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  1. The study was planned to investigate the phytochemicals, antidiabetic and antioxidant studies of A. consanguineum.

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Ali O. Alqarni, Bandar A. Alyami, Omaish S. Alqahtani, Muhammad Saeed Jan, Fida Hussain, Zia Ul Islam, Farhat Ullah, Muhammad Ayaz, Muhammad Abbas, Umer Rashid and Abdul Sadiq
    Citation: BMC Complementary Medicine and Therapies 2022 22:154
  2. Gout is a common disease with high incidence due to unhealthy diet and living habits. Simiao Powder, as a classic formula consisted of four common herbs, has been widely used in clinical practice since ancient...

    Authors: Huachong Xu, Jialin Wu, Shiqi Wang, Lu Xu, Pei Liu, Yucong Shi, Sizhi Wu, Li Deng and Xiaoyin Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:152
  3. Asthma and idiopathic pulmonary fibrosis (IPF) are common chronic diseases of the respiratory system in clinical practice. However, the relationship and molecular links remain unclear, and the current treatmen...

    Authors: Yuanyuan Zhong, Lingli Hu, Wenjing Chen, Bin Wang, Jing Sun and Jingcheng Dong
    Citation: BMC Complementary Medicine and Therapies 2022 22:151
  4. Endometrial carcinoma is one of the two cancers with rising mortality and morbidity in recent years. In the light of many controversies about its treatment, it is urgent to construct a new prognostic model and...

    Authors: Zhiheng Lin, Xiaohui Sui, Wenjian Jiao, Ying Wang and Junde Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:150
  5. Antimicrobial peptides (AMPs) are important effectors of the innate defense system. Cathelicidins, (CRAMP in mouse/rat, LL-37 in human) is one of the two major classes of AMPs in humans. The upregulation of LL...

    Authors: Nagat Siednamohammeddeen, Rehab Badi, Tahane Mohammeddeen, Khalid Enan and AmalSaeed
    Citation: BMC Complementary Medicine and Therapies 2022 22:149
  6. Massage is a widely acceptable and popular form of complementary medicine (CM) among Australian women. While there is some research that reports on massage use in younger women, there is minimal research explo...

    Authors: Suzy Ladanyi, Jon Adams and David Sibbritt
    Citation: BMC Complementary Medicine and Therapies 2022 22:148
  7. Gao-Zi-Yao has long been a unique way for treating various diseases. The present study is to explore the effect of Gao-Zi-Yao on learning and memory function in old spontaneous hypertensive rats (SHR) and its ...

    Authors: Meng-Xiao Han, Wen-Yi Jiang, Yan Jiang, Lin-Hui Wang, Rong Xue, Guo-Xing Zhang and Jing-Wei Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:147
  8. Herbal medicines are widely used in the world especially in developing countries. Pregnant women use herbal products to treat pregnancy related illnesses due to prior experience of herbal medicine use and easy...

    Authors: Yaschilal Muche Belayneh, Tewodros Yoseph and Solomon Ahmed
    Citation: BMC Complementary Medicine and Therapies 2022 22:146
  9. Use of natural products has been proposed as an efficient method in modulation of immune system and treatment of cancers. The aim of this study was to investigate the potential of cryptotanshinone (CPT), narin...

    Authors: Shokoofe Noori, Mitra Nourbakhsh, Hossein Imani, Niloofar Deravi, Niloufar Salehi and Zohreh Abdolvahabi
    Citation: BMC Complementary Medicine and Therapies 2022 22:145
  10. Chronic exposure to ultraviolet B (UVB) causes a series of adverse skin reactions, such as erythema, sunburn, photoaging, and cancer, by altering signaling pathways related to inflammation, oxidative stress, a...

    Authors: Bei Chen, Honghong Chen, Haidong Qu, Kun Qiao, Min Xu, Jingna Wu, Yongchang Su, Yan Shi, Zhiyu Liu and Qin Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:144
  11. Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum) essential oils are two medicinally important plant-derived substances with a wide range of biological properties. Besides, nanoemulsion-based gels ...

