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  1. Complementary and alternative medicine (CAM) use among infertile women is popular in many countries, including Korea. Previous research has repeatedly found more than half of infertile women surveyed use CAM t...

    Authors: Jung Hye Hwang, Yi Young Kim, Hyea Bin Im and Dongwoon Han

    Citation: BMC Complementary and Alternative Medicine 2019 19:301

    Content type: Research article

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  2. Obesity and dyslipidemia are major risk factors associated with non-alcoholic fatty liver disease (NAFLD). NAFLD refers to the accumulation of fat in more than 5% of the liver without alcohol consumption. NAFL...

    Authors: Chattraya Ngamlerst, Arunwan Udomkasemsab, Ratchanee Kongkachuichai, Karunee Kwanbunjan, Chaowanee Chupeerach and Pattaneeya Prangthip

    Citation: BMC Complementary and Alternative Medicine 2019 19:294

    Content type: Research article

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  3. Numerous health benefits have been demonstrated for curcumin which is extracted from turmeric (Curcuma longa L). However, due to its poor absorption in the free form in the gastrointestinal tract and rapid biotra...

    Authors: Sidney J. Stohs, C. Y. O. Chen, Harry G. Preuss, Sidhartha D. Ray, Luke R. Bucci, Jin Ji and Kevin J. Ruff

    Citation: BMC Complementary and Alternative Medicine 2019 19:293

    Content type: Research article

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  4. The herbal medicine Bryophyllum pinnatum has been used as a tocolytic agent in anthroposophic medicine and, recently, in conventional settings alone or as an add-on medication with tocolytic agents such as atosib...

    Authors: S. Santos, C. Haslinger, M. Mennet, U. von Mandach, M. Hamburger and A. P. Simões-Wüst

    Citation: BMC Complementary and Alternative Medicine 2019 19:292

    Content type: Research article

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  5. Vaccinium oldhamii (V. oldhamii) has been reported to exert a variety of the pharmacological properties such as anti-oxidant activity, anti-cancer activity, and inhibitory activity of α-amylase and acetylcholines...

    Authors: Ha Na Kim, Jueng Kyu Baek, Su Bin Park, Jeong Dong Kim, Ho-Jun Son, Gwang Hun Park, Hyun Ji Eo, Jae Ho Park, Hyuk-Sang Jung and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2019 19:291

    Content type: Research article

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  6. Nigella sativa or commonly known as black seed or black cumin is one of the most ubiquitous complementary medicine. Epithelial to mesenchymal transition (EMT) of type 2 is defined by the balance between wound hea...

    Authors: Abid Nordin, Haziq Kamal, Muhammad Dain Yazid, Aminuddin Saim and Ruszymah Idrus

    Citation: BMC Complementary and Alternative Medicine 2019 19:290

    Content type: Research article

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  7. Natural extracts with beneficial biological activities are nowadays of high interest, in various treatment or prophylaxis. Hypericum capitatum has been known for its curative effects for centuries and its extract...

    Authors: Anca D. Farcas, Augustin C. Mot, Cezara Zagrean-Tuza, Madalina Ticolea, Bogdan Sevastre, Muhittin Kulak, Radu Silaghi-Dumitrescu and Alina Parvu

    Citation: BMC Complementary and Alternative Medicine 2019 19:289

    Content type: Research article

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  8. Extracts from medicinal plants with phytochemicals with known antimicrobial properties can be an effective adjunct in the complex treatment of infectious diseases. This study aimed to evaluate the antimicrobia...

    Authors: Aliya S. Mamatova, Izabela Korona-Glowniak, Krystyna Skalicka-Woźniak, Aleksandra Józefczyk, Krzysztof K. Wojtanowski, Tomasz Baj, Zuriyadda B. Sakipova and Anna Malm

    Citation: BMC Complementary and Alternative Medicine 2019 19:288

    Content type: Research article

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  9. Sarcopenia, the decline of skeletal muscle tissue attributed to primary aging is a major concern in older adults. Flavonoids might have potential benefits by modulating the regulation of satellite cells, thus ...

    Authors: Jin-A Kim, Seong Min Kim, Sang Eun Ha, Preethi Vetrivel, Venu Venkatarame Gowda Saralamma, Eun Hee Kim and Gon Sup Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:287

    Content type: Research article

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  10. Edible insects, including Oxya chinensis sinuosa Mishchenko (Oc), which is consumed as food in Asia, are considered as a human food shortage alternative, and also as a preventive measure against environmental des...

