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  1. Traditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treat...

    Authors: Haibo Hu, Yanfang Yang, Abdallah Aissa, Volkan Tekin, Jialin Li, Sujogya Kumar Panda, Hao Huang and Walter Luyten
    Citation: BMC Complementary Medicine and Therapies 2022 22:244
  2. Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a health-promoting medicinal food The objective of the present study is to evaluate the anti-as...

    Authors: Kyung Hee Lee, Yeo Jin Jang, Woon Sang Hwang, Ki Sun Kwon, Wha Young Lee, Jeanman Kim, Sung Phil Kim and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2022 22:242
  3. Osteoporosis, a skeletal disease described by impaired bone strength, cause an increased risk of fractures. We aimed in this study to clarify which particular wise combination of probiotics has the most benefi...

    Authors: Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Farhad Koohpeyma, Pedram Talezadeh and Nima Montazeri-Najafabady
    Citation: BMC Complementary Medicine and Therapies 2022 22:241
  4. To curb the spread of the first wave of the COVID-19 pandemic, the Swiss government declared a state of health emergency and ordered a legal restriction concerning the opening of healthcare institutions. In th...

    Authors: Angélique Bourqui, Pierre-Yves Rodondi, Emna El May and Julie Dubois
    Citation: BMC Complementary Medicine and Therapies 2022 22:240
  5. Cervical cancer remains one of the significant causes of mortality in women due to the limitations of current treatment strategies and their associated side effects. Investigation of alternative medicine, incl...

    Authors: Saurav Kumar, Vaishali Mulchandani and Jayasri Das Sarma
    Citation: BMC Complementary Medicine and Therapies 2022 22:239
  6. There is paucity of data regarding effects of guided meditation (Yoganidra) on quality of life among patients of chronic kidney disease on maintenance hemodialysis. Our objective was to study effects of guided...

    Authors: Bhalendu S. Vaishnav, Jekishan Jayeshbhai Hirapara and Maulin K. Shah
    Citation: BMC Complementary Medicine and Therapies 2022 22:238
  7. Canadians seeking medical cannabis (MC) may encounter difficulties in finding a healthcare provider (HCP) who authorizes their access to it. Barriers that HCPs face in authorizing MC are unclear. The objective...

    Authors: Yasmina Hachem, Sara J. Abdallah, Sergio Rueda, Jessica L. Wiese, Kamna Mehra, Jennifer Rup, Juthaporn Cowan, Antonio Vigano and Cecilia T. Costiniuk
    Citation: BMC Complementary Medicine and Therapies 2022 22:237
  8. This article has been retracted. Please see the Retraction Notice for more detail: 10.1186/s12906-015-0733-1

    Authors: Cheng Liu, Xia Yuan, Le Tao, Zhuoan Cheng, Xiuqin Dai, Xia Sheng and Dongying Xue
    Citation: BMC Complementary Medicine and Therapies 2022 22:236
  9. Lysiphyllum strychnifolium (Craib) A. Schmitz, a traditional Thai medicinal plant, is mainly composed of polyphenols and flavonoids and exhibits several pharmacological activities, including antioxidant, anticanc...

    Authors: Kunwadee Noonong, Kanta Pranweerapaiboon, Kulathida Chaithirayanon, Kantamat Surayarn, Phicharinee Ditracha, Narin Changklungmoa, Pornanan Kueakhai, Poonsit Hiransai and Kingkan Bunluepuech
    Citation: BMC Complementary Medicine and Therapies 2022 22:235
  10. The COVID-19 pandemic lockdown has had a profound impact on physical and mental well-being throughout the world. Previous studies have revealed that complementary and alternative medicine (CAM) is frequently u...

    Authors: Agnete Egilsdatter Kristoffersen, Miek C. Jong, Johanna Hök Nordberg, Esther T. van der Werf and Trine Stub
    Citation: BMC Complementary Medicine and Therapies 2022 22:234
  11. The plant-based medicinal food (PBMF) is a functional compound extracted from 6 medicinal and edible plants: Coix seed, L. edodes, A. officinalis L., H. cordata, Dandelion, and G. frondosa. Our previous studies h...