    Authors: Fariba Esmaeili, Masoumeh Zahmatkeshan, Yaser Yousefpoor, Hiva Alipanah, Ehsan Safari and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:143
  12. The potential of essential oils (EOs) and of their principal constituents for eradication of biofilm and at the same time the research of new potential acetylcholinesterase inhibitors is gaining increasing int...

    Authors: Lucia Caputo, Francesca Capozzolo, Giuseppe Amato, Vincenzo De Feo, Florinda Fratianni, Giovanni Vivenzio and Filomena Nazzaro
    Citation: BMC Complementary Medicine and Therapies 2022 22:142
  13. Diabetic retinopathy (DR), one of the most common and severe microvascular complication of diabetes mellitus (DM), is mainly caused by diabetic metabolic disorder. So far, there is no effective treatment for D...

    Authors: Yao Chen, Jiaojiao Sun, Zhiyun Zhang, Xiaotong Liu, Qiaozhi Wang and Yang Yu
    Citation: BMC Complementary Medicine and Therapies 2022 22:141

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:153

  14. Mosquito-borne diseases such as malaria and encephalitis are still the cause of several hundred thousand deaths annually. The excessive use of chemical insecticides for transmission control has led to environm...

    Authors: Alireza Sanei-Dehkordi, Mohammad Djaefar Moemenbellah-Fard, Mostafa Saffari, Elham Zarenezhad and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:140
  15. Crinum latifolium L. (Amaryllidaceae) has been used in Southeast Asian traditional medicine to alleviate the symptoms of benign prostatic hyperplasia (BPH). The pathological mechanism of BPH is associated with th...

    Authors: Wisuwat Thongphichai, Tamonwan Uttarawichien, Pithi Chanvorachote, Supaporn Pitiporn, Todsaphol Charoen-ame, Pakakrong Kwankhao, Pasarapa Towiwat and Suchada Sukrong
    Citation: BMC Complementary Medicine and Therapies 2022 22:139
  16. Alleviating suffering and improving quality of life are universally shared goals. In this context, we implemented a pilot study to assess the feasibility and acceptability of a mindfulness intervention in the ...

    Authors: Virginie Prevost, Sophie Lefevre-Arbogast, Alexandra Leconte, Claire Delorme, Sandrine Benoit, Titi Tran and Bénédicte Clarisse
    Citation: BMC Complementary Medicine and Therapies 2022 22:138
  17. Cancer-related incidence and mortality rates are rapidly increasing worldwide. However, no studies have examined the effect of cancer as a single factor on the use of traditional, complementary, and alternativ...

    Authors: Dongsu Kim, Soo-Hyun Sung, Seungwon Shin and Minjung Park
    Citation: BMC Complementary Medicine and Therapies 2022 22:137
  18. Authors: Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai and Hsiu Mei Hsieh-Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:136

    The original article was published in BMC Complementary Medicine and Therapies 2021 21:259

  19. Trachyspermum ammi, commonly known as Ajwain, is a member of the Apiaceae family. It is a therapeutic herbal spice with diverse pharmacological properties, used in traditional medicine for various ailments. Howev...

    Authors: Saud O. Alshammari, Taibah Aldakhil, Qamar A. Alshammari, David Salehi and Aftab Ahmed
    Citation: BMC Complementary Medicine and Therapies 2022 22:135
  20. The genus Eryngium is a member of the Apiaceae family that has shown different pharmacological effects mainly including anti-inflammatory, analgesic, anti-cancer, hepatoprotective, and anti-oxidant. Previous r...

