Articles
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Citation: BMC Complementary Medicine and Therapies 2023 23:75
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Retraction Note: Astragalin alleviates cerebral ischemia-reperfusion injury by improving anti-oxidant and anti-inflammatory activities and inhibiting apoptosis pathway in rats
Citation: BMC Complementary Medicine and Therapies 2023 23:74 -
Effects of music therapy as an alternative treatment on depression in children and adolescents with ADHD by activating serotonin and improving stress coping ability
The objective of this study was to determine the effect of music therapy as an alternative treatment on depression in children and adolescents with attention-deficit hyperactivity disorder (ADHD) by activating...
Citation: BMC Complementary Medicine and Therapies 2023 23:73 -
Protective effects of baicalin magnesium on non-alcoholic steatohepatitis rats are based on inhibiting NLRP3/Caspase-1/IL-1β signaling pathway
Baicalin magnesium is a water-soluble compound isolated from the aqueous solution by Scutellaria baicalensis Georgi. Preliminary experiments have demonstrated that baicalin magnesium can exert protective effects ...
Citation: BMC Complementary Medicine and Therapies 2023 23:72 -
Senna occidentalis (L.) Link root extract inhibits Plasmodium growth in vitro and in mice
Senna occidentalis (L.) Link has been used worldwide in traditional treatment of many diseases and conditions including snakebite. In Kenya, a decoction from the plant roots taken orally, is used as a cure for ma...
Citation: BMC Complementary Medicine and Therapies 2023 23:71 -
Clinical associations for traditional and complementary medicine use among Norwegian cancer survivors in the seventh survey of the Tromsø study: a cross-sectional study
Cancer survivors are a diverse group with varying needs that are patient-, disease-, and/or treatment-specific. Cancer survivors have reported supplementing conventional anti-cancer treatment with Traditional ...
Citation: BMC Complementary Medicine and Therapies 2023 23:70 -
Thymoquinone, piperine, and sorafenib combinations attenuate liver and breast cancers progression: epigenetic and molecular docking approaches
Traditional herbal medicine has been used for centuries to cure many pathological disorders, including cancer. Thymoquinone (TQ) and piperine (PIP) are major bioactive constituents of the black seed (Nigella sati...
Citation: BMC Complementary Medicine and Therapies 2023 23:69 -
Correction: Protective effects of Xinji′erkang on myocardial infarction induced cardiac injury in mice
An amendment to this paper has been published and can be accessed via the original article.
Citation: BMC Complementary Medicine and Therapies 2023 23:68 -
Research on the wound healing effect of Shengji Huayu Formula ethanol extract-derived fractions in streptozotocin-induced diabetic ulcer rats
Diabetic ulcer is a common complication of diabetes. It is characterized by a long-term disease course and high recurrence rate. Shengji Huayu Formula (SHF) is an effective formula for treating diabetic ulcers...
Citation: BMC Complementary Medicine and Therapies 2023 23:67 -
The effects of foot reflexology on symptoms of discomfort in palliative care: a feasibility study
In palliative care, the relief of discomfort is sought by an overall approach, combining prescribed medication and additional therapies, such as foot reflexology (FR). The main objective of this study was to a...
Citation: BMC Complementary Medicine and Therapies 2023 23:66 -
Correction: Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions
Citation: BMC Complementary Medicine and Therapies 2023 23:65 -
Plantamajoside alleviates hypoxia-reoxygenation injury through integrin-linked kinase/c-Src/Akt and the mitochondrial apoptosis signaling pathways in H9c2 myocardial cells
Myocardial ischemia–reperfusion injury(MIRI) is one of the common complications after myocardial infarction surgery, Oxidative stress is among the main mechanisms of myocardial ischemia–reperfusion injury. Pla...
Citation: BMC Complementary Medicine and Therapies 2023 23:64 -
Neuroimaging studies of acupuncture on Alzheimer’s disease: a systematic review
Acupuncture effectively improves cognitive function in Alzheimer’s disease (AD). Many neuroimaging studies have found significant brain alterations after acupuncture treatment of AD, but the underlying central...
Citation: BMC Complementary Medicine and Therapies 2023 23:63 -
Baicalein alleviates fibrosis and inflammation in systemic sclerosis by regulating B-cell abnormalities
Systemic sclerosis (SSc; also known as “scleroderma”) is an autoimmune disorder characterized by extensive fibrosis, vascular changes, and immunologic dysregulation. Baicalein (phenolic flavonoid derived from Scu...