    Authors: Lin Tian, Xuxi Chen, Li Cao, Lishi Zhang and Jinyao Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:233
  12. Chronic ultraviolet (UV) exposure is one of the major external factors in skin aging, and repetitive UVB exposure induces extracellular matrix (ECM) damage as well as metabolic disease. Alpinia officinarum Rhizom...

    Authors: Jong Min Jung, Oh Yun Kwon, Jong Kyu Choi and Seung Ho Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:232
  13. Epilepsy induces behavioral effects and histological changes in the hippocampus. Eugenol, the main component of clove essential oil, has modulatory effects on seizure. We aimed to investigate the effect of int...

    Authors: Fatemeh Parvizi, Soraya Mehrabi, Ayeh Naghizadeh, Mohammad Kamalinejad‬, Sepide Goudarzi and ‬‬‬‬‬‬‬‬‬‬ Maryam Farahmandfar
    Citation: BMC Complementary Medicine and Therapies 2022 22:231
  14. Authors: León F. Villegas Vílchez, Julio Hidalgo Ascencios and Thomas P. Dooley
    Citation: BMC Complementary Medicine and Therapies 2022 22:230

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:62

  15. The aim of this study is investigate the antimicrobial effect of plant oils against bacterial strains isolated from neonatal asymptomatic bacteriuria (ABU) and to evaluate the antiseptic effect of the most pot...

    Authors: Rasha H. Bassyouni, Zeinat Kamel, Alkassem Ahmed Algameel, Ghada Ismail and Sylvana N. Gaber
    Citation: BMC Complementary Medicine and Therapies 2022 22:229
  16. Honey has broad spectrum antibacterial activity against clinically important organisms and may be suitable for treating superficial bacterial infections. However, very little data are available describing pote...

    Authors: Brayden H. Gray, Kathryn J. Green, Robbie R. Haines and Katherine A. Hammer
    Citation: BMC Complementary Medicine and Therapies 2022 22:228
  17. Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular ...

    Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El-Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:227
  18. Delay in episiotomy wound healing can lead to infection. The application of natural antimicrobial agents isolated from herbal essences can be a good strategy to prevent the growth of bacteria and promote the w...

    Authors: Fatemeh Hadizadeh-Talasaz, Fariba Mardani, Narjes Bahri, Hassan Rakhshandeh, Nasim Khajavian and Marzieh Taghieh
    Citation: BMC Complementary Medicine and Therapies 2022 22:226
  19. Complementary and alternative medicine (CAM) has played a critical role in ensuring universal access to basic health care services around the world. In Bangladesh, conventional medicine is a common approach fo...

    Authors: Md. Shahjalal, Jeff Gow, Md. Ashfikur Rahman, Md. Jakir Hossain, Md. Nafiul Alam Khan, Md. Sazzadul Alam, Ahmed Hossain and Rashidul Alam Mahumud
    Citation: BMC Complementary Medicine and Therapies 2022 22:225
  20. Oxidative stress can induce age-related diseases. Age-related retinal diseases, such as age-related macular degeneration (AMD), are difficult to cure owing to their complicated mechanisms. Although anti-neovas...

    Authors: Yibo Gong, Xuechun Wang, Yuchuan Wang, Peng Hao, Hao Wang, Yatu Guo and Wei Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:224
  21. Symphonia globulifera and Allophylus abyssinicus are used in the management of skin rashes and sores, cough, malaria, digestive diseases, stomach ache, wounds and helminthic infections among others in Uganda, Ken...

    Authors: Ben Lukubye, Clement Olusoji Ajayi, Rapheal Wangalwa and Grace Kagoro-Rugunda
    Citation: BMC Complementary Medicine and Therapies 2022 22:223
  22. Morinda citrifolia (Noni) is a plant that has long been used in various products such as foods and cosmetics. Although noni has been known to have immunostimulatory activity, detailed mechanism at the cellular le...

