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  1. Evidence showed that Tai Chi may have beneficial effects among hypertensive individuals, although the results are not convincing. We aim to conduct a high-quality clinical trial with 24-h BP measurement to pro...

    Authors: Yuxi Li, Dongling Zhong, Chao Dong, Lihong Shi, Yaling Zheng, Yongguo Liu, Qiaoqin Li, Hui Zheng, Juan Li, Tianyu Liu and Rongjiang Jin

    Citation: BMC Complementary Medicine and Therapies 2021 21:23

    Content type: Study protocol

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  2. Cancer is a multifactorial disease caused by uncontrolled proliferation of cells. About 50–80% of cancer patients develop cachexia, a complex metabolic syndrome associated with an increase of mortality and mor...

    Authors: Henrique Jorge Novaes Morgan, Aislan Quintiliano Delgado, Luiz Leonardo Saldanha, Nathalia Aparecida De Paula Camaforte, Anne Lígia Dokkedal and José Roberto Bosqueiro

    Citation: BMC Complementary Medicine and Therapies 2021 21:20

    Content type: Research article

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  3. During the last few decades, patients worldwide have been interested in using alternative medicine in treating diseases to avoid the increased side effects of chemical medications. Green coffee is unroasted co...

    Authors: Haddad A. El Rabey, Samar M. Rezk, Mohamed I. Sakran, Ghena M. Mohammed, Omar Bahattab, Maha J. Balgoon, Mohamed A. Elbakry and Nadia Bakry

    Citation: BMC Complementary Medicine and Therapies 2021 21:19

    Content type: Research article

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  4. Norwogonin is a natural flavone with three phenolic hydroxyl groups in skeletal structure and has excellent antioxidant activity. However, the neuroprotective effect of norwogonin remains unclear. Here, we inv...

    Authors: Linlin Jing, Rongmin Gao, Jie Zhang, Dongmei Zhang, Jin Shao, Zhengping Jia and Huiping Ma

    Citation: BMC Complementary Medicine and Therapies 2021 21:18

    Content type: Research article

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  5. About 70% of Ghanaians depend on traditional, complementary and integrative medicine (TCIM) practices for primary healthcare needs. It was therefore integrated into mainstream healthcare delivery system by the...

    Authors: Angela Kenu, Ernest Kenu, Delia Akosua Bandoh and Moses Aikins

    Citation: BMC Complementary Medicine and Therapies 2021 21:14

    Content type: Research article

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  6. Alcohol abuse is a major problem worldwide and it affects people’s health and economy. There is a relapse in alcohol intake due to alcohol withdrawal. Alcohol withdrawal anxiety-like behavior is a symptom that...

    Authors: Lalit Sharma, Aditi Sharma, Ashutosh Kumar Dash, Gopal Singh Bisht and Girdhari Lal Gupta

    Citation: BMC Complementary Medicine and Therapies 2021 21:13

    Content type: Research article

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  7. Activation of renal fibroblasts is a critical mechanism in the process of renal fibrosis. As a commonly used herbal formula, Shenkang (SK) has been found to attenuate renal fibrosis and renal parenchyma destru...

    Authors: Tianyu Qin, You Wu, Tonghua Liu and Lili Wu

    Citation: BMC Complementary Medicine and Therapies 2021 21:12

    Content type: Research article

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  8. The traditional Chinese medicine formula Si-Jun-Zi-Tang (SJZT) has a long history of application in the treatment of functional dyspepsia (non-ulcer dyspepsia, FD)-like symptoms. SJZT-based therapies have been cl...

    Authors: Yaping Wang, Bin Liu, Xiuqiong Fu, Tiejun Tong and Zhiling Yu

    Citation: BMC Complementary Medicine and Therapies 2021 21:11

    Content type: Research article

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  9. Curcumin has been demonstrated to exert anti-oxidant, anti-fibrotic, anti-inflammatory, and anti-cancer activities. This study was conducted to observe the effect and inner mechanism of curcumin in rats with r...