    Authors: Haleh Forouhandeh, Zahra Rezaei Param, Ommoleila Molavi, Parina Asgharian and Vahideh Tarhriz
    Citation: BMC Complementary Medicine and Therapies 2022 22:134
  21. The blood-testis barrier (BTB) is a physical barrier of the testis to prevent various exogenous substrates from entering apical compartments and provides immune privilege for spermatogenesis, which is essentia...

    Authors: Junjun Li, Yaodong You, Peihai Zhang, Xiaopeng Huang, Liang Dong, Fang Yang, Xujun Yu and Degui Chang
    Citation: BMC Complementary Medicine and Therapies 2022 22:133
  22. Cordyceps species have been used as tonics to enhance energy, stamina, and libido in traditional Asian medicine for more than 1600 years, indicating their potential for improving reproductive hormone disorders an...

    Authors: Dongyeop Jang, Eunjoo Lee, Sullim Lee, Yongsam Kwon, Ki Sung Kang, Chang-Eop Kim and Daeyoung Kim
    Citation: BMC Complementary Medicine and Therapies 2022 22:132
  23. Cognitive health is of great interest to society, with neuroinflammation and systemic inflammation age-related risk factors that are linked to declines in cognitive performance. Several botanical ingredients h...

    Authors: Gemma Margetts, Sotirios Kleidonas, Nawel S. Zaibi, Mohamed S. Zaibi and Kieron D. Edwards
    Citation: BMC Complementary Medicine and Therapies 2022 22:131
  24. Medicinal plants have been successfully used as an alternative source of drugs for the treatment of microbial diseases. Finding a novel treatment for malaria is still challenging, and various extracts from dif...

    Authors: Ahmed M. Abdou, Abdel-latif S. Seddek, Noha Abdelmageed, Mohamed O. Badry and Yoshifumi Nishikawa
    Citation: BMC Complementary Medicine and Therapies 2022 22:130
  25. Jianpi Qinghua Fomula (JPQHF), a clinically proven prescription,has been applied to cure insulin resistance(IR) and type 2 diabetes (T2DM) for more than 20 years. Here, we will unravel the underlying molecular...

    Authors: Yahua Liu, Xu Han, Mengjie Cai, Shenyi Jin, Zihui Yan, Hao Lu and Qingguang Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:129
  26. Complementary and alternative medicine (CAM) is defined as a group of diverse medical and healthcare practices outside of conventional medicine modalities. The use of CAM is steadily increasing despite gaps in...

    Authors: Brittany R. Odegard, Mollie R. Ferguson, Farah Naja, Jennifer Ayoub and Jinan Banna
    Citation: BMC Complementary Medicine and Therapies 2022 22:128
  27. The International Cohort on Lifestyle Determinants of Health (INCLD Health) is an ongoing, prospective cohort study assessing the health behaviours and lifestyles of higher education students, including their ...

    Authors: Adam Sadowski, Ryan S. Wexler, Douglas Hanes, Lita Buttolph, Tediana Torrens, Jillian Moehle, Hadil Sarrar, Joanna Harnett, David T. Zava and Ryan Bradley
    Citation: BMC Complementary Medicine and Therapies 2022 22:127
  28. Home remedies are anchored in patients’ everyday life, but their use in Western cultures remains scarcely explored. Our objectives were to investigate primary care patients’ perspectives and use of non-pharmac...

    Authors: Neria E. Winkler, Paul Sebo, Dagmar M. Haller and Hubert Maisonneuve
    Citation: BMC Complementary Medicine and Therapies 2022 22:126
  29. The current drug treatments for benign prostatic hyperplasia (BPH) have negative side effects. Therefore, it is important to find effective alternative therapies with significantly fewer side effects. Our prev...

    Authors: Guifang Huang, Xiao He, Zesheng Xue, Yiming Long, Jiakuan Liu, Jinming Cai, Pengfei Tang, Bangmin Han, Bing Shen, Ruimin Huang and Jun Yan
    Citation: BMC Complementary Medicine and Therapies 2022 22:125
  30. Bacteria-mediated cancer immunotherapy (BCI) robustly stimulates the immune system and represses angiogenesis, but tumor recurrence and metastasis commonly occur after BCI. The natural product Ilex kudingcha C. J...

