    Authors: Alexandra M Towns and Tinde van Andel
    Citation: BMC Complementary and Alternative Medicine 2014 14:113
    Content type: Research article Published on:

  18. Solanum xanthocarpum (Solanaceae) has been used for treatment of many infectious and degenerative diseases in traditional medicine. Present study reports the medicinal efficacy of S. xanthocarpum fruit as antiox...

    Authors: Shashank Kumar and Abhay K Pandey
    Citation: BMC Complementary and Alternative Medicine 2014 14:112
    Content type: Research article Published on:

  19. cis-Diammineplatinum (II) dichloride (cisplatin) is the important anti-cancer agent useful in treatment of various cancers. Unfortunately, it can produce unwanted side effects in various tissues, including the l...

    Authors: Sarawoot Palipoch, Chuchard Punsawad, Phanit Koomhin and Prasit Suwannalert
    Citation: BMC Complementary and Alternative Medicine 2014 14:111
    Content type: Research article Published on:

  20. Ruscogenin is a major steroid sapogenin in the traditional Chinese herb Ophiopogon japonicus that have multiple bioactivities. Recent studies have demonstrated that ruscogenin is involved in down-regulation of...

    Authors: Hung-Jen Lu, Thing-Fong Tzeng, Shorong-Shii Liou, Sheng Da Lin, Ming-Chang Wu and I-Min Liu
    Citation: BMC Complementary and Alternative Medicine 2014 14:110
    Content type: Research article Published on:

  21. Activation of the Wnt pathway is known to promote tumorigenesis and tumor metastasis, and targeting Wnt pathway inhibition has emerged as an attractive approach for controlling tumor invasion and metastasis. T...

    Authors: Song Yi Park, Yun-Kyoung Lee, Won Sup Lee, Ock Jin Park and Young-Min Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:109
    Content type: Research article Published on:

  22. The interaction between ionizing radiation and substances in cells will induce the production of free radicals. These free radicals inflict damage to important biomolecules such as chromosomes, proteins and li...

    Authors: Tengku Ahbrizal Farizal Tengku Ahmad, Faizul Jaafar, Zakiah Jubri, Khairuddin Abdul Rahim, Nor Fadilah Rajab and Suzana Makpol
    Citation: BMC Complementary and Alternative Medicine 2014 14:108
    Content type: Research article Published on:

  23. Gastrodia elata Blume (GEB), commonly used medicinal herb, has been reported as a promising candidate for neurodegenerative diseases such as Parkinson’s disease. The dopamine precursor, L-3,4-dihydroxyphenylal...

    Authors: Ah-Reum Doo, Seung-Nam Kim, Dae-Hyun Hahm, Hye Hyun Yoo, Ji-Yeun Park, Hyejung Lee, Songhee Jeon, Jongpil Kim, Seong-Uk Park and Hi-Joon Park
    Citation: BMC Complementary and Alternative Medicine 2014 14:107
    Content type: Research article Published on:

  24. The Malaysian Tualang honey (TH) is not only cytotoxic to human breast cancer cell lines but it has recently been reported to promote the anticancer activity induced by tamoxifen in MCF-7 and MDA-MB-231 cells sug...

    Authors: Nik Soriani Yaacob and Nur Faezah Ismail
    Citation: BMC Complementary and Alternative Medicine 2014 14:106
    Content type: Research article Published on:

  25. There has been a global rise in the use of natural health products (NHPs). Proper regulation of NHPs is pivotal to ensure good quality control standards, enhance consumers' safety and facilitate their integrat...

    Authors: Abdelmoneim Awad and Dana Al-Shaye
    Citation: BMC Complementary and Alternative Medicine 2014 14:105
    Content type: Research article Published on:

  26. Gelsemium sempervirens L. (Gelsemium s.) is a traditional medicinal plant, employed as an anxiolytic at ultra-low doses and animal models recently confirmed this activity. However the mechanisms by which it migh...

    Authors: Marta Marzotto, Debora Olioso, Maurizio Brizzi, Paola Tononi, Mirco Cristofoletti and Paolo Bellavite
    Citation: BMC Complementary and Alternative Medicine 2014 14:104
    Content type: Research article Published on:

  27. Race has been reported to affect the use of complementary and alternative medicine (CAM), but there is very little research on the use of CAM by ethnicity in Korea. This study explores the prevalence of CAM us...

    Authors: Jung Hye Hwang, Dong Woon Han, Eun Kyung Yoo and Woon-Yong Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:103
    Content type: Research article Published on:

  28. In our previous studies conducted on Ardisia crispa roots, it was shown that Ardisia crispa root inhibited inflammation-induced angiogenesis in vivo. The present study was conducted to identify whether the anti-a...

    Authors: Dayang Erna Zulaikha Awang Hamsin, Roslida Abdul Hamid, Latifah Saiful Yazan, Che Norma Mat Taib and Looi Ting Yeong
    Citation: BMC Complementary and Alternative Medicine 2014 14:102
    Content type: Research article Published on:

  29. Poria cocos Wolf, a medicinal fungus, is widely used in traditional medicines in East Asian countries owing to its various therapeutic potentials. Although several studies have demonstrated the anti-inflammatory...