    Authors: A-Rang Im, InWha Park, Kon-Young Ji, Joo Young Lee, Ki Mo Kim, MinKyun Na and Sungwook Chae

    Citation: BMC Complementary and Alternative Medicine 2019 19:286

    Content type: Research article

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  11. Electroacupuncture (EA) is often used in clinical settings due to its analgesic effect, but its safety has not been verified due to the lack of clear criteria. This study examined the critical range of the cor...

    Authors: Kwang-Ho Choi, Sun Hee Yeon, Seong Jin Cho, O Sang Kwon, Sanghun Lee, Su Yeon Seo, Suk-Yun Kang and Yeonhee Ryu

    Citation: BMC Complementary and Alternative Medicine 2019 19:285

    Content type: Research article

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  12. Stem bark of Luehea ochrophylla (L. ochrophylla) is used by the traditional Brazilian medicine for treatment of rheumatic diseases and tumors. This study aimed to investigate inhibition of acute and chronic infla...

    Authors: Clináscia Rodrigues Rocha Araújo, Thiago de Melo Silva, Michaelle Geralda dos Santos, Marcelo Henrique Fernandes Ottoni, Elaine Maria de Souza Fagundes, Humberto de Sousa Fontoura, Gustavo Eustáquio Brito Alvim de Melo and Antônio Flávio de Carvalho Alcântara

    Citation: BMC Complementary and Alternative Medicine 2019 19:284

    Content type: Research article

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  13. A potato protein hydrolysate, APPH is a potential anti-obesity diet ingredient. Since, obesity leads to deterioration of liver function and associated liver diseases, in this study the effect of APPH on high f...

    Authors: Shibu Marthandam Asokan, Tsu-Han Hung, Zong-Yan Li, Wen-Dee Chiang and Wan-Teng Lin

    Citation: BMC Complementary and Alternative Medicine 2019 19:283

    Content type: Research article

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  14. Aim of this study was to evaluate the effectiveness of scalp, tongue, and Jin’s 3-needle acupuncture for the improvement of postapoplectic aphasia.

    Authors: He-yong Tang, Wei Tang, Feng Yang, Wei-wei Wu and Guo-ming Shen

    Citation: BMC Complementary and Alternative Medicine 2019 19:282

    Content type: Research article

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  15. Cedrus deodara (Roxb.) Loud (normally called as deodar), one out of four species in the genus Cedrus, exhibits widely biological activities. The Cedrus deodara total lignans from the pine needles (CTL) were extra...

    Authors: Xiaofeng Shi, Ruiqin Du, Junmin Zhang, Yanping Lei and Hongyun Guo

    Citation: BMC Complementary and Alternative Medicine 2019 19:281

    Content type: Research article

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  16. Peritoneal fibrosis (PF) remains a serious complication of long-term peritoneal dialysis (PD). The goal of this study was to investigate the anti-fibrotic effects of curcumin on the PF response to PD and its’ ...

    Authors: Jun-Li Zhao, Ting Zhang, Xia Shao, Jun-Jun Zhu and Mei-Zi Guo

    Citation: BMC Complementary and Alternative Medicine 2019 19:280

    Content type: Research article

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  17. Rapid emergence of multidrug resistant (MDR) organisms in hospital and community settings often result into treatment failure, thus leading the clinicians with fewer treatment options. Cyathea gigantea, an ethnom...

    Authors: Kathakali Nath, Anupam Das Talukdar, Mrinal Kanti Bhattacharya, Deepshikha Bhowmik, Shiela Chetri, Debarati Choudhury, Abhijit Mitra and Nargis Alom Choudhury

    Citation: BMC Complementary and Alternative Medicine 2019 19:279

    Content type: Research article

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  18. Recent epidemiological and experimental studies suggest that cadmium and diabetes-related hyperglycemia may act synergistically to worsen metabolic regulation. The present study aims to evaluate the potential ...

    Authors: Mohammad Nazmul Hasan, Farah Sabrin, Begum Rokeya, Md Shahinul Haque Khan, Mahtab Uddin Ahmed, Abel Matondo, Md Morsaline Billah and Salima Akter

    Citation: BMC Complementary and Alternative Medicine 2019 19:278

    Content type: Research article

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  19. Clinical Practice Guidelines (CPGs) play an important role in clinical practice, and they require appropriate evaluation, especially in application. This study explores the application evaluation method of CPG...