    Authors: Haeyeop Kim, Laily Rahmawati, Yo Han Hong, Su-Young Choi and Jae Youl Cho
    Citation: BMC Complementary Medicine and Therapies 2022 22:222
  23. The leaf of Eucalyptus globulus is commonly used in the traditional management of malaria. However, the efficacy of solvent fractions are didn’t study yet scientifically. Thus, this study aimed to investigate the...

    Authors: Mihret Ayalew, Seyfe Asrade Atnafie and Azmeraw Bekele
    Citation: BMC Complementary Medicine and Therapies 2022 22:221
  24. Zuojin formula, a traditional Chinese medicine, comprises Coptis chinensis and Evodia rutaecarpa. In our previous study, the total alkaloid extract from Zuojin formula (TAZF) showed potent and improved efficacy. ...

    Authors: Shuo Wang, Tao Zhang, Xiaoyan Liu, Zheng Yang, Ludi Li, Danping Shan, Yadong Gao, Yingzi Li, Yanying Li, Youbo Zhang and Qi Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:220
  25. Though there are reports about V. auriculifera antimicrobial activity, there is not enough information about its activity on some bacterial and fungal species. Besides, there was no quantitative evaluation done f...

    Authors: Teshale Etiso Wado, Sultan Suleman and Tesfaye Mohammed
    Citation: BMC Complementary Medicine and Therapies 2022 22:219
  26. Globally, the usage of herbal medicines (HMs) is increasingly growing in treating and preventing various ailments. Although, HMs play a vital role in healthcare, concerns have been raised over their safety. Si...

    Authors: Alemseghed Goitom, Feruz Yemane, Mussie Tsegay, Amanuel Kifleyesus, Senai Mihreteab Siele, Eyasu H. Tesfamariam and Nuru Abdu
    Citation: BMC Complementary Medicine and Therapies 2022 22:218
  27. Prasachandaeng (PSD) remedy has been empirically used in Thai traditional medicine to treat fever in bile duct and liver and cancer patients through Thai folk doctors. However, there have been no scientific re...

    Authors: Nuntika Prommee, Arunporn Itharat, Pakakrong Thongdeeying, Sunita Makchuchit, Weerachai Pipatrattanaseree, Adis Tasanarong, Buncha Ooraikul and Neal M. Davies
    Citation: BMC Complementary Medicine and Therapies 2022 22:217
  28. The traditional Chinese medicine (TCM) formula 01 for nasopharyngeal carcinoma (NPC01) is used in the management of head and neck cancers (HNCs), but whether NPC01 has an impact on the HR-QOL of patients with ...

    Authors: Li Yanwei, He Feng, Wang Xudong and Pan Zhanyu
    Citation: BMC Complementary Medicine and Therapies 2022 22:216
  29. Cordia myxa L. (Boraginaceae) is widely distributed in tropical regions and it’s fruits, leaves and stem bark have been utilized in folk medicine for treating trypanosomiasis caused by Trypanosoma cruzi. A popula...

    Authors: Gülsen Kendir, Ho Jung Bae, Jihyun Kim, Yongwoo Jeong, Hyo Jeoung Bae, Keontae Park, Xingquan Yang, Young-jin Cho, Ji-Young Kim, Seo Yun Jung, Ayşegül Köroğlu, Dae Sik Jang and Jong Hoon Ryu
    Citation: BMC Complementary Medicine and Therapies 2022 22:215
  30. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid glycoside, has various pharmacological effects on ...

    Authors: Ju-Young Kim, Yoon-Hee Cheon, Sung-Jun Ahn, Sung Chul Kwak, Chong Hyuk Chung, Chang Hoon Lee and Myeung Su Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:214
  31. Salvia-Nelumbinis naturalis (SNN), the extract of Chinese herbal medicine, has shown effects on NAFLD. This study aims to explore the underlying mechanism of SNN for regulating the lipid metabolism disorder in...

    Authors: Yang Liu, Yiping Li, Jue Wang, Lili Yang, Xiao Yu, Ping Huang, Haiyan Song and Peiyong Zheng
    Citation: BMC Complementary Medicine and Therapies 2022 22:213
  32. Complementary Medicine (CM) is widely used internationally but there is limited understanding of the forms of knowledge CM practitioners use in their clinical practice and how they use this knowledge in intera...

