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  1. Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growi...

    Authors: Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew, Zhi-Yu Qiu, Xin-Rong Cheryl Tsai, Sin-Yi How, Keng-Yan Caleb Yip, Chay-Hoon Tan and Hwee-Ling Koh

    Citation: BMC Complementary Medicine and Therapies 2020 20:91

    Content type: Research article

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  2. Parents often choose Complementary and Alternative Medicine (CAM) as a supportive agent with the aim to reduce cancer treatment-related symptoms in their children. Therefore, it is necessary to understand pare...

    Authors: Trine Stub, Agnete E. Kristoffersen, Grete Overvåg and Miek C. Jong

    Citation: BMC Complementary Medicine and Therapies 2020 20:90

    Content type: Research article

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  3. Hydrolates, complex mixtures containing traces of essential oils (EOs), are inexpensive, easy to make and less toxic than their corresponding EOs. The antibacterial and antifungal activity of the hydrolate of Cor...

    Authors: Andreana Marino, Antonia Nostro, Narcisa Mandras, Janira Roana, Giovanna Ginestra, Natalizia Miceli, Maria Fernanda Taviano, Fabrizio Gelmini, Giangiacomo Beretta and Vivian Tullio

    Citation: BMC Complementary Medicine and Therapies 2020 20:89

    Content type: Research article

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  4. Sedum sarmentosum is traditionally used to treat various inflammatory diseases in China. It has protective effects against acute liver injury, but the exact mechanism of such effects remains unclear. This study i...

    Authors: Li Hao, Ming-wei Liu, Song-tao Gu, Xue Huang, Hong Deng and Xu Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:88

    Content type: Research article

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  5. The antiprotozoal and antioxidant activities of Viola tricolor and Laurus nobilis have been reported recently. Thus, the existing study pursued to assess the growth inhibition effect of methanolic extract of V. t...

    Authors: Gaber El-Saber Batiha, Amany Magdy Beshbishy, Luay Alkazmi, Oluyomi Stephen Adeyemi, Eman Nadwa, Eman Rashwan, Amany El-Mleeh and Ikuo Igarashi

    Citation: BMC Complementary Medicine and Therapies 2020 20:87

    Content type: Research article

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  6. Myrtus communis is a typical plant of Mediterranean area. The different parts of this plant such as berries, branches, and leaves have been used worldwide as a traditional/folk medicine for the treatment of vario...

    Authors: Mushtaq A. Mir, Nasreena Bashir, Abdulkhaleg Alfaify and Mohammed D. Y. Oteef

    Citation: BMC Complementary Medicine and Therapies 2020 20:86

    Content type: Research article

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  7. Honey is a versatile and complex substance consisting of bioactive chemicals which vary according to many bee and environmental factors. The aim of this study was to assess the physical and antimicrobial prope...

    Authors: Elijah Brown, Michel O’Brien, Karla Georges and Sharianne Suepaul

    Citation: BMC Complementary Medicine and Therapies 2020 20:85

    Content type: Research article

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  8. Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are u...

    Authors: Mitsuki Tabata, Masanobu Tsubaki, Tomoya Takeda, Keisuke Tateishi, Katsumasa Tsurushima, Motohiro Imano, Takao Satou, Toshihiko Ishizaka and Shozo Nishida

    Citation: BMC Complementary Medicine and Therapies 2020 20:84

    Content type: Research article

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  9. Recent studies pointed up that curcumin produces an anti-nociceptive effect in inflammatory and neuropathic pain. However, the possible mechanisms of action that underline the anti-allodynic effect induced by ...

    Authors: Tracy Pastrana-Quintos, Giovanna Salgado-Moreno, Julia Pérez-Ramos, Arrigo Coen and Beatriz Godínez-Chaparro

    Citation: BMC Complementary Medicine and Therapies 2020 20:83

    Content type: Research article

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  10. Daily “eye exercises,” massaging of periocular acupuncture pressure points, have been part of China’s national vision care policy in schools for some 50 years. However, the effect of eye exercises on myopia pr...

    Authors: Huan Wang, Yiwei Qian, Nathan Congdon, Matthew Boswell, Scott Rozelle and Xiaochen Ma

    Citation: BMC Complementary Medicine and Therapies 2020 20:82

    Content type: Research article

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  11. Skin-related diseases affect every individual irrespective of age, gender or social status. Since time immemorial, humans have explored natural resources from their environment for the maintenance of the skin....