    Authors: Wei Li, Liangjun Jiang, Xianzhou Lu, Xianrong Liu and Mingjiong Ling

    Citation: BMC Complementary Medicine and Therapies 2021 21:10

    Content type: Research article

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  10. Epilepsy, one of the most common neurological disorders, affects over 70 million people worldwide. Rhynchophylline displays a wide variety of pharmacologic actives. However, the pharmacologic effects of rhynch...

    Authors: Hua Geng, Xuqin Chen and Chengzhong Wang

    Citation: BMC Complementary Medicine and Therapies 2021 21:9

    Content type: Research article

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  11. The benefits of qigong for systolic and diastolic blood pressure (BP) reduction have been noted in previously published systematic reviews; however, the data on its effectiveness has been at best scarce. We ai...

    Authors: Siew Mooi Ching, Naidu Ragubathi Mokshashri, Maharajan Mari Kannan, Kai Wei Lee, Nurin Amalina Sallahuddin, Jun Xun Ng, Jie Lin Wong, Navin Kumar Devaraj, Fan Kee Hoo, Yee Shen Loo and Sajesh K. Veettil

    Citation: BMC Complementary Medicine and Therapies 2021 21:8

    Content type: Research article

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  12. Stroke causes lasting brain damage that has numerous impacts on the survivor’s physical, psychosocial, and spiritual well-being. Young survivors (< 65 years old) tend to suffer more because of their longer ove...

    Authors: Caitlin Kar Pui Chan, Temmy Lee Ting Lo, Adrian Ho Yin Wan, Pamela Pui Yu Leung, Marco Yiu Chung Pang and Rainbow Tin Hung Ho

    Citation: BMC Complementary Medicine and Therapies 2021 21:7

    Content type: Study protocol

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  13. Germacrone (GM) is a terpenoid compound which is reported to have anti-inflammatory and anti-oxidative effects. However, its role in treating traumatic brain injury (TBI) remains largely unknown.

    Authors: Sujing Zhuang, Baogui Liu, Shifeng Guo, Yanzhong Xue, Lin Wu, Shiqi Liu, Chunling Zhang and Xiuyan Ni

    Citation: BMC Complementary Medicine and Therapies 2021 21:6

    Content type: Research article

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  14. Correspondence from Yu et al. identify methodological issues with the systematic review of manual therapy for pediatric manuscript. Like any research study, limitations are important for readers to keep in con...

    Authors: Katherine A. Pohlman, Kristian Anderson, Beth Carleo and Brian Gleberzon

    Citation: BMC Complementary Medicine and Therapies 2021 21:5

    Content type: Correspondence

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    The original article was published in BMC Complementary Medicine and Therapies 2021 21:4

  15. Prevost et al. published a systematic review evaluating the use of manual therapy for clinical conditions in the pediatric population in 2019. However, several methodological flaws in the conduct of the review...

    Authors: Hainan Yu, Heather Shearer, Anne Taylor-Vaisey, Silvano Mior, Leslie Verville, Gaelan Connell and Pierre Côté

    Citation: BMC Complementary Medicine and Therapies 2021 21:4

    Content type: Correspondence

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    The Correspondence to this article has been published in BMC Complementary Medicine and Therapies 2021 21:5

  16. Generally, complementary and alternative therapies (CAT) are accepted methods of treatment by patients with various types of conditions. Their use is becoming especially prevalent among patients with eye probl...

    Authors: Dania Jaber, Rafat Abu Ghannam, Waleed Rashed, Mohammad Shehadeh and Sa’ed H. Zyoud

    Citation: BMC Complementary Medicine and Therapies 2021 21:3

    Content type: Research article

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  17. Patients with lymphoedema are at high risk of getting bacterial and fungal wound infections leading to acute inflammatory episodes associated with cellulitis and erysipelas. In Ethiopia, wound infections are t...