    Authors: Kate Davies, Milena Heinsch, Campbell Tickner, Caragh Brosnan, Amie Steel, Gupteswar Patel and Molly Marsh
    Citation: BMC Complementary Medicine and Therapies 2022 22:212
  33. Intestinal inflammation is considered to be an important characteristic of ulcerative colitis (UC) and the current medical treatments for UC are usually proposed to suppress abnormal intestinal immune response...

    Authors: Ming-Kuem Lin, Ya-Ting Yang, Li-Jen Lin, Wei-Hsuan Yu and Huan-Yuan Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:211
  34. Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the main cause of end-stage renal failure. Rhubarb is a widely used traditional Chinese herb, and it has exhibited efficacy in...

    Authors: Shaojie Fu, Yena Zhou, Cong Hu, Zhonggao Xu and Jie Hou
    Citation: BMC Complementary Medicine and Therapies 2022 22:210
  35. The Sheng-ji Hua-yu (SJHY) formula is a quite effective Traditional Chinese Medicines (TCM) in the treatment of delayed diabetic wounds. Previous research has shown that the SJHY formula has significant anti-i...

    Authors: Ning Xu, Yuanran Chen, Dongjie Guo, Yu Deng, Wanjun Guo, Xin Liu, Yi Wang, Hanzhi Lu, Aijun Liu, Jianyong Zhu and Fulun Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:209
  36. Acute pancreatitis is a common and potentially serious condition. However, a specific treatment for this condition is still lacking. Genistein, with its anti-oxidant and anti-inflammatory effects, could possib...

    Authors: Prasong Siriviriyakul, Jumlongluk Sriko, Kanjana Somanawat, Maneerat Chayanupatkul, Naruemon Klaikeaw and Duangporn Werawatganon
    Citation: BMC Complementary Medicine and Therapies 2022 22:208
  37. The number of COVID-19 cases continues to grow in Indonesia. This phenomenon motivates researchers to find alternative drugs that function for prevention or treatment. Due to the rich biodiversity of Indonesia...

    Authors: Linda Erlina, Rafika Indah Paramita, Wisnu Ananta Kusuma, Fadilah Fadilah, Aryo Tedjo, Irandi Putra Pratomo, Nabila Sekar Ramadhanti, Ahmad Kamal Nasution, Fadhlal Khaliq Surado, Aries Fitriawan, Khaerunissa Anbar Istiadi and Arry Yanuar
    Citation: BMC Complementary Medicine and Therapies 2022 22:207
  38. Ginkgo biloba extracts (GBE) have been used in traditional medicines for centuries. GBE has been shown to deliver protective effects against symptoms of age-related cognitive decline. Despite there being standard...

    Authors: David Briskey and Amanda Rao
    Citation: BMC Complementary Medicine and Therapies 2022 22:206
  39. In recent decades, it has been possible to observe an increase in Complementary and Alternative Medicine (CAM) usage globally for both disease prevention and health promotion purposes. we aim to estimate the p...

    Authors: Patricia de Moraes Mello Boccolini, Karine de Lima Sírio Boclin, Islândia Maria Carvalho de Sousa and Cristiano Siqueira Boccolini
    Citation: BMC Complementary Medicine and Therapies 2022 22:205
  40. Existing evidence marked a prevalent use of Complementary and Alternative Medicine (CAM) therapies in Lebanon that is concomitant with low rates of disclosure to health care providers and limited knowledge amo...

    Authors: Zeinab Jaafar, Jennifer Ayoub, Rena Hamadeh, Samar Baydoun, Gladys Honein-AbouHaidar, Jinan Banna, Mohamad Alameddine and Farah Naja
    Citation: BMC Complementary Medicine and Therapies 2022 22:204
  41. Henna (Lawsonia inermis) with anti-bacterial properties has been widely used in traditional medicine especially Persian medicine. Henna oil is suggested for diseases of infectious origin, such as cervical ulcers....