    Authors: Huayang Cai, Hui Li, Huizhen Zeng, Danping Xu, Wenwei Ouyang and Aiping Lv

    Citation: BMC Complementary and Alternative Medicine 2019 19:277

    Content type: Research article

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  20. Lead, mercury, cadmium, chromium, and arsenic intoxication have been associated with the use of health supplement (HS) products. The aim of this study is to estimate the concentration of heavy metals in HS pro...

    Authors: Naseem Mohammed Abdulla, Balazs Adam, Iain Blair and Abderrahim Oulhaj

    Citation: BMC Complementary and Alternative Medicine 2019 19:276

    Content type: Research article

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  21. Pyrola decorata H. Andres, is exclusively distributed in China and a source of traditional Chinese herbal medicine Luxiancao for more than 2000 years. Here, we evaluated the antioxidant and cytoprotective effects...

    Authors: Ban Chen, Xican Li, Jie Liu, Wei Qin, Minshi Liang, Qianru Liu and Dongfeng Chen

    Citation: BMC Complementary and Alternative Medicine 2019 19:275

    Content type: Research article

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  22. Recent research has suggested that autophagy can provide a better mechanism for inducing cell death than current therapeutic strategies. This study investigated the effects of using an ethanol extract of Chrys...

    Authors: Kwang-Youn Kim, Tae-Woo Oh, Hye-Jin Yang, Young-Woo Kim, Jin-Yeul Ma and Kwang-Il Park

    Citation: BMC Complementary and Alternative Medicine 2019 19:274

    Content type: Research article

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  23. Curcumin is known for its multitude of medicinal properties, including anti-cancer and migrastatic activity. Efforts to overcome poor bioavailability, stability, and side effects associated with the higher dos...

    Authors: Jinsha Koroth, Snehal Nirgude, Shweta Tiwari, Vidya Gopalakrishnan, Raghunandan Mahadeva, Sujeet Kumar, Subhas S. Karki and Bibha Choudhary

    Citation: BMC Complementary and Alternative Medicine 2019 19:273

    Content type: Research article

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  24. This study aimed to investigate the effect of the Phellinus linteus (Mesima) decoction on podocyte injury in a rat model of focal and segmental glomerulosclerosis (FSGS) and evaluate the potential mechanisms.

    Authors: Feng Wan, Ru-chun Yang, Yan-peng Shi, Yue-Wen Tang, Xuan-li Tang, Xiao-ling Zhu, You-gui Li and Yong-jun Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:272

    Content type: Research article

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  25. Plant secondary metabolites and phytochemicals that exhibit strong bioactivities have potential to be developed as safe and efficient natural antimicrobials against food contamination and addressing antimicrob...

    Authors: Dan Zhou, Ze-Hua Liu, Dong-Mei Wang, Deng-Wu Li, Li-Na Yang and Wei Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:271

    Content type: Research article

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  26. Benign prostatic hyperplasia (BPH) is a pathological condition affecting older men. BPH complications often lead to deterioration in the quality of life. Serenoa repens (Saw Palmetto) is used for treating lower u...

    Authors: Heggar V. Sudeep, Karempudi Venkatakrishna, Ballal Amrutharaj, Anitha and Kodimule Shyamprasad

    Citation: BMC Complementary and Alternative Medicine 2019 19:270

    Content type: Research article

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  27. Puerarin exerts therapeutic effect on osteoporosis due to its inhibitory effect on the formation of osteoclasts. Puerarin is also widely established as an autophagy inhibitor. The study aimed to investigate th...

    Authors: Guoyou Zhang, Yu Wang, Guoke Tang and Yuanzheng Ma

    Citation: BMC Complementary and Alternative Medicine 2019 19:269

    Content type: Research article

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  28. Long-term use of most immunosuppressants to treat allergic contact dermatitis (ACD) generates unavoidable severe side effects, warranting discovery or development of new immunosuppressants with good efficacy a...

    Authors: Premrutai Thitilertdecha, Panwadee Pluangnooch, Sunita Timalsena and Kitipong Soontrapa

    Citation: BMC Complementary and Alternative Medicine 2019 19:268

    Content type: Research article

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  29. Cancer cachexia is a cancer-induced multifactorial debilitating syndrome directly accounting for 20% of cancer deaths without effective therapeutic approaches. It is extremely urgent to explore effective anti-...

    Authors: Huiquan Liu, Lu Li, Jun Zou, Ting Zhou, Bangyan Wang, Huihui Sun and Shiying Yu

    Citation: BMC Complementary and Alternative Medicine 2019 19:267

    Content type: Research article

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  30. Propolis is a natural bee product with a wide range of biological activities that are related to its chemical composition. The present study investigated the quantification of quercetin (Q) in Ardabil ethanol ...

