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  1. The emergence of antimalarial drug resistance encourages the search for new antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a medicinal plant that is used in traditional Thai ...

    Authors: Prapaporn Chaniad, Arnon Chukaew, Apirak Payaka, Arisara Phuwajaroanpong, Tachpon Techarang, Walaiporn Plirat and Chuchard Punsawad
    Citation: BMC Complementary Medicine and Therapies 2022 22:266
  2. The development of multidrug resistance (MDR) associated with the overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes antifungal therapies. The urgent need for novel agents able to ...

    Authors: Florimar Gil, Jerónimo Laiolo, Brayan Bayona-Pacheco, Richard D. Cannon, Antonio Ferreira-Pereira and María Cecilia Carpinella
    Citation: BMC Complementary Medicine and Therapies 2022 22:264
  3. Complementary medicine (CM) is frequently used by patients, but little is known about the usage of CM in surgical patients. The study aimed to elucidate the relevance of CM in surgery.

    Authors: Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets and Roman Huber
    Citation: BMC Complementary Medicine and Therapies 2022 22:263

    The Correction to this article has been published in BMC Complementary Medicine and Therapies 2022 22:304

  4. Diabetic nephropathy (DN) is one of the most important complications of type 2 diabetes (T2DM). Oxidative stress and inflammatory cytokines play an essential role in the development and progression of DN. Desp...

    Authors: Asma Jaafarinia, Behzad Kafami, Adeleh Sahebnasagh and Fatemeh Saghafi
    Citation: BMC Complementary Medicine and Therapies 2022 22:262
  5. As the largest organ, the skin has been frequently affected by trauma, chemical materials, toxins, bacterial pathogens, and free radicals. Recently, many attempts have been made to develop natural nanogels tha...

    Authors: Fatemeh Rasti, Yaser Yousefpoor, Abbas Abdollahi, Mojdeh Safari, Ghazaal Roozitalab and Mahmoud Osanloo
    Citation: BMC Complementary Medicine and Therapies 2022 22:261
  6. Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa‑Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El‑Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:260

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:227

  7. The leaf of Ceylon cinnamon (true cinnamon) is traditionally claimed for a variety of health benefits. However, reported scientific information is scanty and needs urgent attention for value addition.

    Authors: Walimuni Prabhashini Kaushalya Mendis Abeysekera, Galbada Arachchige Sirimal Premakumara, Wanigasekera Daya Ratnasooriya and Walimuni Kanchana Subhashini Mendis Abeysekera
    Citation: BMC Complementary Medicine and Therapies 2022 22:259
  8. The emergence of drug resistance among pathogens has resulted in renewed interest in bioprospecting for natural microbial products.

    Authors: Tsolanku Sidney Maliehe, Melusi Mbambo, Londeka Sibusisiwe Ngidi, Jabulani Siyabonga Emmanuel Shandu, Ofentse Jacob Pooe, Peter Masoko and Tlou Nelson Selepe
    Citation: BMC Complementary Medicine and Therapies 2022 22:258
  9. Baicalin is a generally available flavonoid with potent biological activity. The present study aimed to assess the underlying mechanism of baicalin in treatment of atherosclerosis (AS) with the help of network...

    Authors: Mingshuang Li and Conglin Ren
    Citation: BMC Complementary Medicine and Therapies 2022 22:257
  10. Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as a wound healing therapy. This study investigated the additive value ...

    Authors: Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar and Hoda A. Elkhenany
    Citation: BMC Complementary Medicine and Therapies 2022 22:256
  11. Diabetic wounds are one of the most important issues in diabetic patients. It seems that Juglans regia L. leaf with antioxidant and anti-inflammatory potentials can be profitable for healing of diabetic wounds. T...

    Authors: Davood Nasiry, Ali Reza Khalatbary, Alireza Ghaemi, Mohammad Ali Ebrahimzadeh and Mohammad Hossein Hosseinzadeh
    Citation: BMC Complementary Medicine and Therapies 2022 22:255
  12. Endometriosis is a common gynecological disease, and its underlying mechanisms remain elusive. Patients are at a higher risk of recurrence after surgery or drug withdrawal. In this study, to identify a potenti...