    Authors: Mamokete Venolia Setshego, Adeyemi Oladapo Aremu, Obakeng Mooki and Wilfred Otang-Mbeng

    Citation: BMC Complementary Medicine and Therapies 2020 20:81

    Content type: Research article

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  12. The health benefits of botanicals is linked to their phytochemicals that often exert pleiotropic effects via targeting multiple molecular signaling pathways such as the peroxisome proliferator-activated recept...

    Authors: Mebrahtom Gebrelibanos Hiben, Laura de Haan, Bert Spenkelink, Sebastiaan Wesseling, Jacques Vervoort and Ivonne M. C. M. Rietjens

    Citation: BMC Complementary Medicine and Therapies 2020 20:80

    Content type: Research article

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  13. In the context of searching for potent, safe, natural antimicrobial agents to combate the global antimicrobial resistance (AMR) phenomenon, the current study evaluates for the first time ever, the broad-spectr...

    Authors: Huda Naeim, Amr El-Hawiet, Raoufa A. Abdel Rahman, Ahmed Hussein, Maha A. El Demellawy and Amira M. Embaby

    Citation: BMC Complementary Medicine and Therapies 2020 20:79

    Content type: Research article

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  14. The active components of Dracocephalum moldavica L. (TFDM) can inhibit myocardial ischemia by inhibiting oxidative stress. However, the effects of TFDM on astrocytes have not been investigated in vitro. The curre...

    Authors: Rui-Fang Zheng, Yan-Wen Du, Cheng Zeng, Hui-Fang Wang, Jian-Guo Xing and Ming Xu

    Citation: BMC Complementary Medicine and Therapies 2020 20:78

    Content type: Research article

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  15. Germacrone is an anti-inflammatory ingredient in the Chinese medicine zedoary turmeric. The purpose of this study was to explore the protective mechanism of germacrone against PC12 cells injury caused by oxyge...

    Authors: Jianxing Zhang, Li Yuan, Sujie Wang, Jiang Liu, Huiqin Bi, Guojuan Chen, Jingjing Li and Lili Chen

    Citation: BMC Complementary Medicine and Therapies 2020 20:77

    Content type: Research article

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  16. The embryos of Nelumbo nucifera Gaertn seeds, lianzixin, are used in China as food and traditional herbal medicine. Principal therapeutic indications are insomnia, anxiety and pyrexia. Caffeine is a psychostimula...

    Authors: Jingjing Chen, Mimi Tang, Manhua Liu, Yueping Jiang, Bin Liu and Shao Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:76

    Content type: Research article

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  17. Various extracts of Hovenia dulcis have been commonly used in Asia for cases of alcohol-related disorders. Fermentation is reported to enhance the level and biological activities of various bio-constituents of pl...

    Authors: Na-Hye Park, Seung-Jin Lee, Abraham Fikru Mechesso, Naila Boby, Quah Yixian, Woong-Kyu Yoon, Sam-Pin Lee, Jong-Suk Lee and Seung-Chun Park

    Citation: BMC Complementary Medicine and Therapies 2020 20:75

    Content type: Research article

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  18. This study investigated the anticancer potential of the medicinal herb, Cleome droserifolia (CD), a local plant of the Arabian Peninsula. C. droserifolia is traditionally known for its rubefacient, anti-diabetic,...

    Authors: Neena Gopinathan Panicker, Sameera Omar Mohammed Saeed Balhamar, Shaima Akhlaq, Mohammed Mansoor Qureshi, Najeeb Ur Rehman, Ahmed Al-Harrasi, Javid Hussain and Farah Mustafa

    Citation: BMC Complementary Medicine and Therapies 2020 20:74

    Content type: Research article

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  19. Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, a...

    Authors: Mustafa T. Ardah, Simona S. Ghanem, Sara A. Abdulla, Guohua Lv, Mohamed M. Emara, Katerina E. Paleologou, Nishant N. Vaikath, Jia-Hong Lu, Min Li, Konstantinos Vekrellis, David Eliezer and Omar M. A. El-Agnaf

    Citation: BMC Complementary Medicine and Therapies 2020 20:73

    Content type: Research article

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  20. Flavonoids from plant medicines are supposed to be viable alternatives for the treatment of type 2 diabetes (T2D) as less toxicity and side effects. Radix scutellariae (RS) is a widely used traditional medicine i...