    Authors: Fariba Asgharpour, Ali Akbar Moghadamnia, Ebrahim Zabihi, Sohrab Kazemi, Amirmorteza Ebrahimzadeh Namvar, Hemmat Gholinia, Mina Motallebnejad and Hamid Reza Nouri

    Citation: BMC Complementary and Alternative Medicine 2019 19:266

    Content type: Research article

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  31. Carica papaya (CP) extract is becoming popular as an unlicensed herbal remedy purported to hasten recovery in dengue infection, mostly based on observations that it may increase platelet counts. This systematic r...

    Authors: Senaka Rajapakse, Nipun Lakshitha de Silva, Praveen Weeratunga, Chaturaka Rodrigo, Chathurani Sigera and Sumadhya Deepika Fernando

    Citation: BMC Complementary and Alternative Medicine 2019 19:265

    Content type: Research article

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  32. Osteoarthritis (OA) is a common degenerative disease of synovial joints caused by inflammation. Acteoside (ACT), a major component and lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha, has b...

    Authors: Zhiguang Qiao, Jiaxin Tang, Wen Wu, Jian Tang and Ming Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:264

    Content type: Research article

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  33. Inflammation is a symptom associated with many diseases. This symptom is treated with steroidal and non-steroidal anti-inflammatory drugs, which can cause severe side effects when used as long-term treatments....

    Authors: Axel Villagómez-Rodríguez, Julia Pérez-Ramos, Ana Laura Esquivel-Campos, Cuauhtémoc Pérez-González, Claudia Angélica Soto-Peredo and Salud Pérez-Gutiérrez

    Citation: BMC Complementary and Alternative Medicine 2019 19:263

    Content type: Research article

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  34. Natural products play a significant role in human health in relation to the prevention and treatment of inflammatory conditions. One of the plants with great medicinal potentials is Diospyros kaki which is mainly...

    Authors: Jieun Choi, Mi Jeong Kim, Richard Komakech, Haiyoung Jung and Youngmin Kang

    Citation: BMC Complementary and Alternative Medicine 2019 19:262

    Content type: Research article

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  35. Our previous study exhibited free radicals scavenging and antioxidant activities of ethanolic and aqueous extracts of Tamarindus indica L. leaves in chronic sodium fluoride poisoning in rats. Tamarindus indica L....

    Authors: Bishnu Prasad Sinha, Souvick Chatterjee, Rinku Buragohain, Indranil Samanta, Siddhartha Narayan Joardar, Prasenjit Mukherjee, Asit Kumar Maji, Partha Das, Tapan Kumar Mandal and Tapas Kumar Sar

    Citation: BMC Complementary and Alternative Medicine 2019 19:261

    Content type: Research article

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  36. Dengue is a mosquito-borne viral infection that has become a major public health concern worldwide. Presently, there is no specific vaccine or treatment available for dengue viral infection.

    Authors: Kavithambigai Ellan, Ravindran Thayan, Jegadeesh Raman, Kazuya I. P. J. Hidari, Norizah Ismail and Vikineswary Sabaratnam

    Citation: BMC Complementary and Alternative Medicine 2019 19:260

    Content type: Research article

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  37. Traditional and complementary medicines (T&CM) are any form of medicine, practice, treatment, product, technology, knowledge system or ceremony outside of conventional medical practice that aims to prevent and...

    Authors: A. Gall, K. Anderson, J. Adams, V. Matthews and G. Garvey

    Citation: BMC Complementary and Alternative Medicine 2019 19:259

    Content type: Research article

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  38. Herbal and traditional medicines (HTM) are widely used in Asian countries. Specific data on prevalent of HTM usage and association with chronic diseases in the Thai population is currently lacking. We examined...

    Authors: Napatt Kanjanahattakij, Pakakrong Kwankhao, Prin Vathesatogkit, Nisakron Thongmung, Yingampa Gleebbua, Piyamitr Sritara and Chagriya Kitiyakara

    Citation: BMC Complementary and Alternative Medicine 2019 19:258

    Content type: Research article

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  39. Clinacanthus nutans extracts have been consumed by the cancer patients with the hope that the extracts can kill cancers more effectively than conventional chemotherapies. Our previous study reported its anti-infl...