Citation: BMC Complementary Medicine and Therapies 2023 23:62 -
Antibacterial activity of oregano essential oils against Streptococcus mutans in vitro and analysis of active components
Streptococcus mutans (S. mutans) is considered the most relevant bacteria during the transition of the non-pathogenic commensal oral microbial community to plaque biofilms that promote the development of dental c...
Citation: BMC Complementary Medicine and Therapies 2023 23:61 -
A multi-target protective effect of Danggui-Shaoyao-San on the vascular endothelium of atherosclerotic mice
Atherosclerosis (AS) is a chronic disease characterized by abnormal blood lipid metabolism, inflammation and vascular endothelial injury. Vascular endothelial injury is the initial stage during the occurrence ...
Citation: BMC Complementary Medicine and Therapies 2023 23:60 -
Correction: Potent hepatoprotective activity of common rattan (Calamus rotang L.) leaf extract and its molecular mechanism
Citation: BMC Complementary Medicine and Therapies 2023 23:59 -
Efficacy and safety of Obex® in overweight and obese subjects: a randomised, double-blind, placebo-controlled clinical trial
Obex® may be helpful in reducing body weight and fat. The current study was carried out to evaluate the efficacy and safety of Obex® in the treatment of overweight and obese subjects.
Citation: BMC Complementary Medicine and Therapies 2023 23:58 -
Efficacy and safety of topical 0.1% cannabidiol for managing recurrent aphthous ulcers: a randomized controlled trial
Although topical steroids constitute the first-line therapy for recurrent aphthous ulcers (RAUs), their long-term use often leads to candidiasis. Although cannabidiol (CBD) can be an alternative for pharmacolo...
Citation: BMC Complementary Medicine and Therapies 2023 23:57 -
Angiotensin converting enzyme (ACE) inhibitors activity from purified compounds Fructus Phaleria macrocarpa (Scheff) Boerl
Mahkota Dewa [Phaleria macrocarpa (Scheff) Boerl.] fruit in vitro and in- vivo can decrease and prevent elevation of the blood pressure, lower plasma glucose levels, possess an antioxidant effect, and recover liv...
Citation: BMC Complementary Medicine and Therapies 2023 23:56 -
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway
Age-related macular degeneration (AMD) is a leading cause of vision loss in elderly people, and dry AMD is the most common type of AMD. Oxidative stress and alternative complement pathway activation may play e...
Citation: BMC Complementary Medicine and Therapies 2023 23:55 -
The efficacy and safety of Chinese herbal medicine Guizhi Fuling capsule combined with low dose mifepristone in the treatment of uterine fibroids: a systematic review and meta-analysis of 28 randomized controlled trials
Guizhi Fuling Capsule (GZFL), a classic traditional Chinese medicine prescription, is often recommended for the treatment of uterine fibroids (UFs). However, the efficacy and safety of GZFL in combination with...
Citation: BMC Complementary Medicine and Therapies 2023 23:54 -
Experience of parents in delivering pediatric tuina to children with symptoms of attention deficit hyperactivity disorder during the COVID-19 pandemic: qualitative findings from focus group interviews
Evidence suggests that pediatric tuina, a modality of traditional Chinese medicine (TCM), might have beneficial effects on the symptoms of attention deficit hyperactivity disorder (ADHD), such as overall improvem...
Citation: BMC Complementary Medicine and Therapies 2023 23:53 -
The effect of zingiber officinale on prooxidant-antioxidant balance and glycemic control in diabetic patients with ESRD undergoing hemodialysis: a double-blind randomized control trial
Diabetes management in hemodialysis patients with end-stage renal disease needs precision to avoid complications. The study aimed to investigate the effect of ginger supplementation on prooxidant-antioxidant b...
Citation: BMC Complementary Medicine and Therapies 2023 23:52 -
Use of CAM among cancer patients
The use of complementary and alternative medicine (CAM) by patients is widespread. However, there is a lack of knowledge regarding the extent and details of patient CAM use in Sweden, especially in rural Swede...
Citation: BMC Complementary Medicine and Therapies 2023 23:51 -
Correction: A novel therapeutic effect of mannitol-rich extract from the brown seaweed Sargassum ilicifolium using in vitro and in vivo models
Citation: BMC Complementary Medicine and Therapies 2023 23:50 -
Encapsulation of Polygonum bistorta root phenolic compounds as a novel phytobiotic and its protective effects in the mouse model of enteropathogenic Escherichia coli infection
Microencapsulation technology is the fundamental delivery system for encapsulating the natural bioactive compounds especially phenolic in order to developing bioavailability, stability and controlling release....