    Authors: Haixia Xu, Linghua Piao, Xiande Liu and Sheng-nan Jiang
    Citation: BMC Complementary Medicine and Therapies 2022 22:123
  31. Toxoplasmosis is caused by an intracellular zoonotic protozoan, Toxoplasma gondii, which could be lethal in immunocompromised patients. This study aimed to synthesize Neem oil-loaded solid lipid nanoparticles (Ne...

    Authors: Sara Nemati, Hanieh Mohammad Rahimi, Zahra Hesari, Meysam Sharifdini, Nooshin Jalilzadeh Aghdam, Hamed Mirjalali and Mohammad Reza Zali
    Citation: BMC Complementary Medicine and Therapies 2022 22:122
  32. Rheum tanguticum (R. tanguticum) is an edible and medicinal plant that exhibits high antioxidant activity. The purpose of the present study was to investigate the bioactive components of its seeds and the potent...

    Authors: Lingling Wang, Feng Xiong, Shuo Zhao, Yang Yang and Guoying Zhou
    Citation: BMC Complementary Medicine and Therapies 2022 22:121
  33. Scutellaria barbata D.Don (SBD) is derived from the dried whole plant of Labiate which has been widely used to treat patients with multiple cancer. It was previously reported that the ethanol extract of SBD is...

    Authors: Dongya Sheng, Bei Zhao, Wenjing Zhu, Tiantian Wang and Yu Peng
    Citation: BMC Complementary Medicine and Therapies 2022 22:120
  34. Interstitial cystitis (IC) has a chronic chemical irritation and inflammation of non-bacterial origin in the bladder wall leading to various severe symptoms. There is evidence that chronic inflammation is signifi...

    Authors: Adrienn Horváth, Edina Pandur, Katalin Sipos, Giuseppe Micalizzi, Luigi Mondello, Andrea Böszörményi, Péter Birinyi and Györgyi Horváth
    Citation: BMC Complementary Medicine and Therapies 2022 22:119
  35. Although the vast majority of cancer patients use natural health products (NHPs), 59% of oncology healthcare providers (HCP) report not receiving any education on NHPs. KNOWintegrativeoncology.org (KNOW) is a ...

    Authors: Jen Green, Heather Wright, Dugald Seely, Mark Legacy, Maureen Anderson, Hallie Armstrong, Casey Martell, Sarah Soles and Lynda G. Balneaves
    Citation: BMC Complementary Medicine and Therapies 2022 22:118
  36. Lipotropic molecules are effective therapeutic targets to counteract non-alcoholic fatty liver disease (NAFLD). Lipotropic compounds are capable of removing fat from the liver and/or manage the reduction of th...

    Authors: Leila Sandra Nnanga, Bruno Dupon Akamba Ambamba, Fils Armand Ella, Damaris Enyegue Mandob and Judith Laure Ngondi
    Citation: BMC Complementary Medicine and Therapies 2022 22:117
  37. Diosmin has been reported to treat diabetes, but its role in diabetic nephropathy (DN) remains unclear. This research investigated the mechanism by which diosmin alleviated high glucose (HG)-induced HK-2 cell ...

    Authors: Jiuhong Deng, Chao Zheng, Zhou Hua, Haideng Ci, Guiying Wang and Lijing Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:116
  38. Trans-cinnamaldehyde (TCA) is one of the main pharmaceutical ingredients of Cinnamomum cassia Presl, which has been shown to have therapeutic effects on a variety of cardiovascular diseases. This study was carrie...

    Authors: Dongdong Qian, Jing Tian, Sining Wang, Xiaoli Shan, Pei Zhao, Huihua Chen, Ming Xu, Wei Guo, Chen Zhang and Rong Lu
    Citation: BMC Complementary Medicine and Therapies 2022 22:115
  39. Viral infections have a history of abrupt and severe eruptions through the years in the form of pandemics. And yet, definitive therapies or preventive measures are not present. Herbal medicines have been a sou...