    Authors: Le Wang, Nana Tan, Huan Wang, Jingbo Hu, Wenbo Diwu and Xiaoling Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:72

    Content type: Research article

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  21. Cranberry has been studied as a potential anticancer agent as it is capable of inducing apoptosis within cancer cells. The aim of this study was to better define the mechanism by which cranberry triggers apopt...

    Authors: Rasha A. Mansouri and Susan S. Percival

    Citation: BMC Complementary Medicine and Therapies 2020 20:71

    Content type: Research article

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  22. Post-traumatic stress disorder (PTSD) is an extreme mood disorder that occurs after experiencing extreme stress, and patients with this disorder are known to accompany with symptoms of depression, anxiety, and...

    Authors: Bombi Lee, Gwang Muk Choi and Bongjun Sur

    Citation: BMC Complementary Medicine and Therapies 2020 20:70

    Content type: Research article

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  23. Human Immunodeficiency Virus (HIV) persists to be a significant public health issue worldwide. The current strategy for the treatment of HIV infection, Highly Active Antiretroviral Therapy (HAART), has reduced...

    Authors: Aparna Palshetkar, Navin Pathare, Nutan Jadhav, Megha Pawar, Ashish Wadhwani, Smita Kulkarni and Kamalinder K. Singh

    Citation: BMC Complementary Medicine and Therapies 2020 20:69

    Content type: Research article

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  24. Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and has also been associated with a high degree of malignancy and enhanced metastatic capacity. Curcumin (CUR) is well k...

    Authors: Cheng Huang, Hsu-Feng Lu, Yu-Hsuan Chen, Jui-Chieh Chen, Wen-Hsiang Chou and Hsiu-Chen Huang

    Citation: BMC Complementary Medicine and Therapies 2020 20:68

    Content type: Research article

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  25. Aspergillus fumigatus, an opportunistic fungal pathogen is associated with a wide array of diseases. It produces 1, 8-dihydroxy naphthalene (DHN) melanin that imparts greenish grey color to conidia and is an impo...

    Authors: Shanu Hoda, Maansi Vermani, Rajesh K. Joshi, Jata Shankar and Pooja Vijayaraghavan

    Citation: BMC Complementary Medicine and Therapies 2020 20:67

    Content type: Research article

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  26. Danhong injection (DHI), which is one of the most well-known Traditional Chinese Medicine (TCM) injections, widely used to treat unstable angina (UA). However, its underlying pharmacological mechanisms need to...

    Authors: Siyu Guo, Jiarui Wu, Wei Zhou, Xinkui Liu, Jingyuan Zhang, Shanshan Jia, Ziqi Meng, Shuyu Liu, Mengwei Ni and Yingying Liu

    Citation: BMC Complementary Medicine and Therapies 2020 20:66

    Content type: Research article

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  27. Diabetes mellitus (DM) is a major public health problem and one of the most challenging diseases worldwide. According to the World Health Organization (WHO), the Kingdom of Saudi Arabia (KSA) has the second hi...

    Authors: Aljawharah Alqathama, Ghadeer Alluhiabi, Halah Baghdadi, Lujain Aljahani, Ola Khan, Sara Jabal, Shorooq Makkawi and Farah Alhomoud

    Citation: BMC Complementary Medicine and Therapies 2020 20:65

    Content type: Research article

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  28. The pressed juice of Barley Grass (BG) has become very popular among people for various assumed benefits along with many testimonies of people who have been healed from various ailments such as anemia, cancer,...

    Authors: Mamata Panthi, Romit Kumar Subba, Bechan Raut, Dharma Prasad Khanal and Niranjan Koirala

    Citation: BMC Complementary Medicine and Therapies 2020 20:64

    Content type: Research article

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  29. Giardia duodenalis causes giardiasis in humans, particularly in developing countries. Despite the availability of treatments, resistance to some of the commercial anti-Giardia drugs has been reported in addition ...

    Authors: Ai-rada Pintong, Jiraporn Ruangsittichai, Sumate Ampawong, Kanthinich Thima, Patchara Sriwichai, Narumon Komalamisra and Supaluk Popruk

    Citation: BMC Complementary Medicine and Therapies 2020 20:63

    Content type: Research article

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  30. Natural products constitute a promising class of therapeutics for the treatment of gingivitis and periodontitis as well as the maintenance of oral health. However, the limited understanding behind their potent...