Citation: BMC Complementary Medicine and Therapies 2023 23:49 -
Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines
Cancer remains a global health concern and constitutes an important barrier to increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many clinical therapeutic failures. The imp...
Citation: BMC Complementary Medicine and Therapies 2023 23:48 -
In vitro and in vivo antiplasmodial activities of leaf extracts from Sonchus arvensis L.
Malaria continues to be a global problem due to the limited efficacy of current drugs and the natural products are a potential source for discovering new antimalarial agents. Therefore, the aims of this study ...
Citation: BMC Complementary Medicine and Therapies 2023 23:47 -
The effects of aqueous and ethanolic extracts of Rheum ribes on insulin-resistance and apolipoproteins in patients with type 2 diabetes mellitus: a randomized controlled trial
Previous studies have shown that Rheum ribes (R. ribes) could be effective in controlling the blood glucose levels. This study was conducted to determine the effects of R. ribes supplementation on glycemic indice...
Citation: BMC Complementary Medicine and Therapies 2023 23:46 -
In utero and postnatal exposure to Foeniculum vulgare and Linum usitatissimum seed extracts: modifications of key enzymes involved in epigenetic regulation and estrogen receptors expression in the offspring’s ovaries of NMRI mice
Early-life exposure to exogenous estrogens such as phytoestrogens (plant-derived estrogens) could affect later health through epigenetic modifications. Foeniculum vulgare (fennel) and Linum usitatissimum (flax) a...
Citation: BMC Complementary Medicine and Therapies 2023 23:45 -
Decoding the underlying mechanisms of Di-Tan-Decoction in treating intracerebral hemorrhage based on network pharmacology
Chinese medicine usually acts as "multi-ingredients, multi-targets and multi-pathways" on complex diseases, and these action modes reflect the coordination and integrity of the treatment process with tradition...
Citation: BMC Complementary Medicine and Therapies 2023 23:44 -
In vitro antioxidant, anti-inflammatory, and anticancer activities of mixture Thai medicinal plants
The phytochemical study of medicinal plants is rapidly gaining popularity with many pharmacologic effects. This study aims to determine the antioxidant capacity as well as anticancer and antimigration activiti...
Citation: BMC Complementary Medicine and Therapies 2023 23:43 -
Antibacterial efficacy of indigenous Pakistani honey against extensively drug-resistant clinical isolates of Salmonella enterica serovar Typhi: an alternative option to combat antimicrobial resistance
Extensively drug-resistant (XDR) Salmonella enterica serovar Typhi (S. Typhi) poses a grave threat to public health due to increased mortality and morbidity caused by typhoid fever. Honey is a promising antibacte...
Citation: BMC Complementary Medicine and Therapies 2023 23:42 -
The prevalence and predictors of herb-drug interactions among Iranian cancer patients during chemotherapy courses
The concurrent usage of herbal medicines with conventional therapies is an important concern in cancer treatment which can lead to unexpected consequences like herb-drug interactions. This study aimed to deter...
Citation: BMC Complementary Medicine and Therapies 2023 23:41 -
Correction: Effects of Vitellaria paradoxa (C.F. Gaertn.) Aqueous leaf extract administration on Salmonella typhimurium-infected rats
Citation: BMC Complementary Medicine and Therapies 2023 23:40 -
Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against dihydropteroate synthase
One of the main challenges of wound healing is infection with multi-drug resistant (MDR) bacteria such as Staphylococcus aureus. The spectrum of antibiotics used to treat them is declining; thus, there is a need ...
Citation: BMC Complementary Medicine and Therapies 2023 23:39 -
Effects of Baduanjin exercise on the physical function of middle-aged and elderly people: a systematic review and meta-analysis of randomized controlled trials
Chinese mind–body exercise-Baduanjin has received increasing attention for health promotion among middle-aged and older adults in China, but there is a lack of high-quality evidence on its effectiveness. This ...
Citation: BMC Complementary Medicine and Therapies 2023 23:38 -
Benefit-risk assessment of traditional Chinese medicine preparations of sinomenine using multicriteria decision analysis (MCDA) for patients with rheumatoid arthritis
A multicriteria decision analysis (MCDA) model was used to evaluate the benefits and risks of traditional Chinese medicine preparations of sinomenine alone or in combination with conventional drugs in the trea...