    Authors: Junde Zhao, Juntao Wang, Jinxing Liu, Shuling Li, Pengfei Liu and Xiaodan Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:254
  13. Epimedii has long been used as a traditional medicine in Asia for the treatment of various common diseases, including Alzheimer's disease, cancer, erectile dysfunction, and stroke. Studies have reported the am...

    Authors: Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li and De-xi Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:253
  14. Traditional, complementary and alternative medicine (TCAM) is used to treat a broad range of conditions. In low- and middle-income countries (LMICs), TCAM use is particularly common among those with low socio-...

    Authors: Lia M. Palileo-Villanueva, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Fadhlina Ab-Majid, Farnaza Ariffin, Dina Balabanova, Mohamad-Rodi Isa, Nafiza Mat-Nasir, Mazapuspavina My, Alicia Renedo, Maureen L. Seguin, Khalid Yusoff, Antonio L. Dans and Martin Mckee
    Citation: BMC Complementary Medicine and Therapies 2022 22:252
  15. Complementary and Integrative Medicine (CIM) is often taken up by individuals seeking relief from different diseases. This study investigates the prevalence and associated factors of CIM use in patients with C...

    Authors: Mohammad Mahdi Parvizi, Sedigheh Forouhari, Reza Shahriarirad, Sepehr Shahriarirad, Ryan D Bradley and Leila Roosta
    Citation: BMC Complementary Medicine and Therapies 2022 22:251
  16. Akt and mTOR are aberrantly activated in cancers and targeting these proteins are interesting for cancer drug discovery. Napabucasin (NB), a phytochemical compound, has been reported as potential anti-cancer a...

    Authors: Korrakod Petsri, Sunisa Thongsom, Satapat Racha, Supakarn Chamni, Saresa Jindapol, Nantawat Kaekratoke, Hongbin Zou and Pithi Chanvorachote
    Citation: BMC Complementary Medicine and Therapies 2022 22:250
  17. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes, α-amylase, and α-glucosidases, in the diges...

    Authors: Haimanot Mitiku, Tae Yang Kim, Hanna Kang, Emmanouil Apostolidis, Jung-Yun Lee and Young-In Kwon
    Citation: BMC Complementary Medicine and Therapies 2022 22:249
  18. Complementary medicine therapists such as traditional acupuncturists are a large resource for supporting public health targets to improve health behaviours. Our objectives were to determine the prevalence and ...

    Authors: J. Pinto, K. Bradbury, D. Newell and F. L. Bishop
    Citation: BMC Complementary Medicine and Therapies 2022 22:248
  19. Black salve is a controversial complementary and alternative medicine (CAM) associated with skin toxicity and skin cancer treatment failures. Black salve formulations vary between manufacturers and contain a n...

    Authors: Andrew Croaker, Arie Davis, Anthony Carroll, Lei Liu and Stephen P. Myers
    Citation: BMC Complementary Medicine and Therapies 2022 22:247
  20. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-016-1470-9.

    Authors: Vikas Kumar, Prakash Chandra Bhatt, Kalicharan Sharma, Mahfoozur Rahman, Dinesh Kumar Patel, Nikunj Sethi, Atul Kumar, Nikhil Kumar Sachan, Gaurav Kaithwas, F. A. Al-abbasi, Firoz Anwar and Amita Verma
    Citation: BMC Complementary Medicine and Therapies 2022 22:246
  21. Disseminated intravascular coagulation (DIC) is a syndrome characterized by coagulopathy, microthrombus, and multiple organ failure. The complement system in DIC is overactivated, and the functions of compleme...

    Authors: Qi-Yun Zhang, Jing Guo, Lin Xu, Ying Wei, Shu-Ting Zhou, Qing-Yu Lu, Li Guo and Qian-Yun Sun
    Citation: BMC Complementary Medicine and Therapies 2022 22:245
  22. Traditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treat...