    Authors: Ana M. Chang, Shatha Bamashmous, Richard P. Darveau and Sunethra Rajapakse

    Citation: BMC Complementary Medicine and Therapies 2020 20:62

    Content type: Research article

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  31. Pharmacokinetic interaction is one of the most important indices for the evaluation of the compatibility of herbal medicines. Both Gancao (Glycyrrhizae Radix et Rhizoma) and Huanglian (Coptidis Rhizoma) are commo...

    Authors: Ji-Quan Zhang, Rui Wang, Ting Zhou, Qing Zhao, Chun-Cao Zhao and Bing-Liang Ma

    Citation: BMC Complementary Medicine and Therapies 2020 20:61

    Content type: Research article

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  32. Traditional medicine serves as a form of primary health care for more than 80% of African populations. Currently, there is no research documenting if and how African migrant communities engage with their tradi...

    Authors: Zewdneh Shewamene, Tinashe Dune and Caroline A. Smith

    Citation: BMC Complementary Medicine and Therapies 2020 20:60

    Content type: Research article

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  33. Naturopathy is a distinct system of traditional and complementary medicine recognized by the World Health Organization and defined by its philosophic approach to patient care, rather than the treatments used b...

    Authors: Amie Steel, Hope Foley, Ryan Bradley, Claudine Van De Venter, Iva Lloyd, Janet Schloss, Jon Wardle and Rebecca Reid

    Citation: BMC Complementary Medicine and Therapies 2020 20:59

    Content type: Research article

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  34. In response to high demand and the growing body of evidence for traditional and complementary therapies, the practice of integrative medicine and integrative healthcare has emerged where these therapies are bl...

    Authors: Carolyn Ee, Kate Templeman, Suzanne Grant, Nicole Avard, Michael de Manincor and Jennifer Hunter

    Citation: BMC Complementary Medicine and Therapies 2020 20:58

    Content type: Research article

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  35. The well-known traditional Chinese herbal formula Guizhi Fuling Wan (GFW) was recently reported to improve the curative effects of chemotherapy for ovarian cancer with few clinical side effects. The present st...

    Authors: Li Han, Xueyun Cao, Zhong Chen, Xiaojuan Guo, Lei Yang, Yubing Zhou and Hua Bian

    Citation: BMC Complementary Medicine and Therapies 2020 20:57

    Content type: Research article

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  36. Ficus deltoidea (FD) has been shown to have antidiabetic, anti-inflammatory, antinociceptive and antioxidant properties. However, its effects on key events in the pathogenesis of atherosclerosis are unknown.

    Authors: Amirah Mohd Ariff, Nurul Ain Abu Bakar, Suhaila Abd. Muid, Effat Omar, Nor Hadiani Ismail, Abdul Manaf Ali, Noor Alicezah Mohd Kasim and Hapizah Mohd Nawawi

    Citation: BMC Complementary Medicine and Therapies 2020 20:56

    Content type: Research article

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  37. Canarium patentinervium leaves are used by the local indigenous people of Malaysia for wound healing. The current study is undertaken to screen the comprehensive antibacterial activity of the leaves and barks ext...

    Authors: R. Mogana, A. Adhikari, M. N. Tzar, R. Ramliza and C. Wiart

    Citation: BMC Complementary Medicine and Therapies 2020 20:55

    Content type: Research article

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  38. Oxidative stress mediates the nerve injury during the pathogenesis of Alzheimer’s disease (AD). Protecting against oxidative stress damage is an important strategy to prevent and treat AD. Di-Huang-Yi-Zhi (DHY...

    Authors: Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu and Hong-Mei An

    Citation: BMC Complementary Medicine and Therapies 2020 20:54

    Content type: Research article

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  39. The aim of the randomized double-blinded clinical trial was to evaluate the effect of tooth brushing with Salvadora persica (miswak) sticks on Streptococcus mutans count and the mean plaque score relative to brus...

    Authors: Heba J. Sabbagh, Khalil S. AlGhamdi, Hattan T. Mujalled and Sara M. Bagher

    Citation: BMC Complementary Medicine and Therapies 2020 20:53

    Content type: Research article

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  40. This study seeks to investigate factors associated with using complementary and alternative medicine (CAM) for a mental illness among the three major ethnic groups (Chinese, Indians and Malays) in the general ...

    Authors: Vanessa Seet, Edimansyah Abdin, Janhavi A. Vaingankar, Shazana Shahwan, Sherilyn Chang, Bernard Lee, Siow Ann Chong and Mythily Subramaniam

    Citation: BMC Complementary Medicine and Therapies 2020 20:52

    Content type: Research article

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  41. The use of medicinal plants or other alternative practices can be the only therapeutic resources for many communities and ethnic groups, especially in developing countries. In Brazil, the Ministry of Health in...