Citation: BMC Complementary Medicine and Therapies 2023 23:37 -
Determination of the synergistic anti-influenza effect of Huangqin Su tablet and Oseltamivir and investigation of mechanism of the tablet based on gut microbiota and network pharmacology
Huangqin Su (HQS) tablet is mainly composed of baicalein which has been evaluated for its ability to inhibit influenza. The present study aimed to investigate the effect of HQS and oseltamivir phosphate (OS) (...
Citation: BMC Complementary Medicine and Therapies 2023 23:36 -
Forsythiaside A ameliorates sepsis-induced acute kidney injury via anti-inflammation and antiapoptotic effects by regulating endoplasmic reticulum stress
Sepsis is a systemic inflammatory response syndrome caused by an infection in the body, and accompanying acute kidney injury (AKI) is a common complication of sepsis. It is associated with increased mortality ...
Citation: BMC Complementary Medicine and Therapies 2023 23:35 -
Assessment of the phytochemical composition and antimicrobial properties of Tapinanthus bangwensis leaves hosted by the branches of Persea americana
Medicinal plants represent a valuable source for new effective and safe antimicrobial drugs making them an alternative therapy. Existing antimicrobial agents are costly and mostly associated with possible side...
Citation: BMC Complementary Medicine and Therapies 2023 23:34 -
Tinospora sinensis (Lour.) Merr alkaloid rich extract induces colon cancer cell death via ROS mediated, mTOR dependent apoptosis pathway: “an in-vitro study”
Colorectal cancer (CRC) is the second most mortality rate causing disease after lung cancer. Though there is a significant improvement in the treatment schedule offered to CRC. However, there is no notable dec...
Citation: BMC Complementary Medicine and Therapies 2023 23:33 -
What are the ways in which social media is used in the context of complementary and alternative medicine in the health and medical scholarly literature? a scoping review
Despite the increased use of social media to share health-related information and the substantial impact that complementary and alternative medicine (CAM) can have on individuals’ health and wellbeing, current...
Citation: BMC Complementary Medicine and Therapies 2023 23:32 -
Terminally ill patients’ and their relatives’ experiences and behaviors regarding complementary and alternative medicine utilization in hospice palliative inpatient care units: a cross-sectional, multicenter survey
Terminally ill patients often experience exacerbations of diseases that render mainstream medicine ineffective in relieving symptoms, prompting attempts at complementary and alternative medicine (CAM). This st...
Citation: BMC Complementary Medicine and Therapies 2023 23:31 -
Sub-chronic toxicity of the aqueous leaf extract of Ocimum lamiifolium Hochst. ex Benth on biochemical parameters and histopathology of liver and kidney in rats: in vivo and in- silico toxicity studies
The aerial part of Ocimum lamiifolium is commonly used in Ethiopian traditional medicine. Although this plant is mostly used in traditional medicine, its safety profile has not been documented yet. The aim of thi...
Citation: BMC Complementary Medicine and Therapies 2023 23:30 -
Antioxidant and antiproliferative potentials of phenolic-rich extracts from biotransformed grape pomace in colorectal Cancer
Colorectal carcinoma is one of the most commonly diagnosed malignancies worldwide. Consumption of dietary supplements and nutraceuticals such as phenolic compounds may help combat colorectal carcinoma. The eff...
Citation: BMC Complementary Medicine and Therapies 2023 23:29 -
Analysis of the potential biological mechanisms of Danyu Gukang Pill against osteonecrosis of the femoral head based on network pharmacology
Osteonecrosis of the femoral head (ONFH) is still a challenge for orthopedists worldwide and can lead to disability if patients are not treated effectively. Danyu Gukang Pill (DGP), a traditional Chinese medic...
Citation: BMC Complementary Medicine and Therapies 2023 23:28 -
Exploring new therapeutic potentials of curcumin against post-surgical adhesion bands
Adhesion band formation is a common cause of morbidity for patients undergoing surgeries. Anti-inflammatory and anti-fibrotic properties of curcumin, a pharmacologically active component of Curcuma longa, have be...
Citation: BMC Complementary Medicine and Therapies 2023 23:27 -
A novel therapeutic effect of mannitol-rich extract from the brown seaweed Sargassum ilicifolium using in vitro and in vivo models
Wound healing is an active, complex, integrated series of cellular, physiological, and biochemical changes initiated by the stimulus of injury in a tissue. The present study was performed to investigate the po...
Citation: BMC Complementary Medicine and Therapies 2023 23:26