    Authors: Dereje Nigussie, Gail Davey, Belete Adefris Legesse, Abebaw Fekadu and Eyasu Makonnen

    Citation: BMC Complementary Medicine and Therapies 2021 21:2

    Content type: Research article

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  18. Hypercholesterolemia has posed a serious threat of heart diseases and stroke worldwide. Xanthine oxidase (XO), the rate-limiting enzyme in uric acid biosynthesis, is regarded as the root of reactive oxygen spe...

    Authors: Rishab Marahatha, Saroj Basnet, Bibek Raj Bhattarai, Prakriti Budhathoki, Babita Aryal, Bikash Adhikari, Ganesh Lamichhane, Darbin Kumar Poudel and Niranjan Parajuli

    Citation: BMC Complementary Medicine and Therapies 2021 21:1

    Content type: Research article

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  19. Rhinoviruses and influenza viruses cause millions of acute respiratory infections annually. Symptoms of mild acute respiratory infections are commonly treated with over-the-counter products like ambroxol, brom...

    Authors: Christin Walther, Kristin Döring and Michaela Schmidtke

    Citation: BMC Complementary Medicine and Therapies 2020 20:380

    Content type: Research article

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  20. Aloe’s reported bioactivities (anticancer, anti-inflammatory and wound healing) suggest they might inhibit a subgroup of matrix metalloproteinases (MMPs) called gelatinases (MMP-2 and MMP-9). The goal of the pres...

    Authors: Ana Lima, Paula Batista-Santos, Eduarda Veríssimo, Patrícia Rebelo and Ricardo Boavida Ferreira

    Citation: BMC Complementary Medicine and Therapies 2020 20:379

    Content type: Research article

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  21. Diabetic cardiomyopathy is a main cause of the increased morbidity in diabetic patients, no effective treatment is available so far. Polydatin, a resveratrol glucoside isolated from the Polygonum cuspidatum, was ...

    Authors: Ying-Ying Tan, Lei-Xin Chen, Ling Fang and Qi Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:378

    Content type: Research article

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  22. Previous studies have found that Hugan Qingzhi tablet (HQT) has significant lipid-lowering and antioxidant effects on non-alcoholic fatty liver disease (NAFLD). Moreover, the results of proteomic analysis conf...

    Authors: Miaoting Yang, Zhijuan Chen, Shijian Xiang, Fan Xia, Waijiao Tang, Xiaorui Yao and Benjie Zhou

    Citation: BMC Complementary Medicine and Therapies 2020 20:377

    Content type: Research article

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  23. Obesity and its associated diseases have become a major world-wide health problem. Purple-leaf Tea (Camellia sinensis L.) (PLT), that is rich of anthocyanins, has been shown to have preventive effects on obesity ...

    Authors: Yu-Chun Lin, Hsu-Feng Lu, Jui-Chieh Chen, Hsiu-Chen Huang, Yu-Hsin Chen, Yen-Shuo Su, Chien-Yi Tung and Cheng Huang

    Citation: BMC Complementary Medicine and Therapies 2020 20:376

    Content type: Research article

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  24. Annona muricata L. was identified as a popular medicinal plant in treatment regimens among cancer patients in Jamaica by a previously conducted structured questionnaire. Ethnomedically used plant parts, were exam...

    Authors: Kimberley Foster, Omolola Oyenihi, Sunelle Rademan, Joseph Erhabor, Motlalepula Matsabisa, James Barker, Moses K. Langat, Amy Kendal-Smith, Helen Asemota and Rupika Delgoda

    Citation: BMC Complementary Medicine and Therapies 2020 20:375

    Content type: Research article

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  25. This study aimed to evaluate the effects of the Acorus tatarinowii Schott [Shi Chang Pu (SCP)] extract administered at the start of 2 h of middle cerebral artery occlusion (MCAo), followed by 3 d of reperfusion, ...