    Authors: Madiha Haider, Vivek Anand, M. Ghalib Enayathullah, Yash Parekh, Sushma Ram, Surekha Kumari, Anmol, Gayatri Panda, Manjari Shukla, Dhwani Dholakia, Arjun Ray, Sudipta Bhattacharyya, Upendra Sharma, Kiran Kumar Bokara, Bhavana Prasher and Mitali Mukerji
    Citation: BMC Complementary Medicine and Therapies 2022 22:114
  40. Traditional Chinese medicine (TCM) and Western medicine are available and have a long history in Hong Kong. Little is known on the intention to use TCM in Hong Kong. In this study, the intention to use TCM was...

    Authors: Tommy K. C. Ng, Man Fung Lo, Ben Y. F. Fong and Hilary H. L. Yee
    Citation: BMC Complementary Medicine and Therapies 2022 22:113
  41. The compound Danshen Dripping Pill (CDDP), which is a mixture of extracts from Radix Salviae and Panax notoginseng, is a patented traditional Chinese medicine that is widely used in multiple countries for relievi...

    Authors: Yang-Xi Hu, Hong-Min You, Chang-Zhen Ren, Bo-Wen Hu, Lu-Jun Zhang, Yan-Da Zhang, Zhi-Qing He, Ru Ding, Zhi-Fu Guo and Chun Liang
    Citation: BMC Complementary Medicine and Therapies 2022 22:112
  42. Oral malignancies have a significant effect on the quality of life among the affected patients. Curcumin is an antioxidant with a low bioavailability in the target tissue. Niosomes are carriers of increasing t...

    Authors: Behzad Fazli, Soussan Irani, Hassan Bardania, Mahdieh-Sadat Moosavi and Bita Rohani
    Citation: BMC Complementary Medicine and Therapies 2022 22:109
  43. Alzheimer’s disease (AD) pathogenesis is associated with amyloid-β (Aβ)-induced neuroinflammation. In AD, the activation of microglia caused by Aβ accumulation is followed by the synthesis and release of pro-i...

    Authors: Nutchareeporn Nillert, Chantana Boonyarat, Jariya Umka Welbat, Komsun Bunreungthong, Ploenthip Puthongking and Wanassanun Pannangrong
    Citation: BMC Complementary Medicine and Therapies 2022 22:108
  44. Advances in systems science creates an opportunity to bring a complexity perspective to health care practices and research. While medical knowledge has greatly progressed using a reductionist and mechanistic p...

    Authors: Kim D. Graham, Amie Steel and Jon Wardle
    Citation: BMC Complementary Medicine and Therapies 2022 22:107
  45. Pediatric integrative medicine, combining conventional and complementary medical approaches for children and adolescents, is an integral part of the health care system in Switzerland. However, there is still a...

    Authors: Benedikt M. Huber and Pierre-Yves Rodondi
    Citation: BMC Complementary Medicine and Therapies 2022 22:106
  46. Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the paucity of evidence, various complementary, alternative...

    Authors: Jeremy Y. Ng, Wael Abdelkader and Cynthia Lokker
    Citation: BMC Complementary Medicine and Therapies 2022 22:105
  47. Chinese herbal medicine (CHM) is characterized by “multi- compounds, multi-targets and multi-pathway”, which has advanced benefits for preventing and treating complex diseases, but there still exists unsolved ...

    Authors: Dao-jin Xue, Zheng Zhen, Ke-xin Wang, Jia-lin Zhao, Yao Gao, Yu-peng Chen, You-bi Shen, Zi-zhuang Peng, Dao-gang Guan and Tao Huang
    Citation: BMC Complementary Medicine and Therapies 2022 22:103