    Authors: Jin-Woo Jeong, Hye Hyeon Lee, Min Ho Han, Gi-Young Kim, Su Hyun Hong, Cheol Park and Yung Hyun Choi
    Citation: BMC Complementary and Alternative Medicine 2014 14:101
    Content type: Research article Published on:

  30. Artemisia capillaries Thunb. (AC) has been used to treat inflammatory and hepatic disorders such as hepatic injury, hepatic fibrosis and hepatitis. However, the efficacy of AC against atopic dermatitis (AD), an ...

    Authors: Hyekyung Ha, Hoyoung Lee, Chang Seob Seo, Hye-Sun Lim, Jun Kyoung Lee, Mee-Young Lee and Hyeunkyoo Shin
    Citation: BMC Complementary and Alternative Medicine 2014 14:100
    Content type: Research article Published on:

  31. Salvia africana-lutea L., an important medicinal sage used in the Western Cape (South Africa), can be termed a ‘broad-spectrum remedy’ suggesting the presence of a multiplicity of bioactive metabolites. This stu...

    Authors: Mpumelelo M Nkomo, David DR Katerere, Hester HF Vismer, Thomas T Cruz, Stephane S Balayssac, Myriam M Malet-Martino and Nokwanda NP Makunga
    Citation: BMC Complementary and Alternative Medicine 2014 14:99
    Content type: Research article Published on:

  32. Fumaria parviflora Lam. (Fumaraceae) is widely used in traditional as well as folkloric system of medicine from ancient. It is commonly known as ‘Pitpapra’ or ‘Shahtrah’ in Indian traditional system of medicine ...

    Authors: Mohammad Jameel, Mohammad Islamuddin, Abuzer Ali, Farhat Afrin and Mohammed Ali
    Citation: BMC Complementary and Alternative Medicine 2014 14:98
    Content type: Research article Published on:

  33. Snail transcription factor can induce epithelial-mesenchymal transition (EMT), associated with decreased cell adhesion-associated molecules like E-cadherin, increased mesenchymal markers like vimentin, leading...

    Authors: Liza J Burton, Petrina Barnett, Basil Smith, Rebecca S Arnold, Tamaro Hudson, Kousik Kundu, Niren Murthy and Valerie A Odero-Marah
    Citation: BMC Complementary and Alternative Medicine 2014 14:97
    Content type: Research article Published on:

  34. Acupuncture is a therapy that involves applying mechanical stimulation to acupoints using needles. Although acupuncture is believed to trigger neural regulation by opioids or adenosine, still little is known a...

    Authors: Shu-Yih Wu, Wei-Hsin Chen, Ching-Liang Hsieh and Yi-Wen Lin
    Citation: BMC Complementary and Alternative Medicine 2014 14:96
    Content type: Research article Published on:

  35. Major depressive disorder (MDD) is the leading cause of disability in the developed world, yet broadly effective treatments remain elusive. Up to 40% of patients with depression are unresponsive to at least tw...

    Authors: Stuart J Eisendrath, Erin P Gillung, Kevin L Delucchi, Maggie Chartier, Daniel H Mathalon, Jude C Sullivan, Zindel V Segal and Mitchell D Feldman
    Citation: BMC Complementary and Alternative Medicine 2014 14:95
    Content type: Study protocol Published on:

  36. M. Suaveolens Ledeb has long been used in China to treat inflammatory infectious diseases. Melilotus is extracted from Melilotus Suaveolens Ledeb and its therapeutic potential is associated with its anti-inflamm...

    Authors: Ming-wei Liu, Mei-xian Su, Yun-hui Wang, Wei Wei, Lan-fang Qin, Xu Liu, Mao-li Tian and Chuan-yun Qian
    Citation: BMC Complementary and Alternative Medicine 2014 14:94
    Content type: Research article Published on:

  38. This study was designed to evaluate the effects of electroacupuncture-like stimulation at Baihui (GV20) and Dazhui (GV14) acupoints (EA at acupoints) following mild cerebral ischemia-reperfusion (I/R) injury. ...

    Authors: Chin Yi Cheng, Jaung Geng Lin, Shan Yu Su, Nou Ying Tang, Shung Te Kao and Ching Liang Hsieh
    Citation: BMC Complementary and Alternative Medicine 2014 14:92
    Content type: Research article Published on:

  39. Chinese herbal medicine (CHM) has been commonly used for treating osteoarthritis in Asia for centuries. This study aimed to conduct a large-scale pharmaco-epidemiologic study and evaluate the frequency and pat...

    Authors: Fang-Pey Chen, Ching-Mao Chang, Shinn-Jang Hwang, Yu-Chun Chen and Fun-Jou Chen
    Citation: BMC Complementary and Alternative Medicine 2014 14:91
    Content type: Research article Published on:

  40. Water soluble cinnamon extract has been shown to increase insulin sensitivity and modulate macrophage activation, a desirable trait for the management of obesity or atherosclerosis. Our present study investiga...