    Authors: Yu-Chen Lee, Shung-Te Kao and Chin-Yi Cheng

    Citation: BMC Complementary Medicine and Therapies 2020 20:374

    Content type: Research article

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  26. 4-Hydroxyisoleucine (4-HIL) is an active ingredient extracted from Trigonella foenum-graecum L., a Chinese traditional herbal medicine, which exerts the efficacy of anti-obesity and anti-diabetes. We previously r...

    Authors: Cong Zhou, Rui Chen, Feng Gao, Jiaoyue Zhang and Furong Lu

    Citation: BMC Complementary Medicine and Therapies 2020 20:373

    Content type: Research article

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  27. The currently available treatments for colorectal cancer (CRC) are often associated with serious side-effects. Therefore, the development of a novel nutraceutical agent may provide an alternative complementary...

    Authors: Abilasha G. Jayathilake, Margaret F. Veale, Rodney Brain Luwor, Kulmira Nurgali and Xiao Q. Su

    Citation: BMC Complementary Medicine and Therapies 2020 20:372

    Content type: Research article

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  28. The water extract of Quercuse infectoria galls (QIG) is the active ingredient of Uyghur medicine Xipayi Kui Jie’an (KJA) which has promising therapeutic effects on Ulcerative Colitis (UC) as an alternative med...

    Authors: Hui Zhang, Yongbing Wang, Jiayang Liu, Kudelaidi Kuerban, Jian Li, Mubarak Iminjan and Li Ye

    Citation: BMC Complementary Medicine and Therapies 2020 20:371

    Content type: Research article

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  29. Insulin resistance could be associated with the development of Alzheimer disease (AD). The neuropathological hallmarks of AD are beta amyloid (Aβ) produced from sequential cleavage initiated by β-secretase and...

    Authors: Chien-Ning Huang, Chau-Jong Wang, Chih-Li Lin, Hsin-Hua Li, An-Ting Yen and Chiung-Huei Peng

    Citation: BMC Complementary Medicine and Therapies 2020 20:370

    Content type: Research article

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  30. Liquidambaris Fructus is the infructescences of Liquidambar formosana Hance and it has been used to treat some breast disease in Traditional Chinese Medicine. In the previous study we found the anti-breast cancer...

    Authors: Ping Qian, Xiao-Ting Mu, Bing Su, Lu Gao and Dong-Fang Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:369

    Content type: Research article

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  31. Polyherbal formula (PHF) contains extract of Sauropus androgynous (L.) Merr., Trigonella foenum-graceum L., and Moringa oleifera Lam. considered to induce galactagogue activity. This research aimed to evaluate th...

    Authors: Mustofa, Fara Silvia Yuliani, Setyo Purwono, Ahmad Hamim Sadewa, Ema Damayanti and Didik Setyo Heriyanto

    Citation: BMC Complementary Medicine and Therapies 2020 20:368

    Content type: Research article

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  32. This study aimed to investigate the mechanism of action of Panax notoginoside (PNS) against lung cancer and inhibition of lung cancer cell proliferation by the drug at different concentrations in a mouse model, c...

    Authors: Jizhou Zhang, Bin Zhou, Song Jin, Zhiyou Huang, Bidong Ma, Qiqi Shao and Wenzong Zhu

    Citation: BMC Complementary Medicine and Therapies 2020 20:367

    Content type: Research article

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  33. The incidence and mortality of breast cancer in women is increasing worldwide. Breast cancer contains a subpopulation of cells known as cancer stem cells (CSCs). The CSCs are believed to be responsible for che...

    Authors: Nigatu Tuasha, Daniel Seifu, Endalamaw Gadisa, Beyene Petros and Stina Oredsson

    Citation: BMC Complementary Medicine and Therapies 2020 20:366

    Content type: Research article

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  34. Momordica cochinchinensis (Cucurbitaceae) is a nutritionally and medicinally important fruit restricted to South East Asia with diverse morphological and genetic variations but there is limited information on its...