    Authors: M. Fatahi Bafghi, S. Salary, F. Mirzaei, H. Mahmoodian, H. Meftahizade and R. Zareshahi
    Citation: BMC Complementary Medicine and Therapies 2022 22:203
  42. Research exploring the use of specific Complementary and Alternative Medicine (CAM) modalities by Norwegian cancer patients is sparse. The aims of this study were therefor to map the different CAM modalities c...

    Authors: Agnete E. Kristoffersen, Jorunn V. Nilsen, Trine Stub, Johanna Hök Nordberg, Barbara Wider, Dana Mora, Kiwumulo Nakandi and Mona Bjelland
    Citation: BMC Complementary Medicine and Therapies 2022 22:202
  43. The aim of this study was to evaluate the biological effects of hydroalcoholic extract of Psidium guajava L leaves and phenytoin as a standard agent on the induced oral mucosal wound.

    Authors: Faezeh Ghaderi, Elham Ebrahimi, Fatemeh Sari Aslani, Omid Koohi-Hosseinabadi, Farhad Koohpeyma, Cambyz Irajie, Nader Tanideh and Aida Iraji
    Citation: BMC Complementary Medicine and Therapies 2022 22:201
  44. Determining which therapies fall under the umbrella of complementary, alternative, and/or integrative medicine (CAIM) is difficult for several reasons. An operational definition is dynamic, and changes dependi...

    Authors: Jeremy Y. Ng, Tushar Dhawan, Ekaterina Dogadova, Zhala Taghi-Zada, Alexandra Vacca, Renee-Gabrielle Fajardo, Hooriya A. Masood, Riva Patel, Samira Sunderji, L. Susan Wieland and David Moher
    Citation: BMC Complementary Medicine and Therapies 2022 22:200
  45. The incidence of allergic reaction is increasing year by year, but the specific mechanism is still unclear. Paeonia lactiflora Pall.(PLP) is a traditional Chinese medicine with various pharmacological effects suc...

    Authors: Yang Zhao, Hui Li, Xiangsheng Li, Yizhao Sun, Yuxin Shao, Yanfen Zhang and Zhongcheng Liu
    Citation: BMC Complementary Medicine and Therapies 2022 22:199
  46. Berberine (BBR) has been found to have antiobesity effects, and obesity can lead to adipose tissue degeneration. As a special adipose tissue, perivascular adipose tissue (PVAT) is closely related to vascular f...

    Authors: Man Wang, Xufang Geng, Kaipeng Li, Yawen Wang, Xiaofeng Duan, Congcong Hou, Lili Zhao, Huimin Zhou and Ding Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:198
  47. Plantainoside D is widely existed in the herbs and possesses various pharmacological activities, making it possible to co-administrate with other herbs. Its effect on cytochrome P450 enzymes (P450) is a risk f...

    Authors: Jin Zhou, Xian Qian, Yanqing Zhou, Shili Xiong, Shuxia Ji, Ying Wang and Ping Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:197
  48. Ulcerative colitis (UC) is an inflammatory bowel disease. Fucoidan, sulfated polysaccharide of brown seaweed, demonstrates various pharmacological actions as anti-inflammatory, anti-tumor and anti-bacterial ef...

    Authors: Alaa Bagalagel, Reem Diri, Ahmad Noor, Deina Almasri, Hussain T. Bakhsh, Hussam I. Kutbi and Mohammed M. H. Al-Gayyar
    Citation: BMC Complementary Medicine and Therapies 2022 22:196
  49. The rise of multidrug-resistant (MDR) bacteria is a real public health problem worldwide and is responsible for the increase in hospital infections. Donella welwitschii is a liana or shrub belonging to the family...

    Authors: Michel-Gael F. Guefack, Marcelle O. Ngangoue, Armelle T. Mbaveng, Paul Nayim, Jenifer R. N. Kuete, Carine M. N. Ngaffo, Godloves F. Chi, Bathelemy Ngameni, Bonaventure T. Ngadjui and Victor Kuete
    Citation: BMC Complementary Medicine and Therapies 2022 22:194