    Authors: Haibo Hu, Yanfang Yang, Abdallah Aissa, Volkan Tekin, Jialin Li, Sujogya Kumar Panda, Hao Huang and Walter Luyten
    Citation: BMC Complementary Medicine and Therapies 2022 22:244
  23. Cardiovascular diseases cause the death of 17.5 million people every year. Cardiac catheterization is an invasive diagnostic exam that allows treatment followed by the examination and can cause some complicati...

    Authors: Kauanny Vitoria Gurgel dos Santos, Karena Cristina da Silva Leal, Louise Constancia de Melo Alves Silva, Kleyton Santos de Medeiros, Alexsandra Rodrigues Feijão, Maria do Carmo de Oliveira, Daniele Vieira Dantas and Rodrigo Assis Neves Dantas
    Citation: BMC Complementary Medicine and Therapies 2022 22:243
  24. Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a health-promoting medicinal food The objective of the present study is to evaluate the anti-as...

    Authors: Kyung Hee Lee, Yeo Jin Jang, Woon Sang Hwang, Ki Sun Kwon, Wha Young Lee, Jeanman Kim, Sung Phil Kim and Mendel Friedman
    Citation: BMC Complementary Medicine and Therapies 2022 22:242
  25. Osteoporosis, a skeletal disease described by impaired bone strength, cause an increased risk of fractures. We aimed in this study to clarify which particular wise combination of probiotics has the most benefi...

    Authors: Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Farhad Koohpeyma, Pedram Talezadeh and Nima Montazeri-Najafabady
    Citation: BMC Complementary Medicine and Therapies 2022 22:241
  26. To curb the spread of the first wave of the COVID-19 pandemic, the Swiss government declared a state of health emergency and ordered a legal restriction concerning the opening of healthcare institutions. In th...

    Authors: Angélique Bourqui, Pierre-Yves Rodondi, Emna El May and Julie Dubois
    Citation: BMC Complementary Medicine and Therapies 2022 22:240
  27. Cervical cancer remains one of the significant causes of mortality in women due to the limitations of current treatment strategies and their associated side effects. Investigation of alternative medicine, incl...

    Authors: Saurav Kumar, Vaishali Mulchandani and Jayasri Das Sarma
    Citation: BMC Complementary Medicine and Therapies 2022 22:239
  28. There is paucity of data regarding effects of guided meditation (Yoganidra) on quality of life among patients of chronic kidney disease on maintenance hemodialysis. Our objective was to study effects of guided...

    Authors: Bhalendu S. Vaishnav, Jekishan Jayeshbhai Hirapara and Maulin K. Shah
    Citation: BMC Complementary Medicine and Therapies 2022 22:238
  29. Canadians seeking medical cannabis (MC) may encounter difficulties in finding a healthcare provider (HCP) who authorizes their access to it. Barriers that HCPs face in authorizing MC are unclear. The objective...

    Authors: Yasmina Hachem, Sara J. Abdallah, Sergio Rueda, Jessica L. Wiese, Kamna Mehra, Jennifer Rup, Juthaporn Cowan, Antonio Vigano and Cecilia T. Costiniuk
    Citation: BMC Complementary Medicine and Therapies 2022 22:237
  30. This article has been retracted. Please see the Retraction Notice for more detail: 10.1186/s12906-015-0733-1

    Authors: Cheng Liu, Xia Yuan, Le Tao, Zhuoan Cheng, Xiuqin Dai, Xia Sheng and Dongying Xue
    Citation: BMC Complementary Medicine and Therapies 2022 22:236
  31. Lysiphyllum strychnifolium (Craib) A. Schmitz, a traditional Thai medicinal plant, is mainly composed of polyphenols and flavonoids and exhibits several pharmacological activities, including antioxidant, anticanc...