    Authors: Dilani Wimalasiri, Chaitali Dekiwadia, Siat Yee Fong, Terrence J. Piva and Tien Huynh

    Citation: BMC Complementary Medicine and Therapies 2020 20:365

    Content type: Research article

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  35. Arctium lappa L. root (burdock root) has long been recommended for the treatment of different diseases in traditional Chinese medicine. Burdock root possesses anti-oxidative, anti-inflammatory, anti-cancer, and a...

    Authors: King-Chuen Wu, Hung-Kai Weng, Yun-Shang Hsu, Pin-Jia Huang and Yang-Kao Wang

    Citation: BMC Complementary Medicine and Therapies 2020 20:364

    Content type: Research article

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  36. To determine similarities and differences in the reasons for using or not using complementary and alternative medicine (CAM) amongst general and condition-specific populations, and amongst populations in each ...

    Authors: Mayuree Tangkiatkumjai, Helen Boardman and Dawn-Marie Walker

    Citation: BMC Complementary Medicine and Therapies 2020 20:363

    Content type: Research article

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  37. Gandi capsule is a traditional Chinese herbal formula used to promote blood circulation and removing blood stasis in clinical. Our previous study has shown that it reduces proteinuria with routine treatment in...

    Authors: Qiqiang Zhang, Qing Ye, Xiaohui Huang, Ajing Xu, Yan Liu, Jia Qi, Hai Zhang and Jian Zhang

    Citation: BMC Complementary Medicine and Therapies 2020 20:362

    Content type: Research article

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  38. Identifying topics and assessing the reporting quality of Traditional Chinese Medicine (TCM) cohort studies.

    Authors: Yuting Duan, Zhirui Xu, Jingjing Deng, Yanjia Lin, Yan Zheng, Juexuan Chen, Xiaoyu Tang, Xuan Zhang, Chunzhi Tang, Jiangxia Miao and Zhaoxiang Bian

    Citation: BMC Complementary Medicine and Therapies 2020 20:361

    Content type: Research article

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  39. Dental caries and periodontal disease are the most common chronic infectious oral diseases in the world. Acacia nilotica was commonly known in Sudan as Garad or Sunt has a wide range of medicinal uses. In the pre...

    Authors: Ali Mahmoud Muddathir, Ebtihal Abdalla M. Mohieldin and Tohru Mitsunaga

    Citation: BMC Complementary Medicine and Therapies 2020 20:360

    Content type: Research article

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  40. Mangosteen, Garciniam angostana L., is a juicy fruit commonly found in Thailand. The rinds of Garciniam angostana L.have been used as a traditional medicine for the treatment of trauma, diarrhea and skin infec...

    Authors: P. Rukthong, N. Sereesongsang, T. Kulsirirat, N. Boonnak and K. Sathirakul

    Citation: BMC Complementary Medicine and Therapies 2020 20:359

    Content type: Research article

    Published on:

  41. Diarrhoea is a major health issue in both humans and animals and may be caused by bacterial, viral and fungal infections. Previous studies highlighted excellent activity of Newtonia buchananii and N. hildebrandti...

    Authors: Katlego E. Motlhatlego, Muna Ali Abdalla, Carmen M. Leonard, Jacobus N. Eloff and Lyndy J. McGaw

    Citation: BMC Complementary Medicine and Therapies 2020 20:358

    Content type: Research article

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  42. Non-healing wounds have been a severe issue in the global healthcare system. Regrettably, royal jelly, a traditional remedy for various skin injuries, has not been widely applied in cutaneous wounds in clinica...

    Authors: Yan Lin, Meng Zhang, Luying Wang, Tianxing Lin, Guanggao Wang, Jianhua Peng and Songkun Su

    Citation: BMC Complementary Medicine and Therapies 2020 20:357

    Content type: Research article

    Published on:

  43. The present study establishes the cardioprotective role of Thraatchathi Chooranam (TC), a polyherbal traditional Siddha medicine, in terms of membrane stabilizing and antioxidant properties in isoproterenol (I...