    Authors: Patricia de Moraes Mello Boccolini and Cristiano Siqueira Boccolini

    Citation: BMC Complementary Medicine and Therapies 2020 20:51

    Content type: Research article

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  42. Globally, more than 170 million people are infected with hepatitis C virus, a major cause of cirrhosis and hepatocellular carcinoma. The Yinchenhao Decoction (YCHD) is a classic formula comprising three herbal...

    Authors: Jingyuan Zhang, Xinkui Liu, Jiarui Wu, Wei Zhou, Jinhui Tian, Siyu Guo, Shan Shan Jia, Ziqi Meng and Mengwei Ni

    Citation: BMC Complementary Medicine and Therapies 2020 20:50

    Content type: Research article

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  43. Inflammation is one of the key components in the initiation and progression of hepatic diseases. If not treated, inflammation may cause cell dysplasia, and ultimately cancer. In the current study, we investiga...

    Authors: Adeeb Shehzad, Shagufta Rehmat, Salman Ul-Islam, Rizwan Ahmad, Meneerah Aljafary, Noor A. Alrushaid and Ebtesam A. Al-Suhaimi

    Citation: BMC Complementary Medicine and Therapies 2020 20:49

    Content type: Research article

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  44. Radix isatidis has been used in China and other Asian countries for its antiviral and anti-inflammatory effects for thousands of years. However, the antiviral effect of Radix isatidis polysaccharide against pseud...

    Authors: Chao Tong, Zewen Chen, Fang Liu, Yanyan Qiao, Tong Chen and Xuebing Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:48

    Content type: Research article

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  45. Cyanidin-3-glucoside (C3G), a major anthocyanin present in berries, exhibits a strong antioxidant and has been shown to possess a neuroprotection. Prolonged exposure to glutamate will lead to oxidative damage ...

    Authors: Monruedee Sukprasansap, Pithi Chanvorachote and Tewin Tencomnao

    Citation: BMC Complementary Medicine and Therapies 2020 20:46

    Content type: Research article

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  46. Dental caries is one of the most prevalent chronic oral diseases worldwide. Dental caries is mainly associated with Streptococcus mutans and the Lactobacillus species. A specific relationship was found between ni...

    Authors: Abdulaziz M. Alshahrani and Richard L. Gregory

    Citation: BMC Complementary Medicine and Therapies 2020 20:45

    Content type: Research article

    Published on:

  47. The effect of ginsenosides on the growth and apoptosis of human lens epithelial (HLE) B3 cells exposed to H2O2 was investigated. In addition, the effect of ginsenosides on gene expression in HLE-B3 cells was anal...

    Authors: Zhewen Wang, Shiping Zhou, Xiaoqing Hu and Jiannan Chai

    Citation: BMC Complementary Medicine and Therapies 2020 20:44

    Content type: Research article

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  48. Despite the large number of trials conducted using herbal oral care products for the reduction of dental plaque or gingivitis, results are conflicting and inconclusive.

    Authors: Chandrashekar Janakiram, Ramanarayanan Venkitachalam, Paul Fontelo, Timothy J. Iafolla and Bruce A. Dye

    Citation: BMC Complementary Medicine and Therapies 2020 20:43

    Content type: Research article

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  49. Qilin pills (QLPs), a classic Traditional Chinese Medicine (TCM) formula for treating male infertility, effectively improve semen quality in clinical trials. This study was designed to evaluate the effects of ...

    Authors: Kaishu Zhang, Longlong Fu, Qi An, Weihong Hu, Jianxin Liu, Xiuming Tang, Yu Ding, Wenhong Lu, Xiaowei Liang, Xuejun Shang and Yiqun Gu

    Citation: BMC Complementary Medicine and Therapies 2020 20:42

    Content type: Research article

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  50. Most randomized controlled trials (RCTs) of traditional medicine (such as traditional Chinese medicine (TCM), psychotherapy or behavioral therapy, and dietary interventions, etc.) have reported that they could...

    Authors: Qiliang Chen, Qiong Wang, Shanshan Ding, Shunan Li, Yuanyuan Zhang, Shujiao Chen, Xuejuan Lin, Candong Li and Tetsuya Asakawa

    Citation: BMC Complementary Medicine and Therapies 2020 20:41

    Content type: Research article

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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