    Authors: Hee Kang, Sung-Hyun Park, Jeong-Moon Yun, Tae-Gyu Nam, Young-Eun Kim, Dae-Ok Kim and Youn Jung Kim
    Citation: BMC Complementary and Alternative Medicine 2014 14:90
    Content type: Research article Published on:

  41. Berberine is an isoquinoline alkaloid mainly extracted from Rhizoma Coptidis and has been shown to possess a potent inhibitory activity against bacterial. However, the role of berberine in anti-bacterial action h...

    Authors: Ming Chu, Ran Ding, Zheng-yun Chu, Ming-bo Zhang, Xiao-yan Liu, Shao-hua Xie, Yan-jun Zhai and Yue-dan Wang
    Citation: BMC Complementary and Alternative Medicine 2014 14:89
    Content type: Research article Published on:

  42. Alzheimer’s disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) is a key enzyme responsible for amyloid plaque production, which implic...

    Authors: Xue Wang, Jun-Ran Kim, Seong-Baek Lee, Young-Joon Kim, Moon Young Jung, Hyung-Wook Kwon and Young-Joon Ahn
    Citation: BMC Complementary and Alternative Medicine 2014 14:88
    Content type: Research article Published on:

  43. Artemisia nilagirica (Asteraceae) and Murraya koenigii (Rutaceae) are widely distributed in eastern region of India. Leaves of Artemisia nilagirica plant are used to treat cold and cough by the local tribal popu...

    Authors: Sumanta Kumar Naik, Soumitra Mohanty, Avinash Padhi, Rashmirekha Pati and Avinash Sonawane
    Citation: BMC Complementary and Alternative Medicine 2014 14:87
    Content type: Research article Published on:

  44. Radix Trichosanthis (RT), the dry root tuber of Trichosanthis kirilowii Maxim (Cucurbitaceae), is a traditional Chinese medicine. Although a wide range of saponin pharmacological properties has been identified, t...

    Authors: Ying Chen, Yonghong Miao, Liyong Huang, Juxiang Li, Haiyan Sun, Yuanzeng Zhao, Jing Yang and Wenke Zhou
    Citation: BMC Complementary and Alternative Medicine 2014 14:86
    Content type: Research article Published on:

  45. The National Institutes of Health reported in 2007 that approximately 38% of United States adults have used at least one type of Complementary and Alternative Medicine (CAM). There are no studies available tha...

    Authors: Lisa Strouss, Amy Mackley, Ursula Guillen, David A Paul and Robert Locke
    Citation: BMC Complementary and Alternative Medicine 2014 14:85
    Content type: Research article Published on:

  46. In tuberculosis (TB), the steadily increasing bacterial resistance to existing drugs and latent TB continue to be major concerns. A combination of conventional drugs and plant derived therapeutics can serve to...

    Authors: Pooja Gupta, Purva Bhatter, Desiree D’souza, Monica Tolani, Poonam Daswani, Pundarikakshudu Tetali and Tannaz Birdi
    Citation: BMC Complementary and Alternative Medicine 2014 14:84
    Content type: Research article Published on:

  47. Cyperus rotundus Linn. (Cyperaceae) is used to treat inflammation, pain, fever, wounds, boils and blisters in folk medicine. This study evaluated the antinociceptive effect of the hydromethanol extract of whole ...

    Authors: Mohammad Zafar Imam and Chandra Datta Sumi
    Citation: BMC Complementary and Alternative Medicine 2014 14:83
    Content type: Research article Published on:

  48. An embryonic toxicity of Rhizoma sparganii was observed in mice. This study was aimed to evaluate the anticancer effects of ...

    Authors: Jun-Wu Zhang and Ya-Hui Wei
    Citation: BMC Complementary and Alternative Medicine 2014 14:82
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Complementary and Alternative Medicine 2017 17:260

  49. Hydrogen has been reported to relieve damage in many disease models, and is a potential additive in drinking water to provide protective effects for patients as several clinical studies revealed. However, the ...

    Authors: Jinling Xue, Guodong Shang, Yoshinori Tanaka, Yasuhiro Saihara, Lingyan Hou, Natalia Velasquez, Wenjun Liu and Yun Lu
    Citation: BMC Complementary and Alternative Medicine 2014 14:81
    Content type: Research article Published on:

  50. Dai Huang Fu Zi Tang (DHFZT), an oriental herbal formula, has long been used clinically in treatment of intestinal obstruction, acute pancreatitis, cholecystalgia and chronic diarrhea for thousands of years. R...

    Authors: Xiaoguang Lu, Xin Kang, Libin Zhan, Chunyu Lv, Zhiwei Fan, Yingli Wang, Robbie Ali, Chang Lv, Siyao Li and Jinhai Mu
    Citation: BMC Complementary and Alternative Medicine 2014 14:80
    Content type: Research article Published on:
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