    Authors: Ramakrishnan Ganapathy, Anita Ramachandran, Sushmitha Basavapattana Shivalingaiah, Muhammed Bishir, Saravanan Bhojaraj, Shivashree Sridhar, Surapaneni Krishna Mohan, Vishnu Priya Veeraraghavan, Saravana Babu Chidambaram, Musthafa Mohamed Essa and M. Walid Qoronfleh

    Citation: BMC Complementary Medicine and Therapies 2020 20:356

    Content type: Research article

    Published on:

  44. Colon cancer is the third most deadly and one of the most diagnosed diseases in the world. Although routine screening and early detection during last decades has improved the survival, colon cancer still claim...

    Authors: Vinod kumar Nelson, Nalini Kanta Sahoo, Madhusmita Sahu, Hari hara Sudhan, Chitikela P. Pullaiah and Kanuri Sai Muralikrishna

    Citation: BMC Complementary Medicine and Therapies 2020 20:355

    Content type: Research article

    Published on:

  45. An external herbal dispensary (EHD) is a type of pharmacy that provides various types of personalized herbal medicines (PHMs) to other traditional Korean medicine (TKM) institutions. Such dispensaries were leg...

    Authors: Soo-Hyun Sung, Ji-Eun Han, Ji-Yeon Ryu, Angela Dong-Min Sung, Jung-Youn Park, In-Hyuk Ha, Kyeong Han Kim, Jang-Kyung Park and Byung-Cheul Shin

    Citation: BMC Complementary Medicine and Therapies 2020 20:354

    Content type: Research article

    Published on:

  46. Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by severe acute respiratory syndrome coronavirus 2, and responsible for a global pandemic. Despite there being no known vaccines or medi...

    Authors: Jeremy Y. Ng

    Citation: BMC Complementary Medicine and Therapies 2020 20:353

    Content type: Research article

    Published on:

  47. Boswellia sacra resin has been commonly used as analgesic, antimicrobial, and anti-inflammatory properties, which reflect its immunomodulatory activity. Dendritic cells (DCs) are specialized antigen-presenting ce...

    Authors: Alia M. Aldahlawi, Amani T. Alzahrani and Mohamed F. Elshal

    Citation: BMC Complementary Medicine and Therapies 2020 20:352

    Content type: Research article

    Published on:

  48. This study aimed to identify the key genes and KEGG pathways in Carthamus tinctorius L. (Safflower) and Salvia miltiorrhiza Burge. (Salvia) for the treatment of cardio-cerebrovascular disease, and to explore thei...

    Authors: Yu Wang, Yajun Shi, Junbo Zou, Xiaofei Zhang, Yulin Liang, Jia Tai, Chunli Cui, Mei Wang and Dongyan Guo

    Citation: BMC Complementary Medicine and Therapies 2020 20:351

    Content type: Research article

    Published on:

  49. Tangzhiqing (TZQ), as a potential α-glycosidase inhibitor, possesses postprandial hypoglycaemic effects on maltose in humans. The aim of this study was to investigate the mechanisms by which TZQ attenuates pos...

    Authors: Yanfen Li, Xiaomao Zhang, Ruihua Wang, Lu Han, Wei Huang, Hong Shi, Baohe Wang, Ziqiang Li and Shaolan Zou

    Citation: BMC Complementary Medicine and Therapies 2020 20:350

    Content type: Research article

    Published on:

  50. Australians report consulting with a naturopaths or herbalists to improve their wellbeing, yet little is known about the associations between these consultations and the patients’ health behaviours. This cross...

    Authors: Amie Steel, Stefania Tiveron, Rebecca Reid, Jon Wardle, Holger Cramer, Jon Adams, David Sibbritt and Romy Lauche

    Citation: BMC Complementary Medicine and Therapies 2020 20:349

    Content type: Research article

    Published on:

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