    Authors: Kunwadee Noonong, Kanta Pranweerapaiboon, Kulathida Chaithirayanon, Kantamat Surayarn, Phicharinee Ditracha, Narin Changklungmoa, Pornanan Kueakhai, Poonsit Hiransai and Kingkan Bunluepuech
    Citation: BMC Complementary Medicine and Therapies 2022 22:235
  32. The COVID-19 pandemic lockdown has had a profound impact on physical and mental well-being throughout the world. Previous studies have revealed that complementary and alternative medicine (CAM) is frequently u...

    Authors: Agnete Egilsdatter Kristoffersen, Miek C. Jong, Johanna Hök Nordberg, Esther T. van der Werf and Trine Stub
    Citation: BMC Complementary Medicine and Therapies 2022 22:234
  33. The plant-based medicinal food (PBMF) is a functional compound extracted from 6 medicinal and edible plants: Coix seed, L. edodes, A. officinalis L., H. cordata, Dandelion, and G. frondosa. Our previous studies h...

    Authors: Lin Tian, Xuxi Chen, Li Cao, Lishi Zhang and Jinyao Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:233
  34. Chronic ultraviolet (UV) exposure is one of the major external factors in skin aging, and repetitive UVB exposure induces extracellular matrix (ECM) damage as well as metabolic disease. Alpinia officinarum Rhizom...

    Authors: Jong Min Jung, Oh Yun Kwon, Jong Kyu Choi and Seung Ho Lee
    Citation: BMC Complementary Medicine and Therapies 2022 22:232
  35. Epilepsy induces behavioral effects and histological changes in the hippocampus. Eugenol, the main component of clove essential oil, has modulatory effects on seizure. We aimed to investigate the effect of int...

    Authors: Fatemeh Parvizi, Soraya Mehrabi, Ayeh Naghizadeh, Mohammad Kamalinejad‬, Sepide Goudarzi and ‬‬‬‬‬‬‬‬‬‬ Maryam Farahmandfar
    Citation: BMC Complementary Medicine and Therapies 2022 22:231
  36. Authors: León F. Villegas Vílchez, Julio Hidalgo Ascencios and Thomas P. Dooley
    Citation: BMC Complementary Medicine and Therapies 2022 22:230

    The original article was published in BMC Complementary Medicine and Therapies 2022 22:62

  37. The aim of this study is investigate the antimicrobial effect of plant oils against bacterial strains isolated from neonatal asymptomatic bacteriuria (ABU) and to evaluate the antiseptic effect of the most pot...

    Authors: Rasha H. Bassyouni, Zeinat Kamel, Alkassem Ahmed Algameel, Ghada Ismail and Sylvana N. Gaber
    Citation: BMC Complementary Medicine and Therapies 2022 22:229
  38. Honey has broad spectrum antibacterial activity against clinically important organisms and may be suitable for treating superficial bacterial infections. However, very little data are available describing pote...

    Authors: Brayden H. Gray, Kathryn J. Green, Robbie R. Haines and Katherine A. Hammer
    Citation: BMC Complementary Medicine and Therapies 2022 22:228
  39. Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular ...

    Authors: Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani and Gaber El-Saber Batiha
    Citation: BMC Complementary Medicine and Therapies 2022 22:227
  40. Delay in episiotomy wound healing can lead to infection. The application of natural antimicrobial agents isolated from herbal essences can be a good strategy to prevent the growth of bacteria and promote the w...

    Authors: Fatemeh Hadizadeh-Talasaz, Fariba Mardani, Narjes Bahri, Hassan Rakhshandeh, Nasim Khajavian and Marzieh Taghieh
    Citation: BMC Complementary Medicine and Therapies 2022 22:226
  41. Complementary and alternative medicine (CAM) has played a critical role in ensuring universal access to basic health care services around the world. In Bangladesh, conventional medicine is a common approach fo...