    Authors: Ling-Wei Hii, Swee-Hua Erin Lim, Chee-Onn Leong, Swee-Yee Chin, Ngai-Paing Tan, Kok-Song Lai and Chun-Wai Mai

    Citation: BMC Complementary and Alternative Medicine 2019 19:257

    Content type: Research article

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  40. Arisaema jacquemontii is traditionally used in treatment of different diseases. In this study, phytochemical, in vitro biological and chemo-preventive screening of A. jacquemontii was carried out to explore its p...

    Authors: Saira Tabassum, Muhammad Zia, Esperanza J. Carcahe de Blanco, Riffat Batool, Roohi Aslam, Sajid Hussain, Qamar Wali and Muhammad Mudassar Gulzar

    Citation: BMC Complementary and Alternative Medicine 2019 19:256

    Content type: Research article

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  41. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initi...

    Authors: Ke Fang, Fan Wu, Guang Chen, Hui Dong, Jingbin Li, Yan Zhao, Lijun Xu, Xin Zou and Fuer Lu

    Citation: BMC Complementary and Alternative Medicine 2019 19:255

    Content type: Research article

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  42. Fumaria species (Fumariacea) has traditionally been used in wound healing in Iranian folk medicine. However, with the discovery of newer agents, its use has faded off into total obscurity. This study explored the...

    Authors: Fatemeh Davoodi-Roodbordeii, Minoo Afshar, Fatemeh Haji Abas Tabrizi, Samira Choopani, Giti Torkaman, Fariborz Moayer and Mona Salimi

    Citation: BMC Complementary and Alternative Medicine 2019 19:254

    Content type: Research article

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  43. General antiviral agents such as oseltamivir are associated with certain adverse effects and the emergence of resistance. This study investigated the phytochemical properties, antiviral activities, and safety ...

    Authors: Won-Young Bae, Hyeong-Yeop Kim, Kyoung-Sook Choi, Kyung Hoon Chang, Young-Ho Hong, Jongsu Eun, Na-Kyoung Lee and Hyun-Dong Paik

    Citation: BMC Complementary and Alternative Medicine 2019 19:253

    Content type: Research article

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  44. Turmeric is commonly used as a dietary treatment for inflammation, but few studies have evaluated the direct effect of turmeric on cartilage. The purpose of this study was to characterize cartilage explants’ i...

    Authors: Wendy Pearson and Laima S. Kott

    Citation: BMC Complementary and Alternative Medicine 2019 19:252

    Content type: Research article

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  45. While traditional, complementary and alternative medicine (TCAM) is gaining increased interest worldwide, the structural factors associated with the usage of TCAM at the social level have not been sufficiently...

    Authors: Jimpei Misawa, Rie Ichikawa, Akiko Shibuya, Yukihiro Maeda, Ichiro Arai, Teruyoshi Hishiki and Yoshiaki Kondo

    Citation: BMC Complementary and Alternative Medicine 2019 19:251

    Content type: Research article

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  46. Parents’ use of complementary health approaches (CHA) for children with autism spectrum disorder (ASD) are common despite the uncertain evidence of its benefit. Parents often adopt CHA due to dissatisfaction w...

    Authors: Jun Jean Ong

    Citation: BMC Complementary and Alternative Medicine 2019 19:250

    Content type: Research article

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  47. Bacteria have developed resistance to most of the current antibiotics. There is evidence suggesting that plant-derived compounds have a potential for interacting with biological processes. One of the plants co...

    Authors: Winnie Mozirandi, Dexter Tagwireyi and Stanley Mukanganyama

    Citation: BMC Complementary and Alternative Medicine 2019 19:249

    Content type: Research article

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  49. Cosmos caudatus is an annual plant known for its medicinal value in treating several health conditions, such as high blood pressure, arthritis, and diabetes mellitus. The α-glucosidase inhibitory activity and tot...

    Authors: Wan Ahmad Wan-Nadilah, Muhammad Tayyab Akhtar, Khozirah Shaari, Alfi Khatib, Azizah Abdul Hamid and Muhajir Hamid

    Citation: BMC Complementary and Alternative Medicine 2019 19:245

    Content type: Research article

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  50. Brown adipocytes are known to promote energy expenditure and limit weight gain to combat obesity. Averrhoa bilimbi, locally called belimbing buluh (DBB), is mainly used as an ethnomedicine in the treatment of met...

    Authors: Wai Kwan Lau, Nur Adelina Ahmad Noruddin, Abdul Hadi Ariffin, Muhd Zulkarnain Mahmud, Mohd Hasnan Mohd Noor, Azimah Amanah, Mohamad Faiz Hamzah and Zainuddin Zafarina

    Citation: BMC Complementary and Alternative Medicine 2019 19:243

    Content type: Research article

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