    Authors: Md. Shahjalal, Jeff Gow, Md. Ashfikur Rahman, Md. Jakir Hossain, Md. Nafiul Alam Khan, Md. Sazzadul Alam, Ahmed Hossain and Rashidul Alam Mahumud
    Citation: BMC Complementary Medicine and Therapies 2022 22:225
  42. Oxidative stress can induce age-related diseases. Age-related retinal diseases, such as age-related macular degeneration (AMD), are difficult to cure owing to their complicated mechanisms. Although anti-neovas...

    Authors: Yibo Gong, Xuechun Wang, Yuchuan Wang, Peng Hao, Hao Wang, Yatu Guo and Wei Zhang
    Citation: BMC Complementary Medicine and Therapies 2022 22:224
  43. Symphonia globulifera and Allophylus abyssinicus are used in the management of skin rashes and sores, cough, malaria, digestive diseases, stomach ache, wounds and helminthic infections among others in Uganda, Ken...

    Authors: Ben Lukubye, Clement Olusoji Ajayi, Rapheal Wangalwa and Grace Kagoro-Rugunda
    Citation: BMC Complementary Medicine and Therapies 2022 22:223
  44. Morinda citrifolia (Noni) is a plant that has long been used in various products such as foods and cosmetics. Although noni has been known to have immunostimulatory activity, detailed mechanism at the cellular le...

    Authors: Haeyeop Kim, Laily Rahmawati, Yo Han Hong, Su-Young Choi and Jae Youl Cho
    Citation: BMC Complementary Medicine and Therapies 2022 22:222
  45. The leaf of Eucalyptus globulus is commonly used in the traditional management of malaria. However, the efficacy of solvent fractions are didn’t study yet scientifically. Thus, this study aimed to investigate the...

    Authors: Mihret Ayalew, Seyfe Asrade Atnafie and Azmeraw Bekele
    Citation: BMC Complementary Medicine and Therapies 2022 22:221
  46. Zuojin formula, a traditional Chinese medicine, comprises Coptis chinensis and Evodia rutaecarpa. In our previous study, the total alkaloid extract from Zuojin formula (TAZF) showed potent and improved efficacy. ...

    Authors: Shuo Wang, Tao Zhang, Xiaoyan Liu, Zheng Yang, Ludi Li, Danping Shan, Yadong Gao, Yingzi Li, Yanying Li, Youbo Zhang and Qi Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:220
  47. Though there are reports about V. auriculifera antimicrobial activity, there is not enough information about its activity on some bacterial and fungal species. Besides, there was no quantitative evaluation done f...

    Authors: Teshale Etiso Wado, Sultan Suleman and Tesfaye Mohammed
    Citation: BMC Complementary Medicine and Therapies 2022 22:219
  48. Globally, the usage of herbal medicines (HMs) is increasingly growing in treating and preventing various ailments. Although, HMs play a vital role in healthcare, concerns have been raised over their safety. Si...

    Authors: Alemseghed Goitom, Feruz Yemane, Mussie Tsegay, Amanuel Kifleyesus, Senai Mihreteab Siele, Eyasu H. Tesfamariam and Nuru Abdu
    Citation: BMC Complementary Medicine and Therapies 2022 22:218
  49. Prasachandaeng (PSD) remedy has been empirically used in Thai traditional medicine to treat fever in bile duct and liver and cancer patients through Thai folk doctors. However, there have been no scientific re...

    Authors: Nuntika Prommee, Arunporn Itharat, Pakakrong Thongdeeying, Sunita Makchuchit, Weerachai Pipatrattanaseree, Adis Tasanarong, Buncha Ooraikul and Neal M. Davies
    Citation: BMC Complementary Medicine and Therapies 2022 22:217
  50. The traditional Chinese medicine (TCM) formula 01 for nasopharyngeal carcinoma (NPC01) is used in the management of head and neck cancers (HNCs), but whether NPC01 has an impact on the HR-QOL of patients with ...

    Authors: Li Yanwei, He Feng, Wang Xudong and Pan Zhanyu
    Citation: BMC Complementary Medicine and Therapies 2022 22:216