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  1. Ginseng (Panax ginseng C.A. Mey.) has been used as a valuable ingredient in traditional medicine for thousands of years mostly in Asian countries due to its therapeutic effects in various diseases. Among the proc...

    Authors: Jin-Sung Park, Seung-Hyun Kim, Kang-Min Han, Yun-Soon Kim, Euna Kwon, Se-Hee Paek, Yong-Ki Seo, Jun-Won Yun and Byeong-Cheol Kang
    Citation: BMC Complementary Medicine and Therapies 2022 22:44
    Content type: Research Published on:

  2. Major life changing events such as the COVID-19 pandemic may have major impact on one’s health and general well-being. This study aimed to determine the prevalence and predictive factors, including gender spec...

    Authors: Louise T. C. Mulder, Martine Busch, Agnete E. Kristoffersen, Johanna Hök Nordberg and Esther T. van der Werf
    Citation: BMC Complementary Medicine and Therapies 2022 22:43
    Content type: Research Published on:

  3. Antibiotic resistances of pathogens and breast cancer warrant the search for new alternative strategies. Phytoextracts can eradicate microbe-borne diseases as well as cancer with lower side effects compared to...

    Authors: Kartik Chandra Guchhait, Tuhin Manna, Manas Barai, Monalisha Karmakar, Sourav Kumar Nandi, Debarati Jana, Aditi Dey, Suman Panda, Priyanka Raul, Anuttam Patra, Rittwika Bhattacharya, Subhrangsu Chatterjee, Amiya Kumar Panda and Chandradipa Ghosh
    Citation: BMC Complementary Medicine and Therapies 2022 22:42
    Content type: Research Published on:

  4. Stroke is the second most common cause of death worldwide. Even after surviving, long-term rehabilitation often becomes necessary and does not always lead to complete recovery. Guidelines focus on prevention o...

    Authors: Wiebke K. Kohl-Heckl, Anna K. Koch and Holger Cramer
    Citation: BMC Complementary Medicine and Therapies 2022 22:41
    Content type: Research Published on:

  5. Parkinson’s disease (PD) is a multifactorial movement disorder with the progressive degeneration of the nigrostriatal system that impairs patients’ movement ability. Oxidative stress has been found to affect t...

    Authors: Saeideh Nourmohammadi, Sanaz Yousefi, Mahboubeh Manouchehrabadi, Mona Farhadi, Zahra Azizi and Anahita Torkaman-Boutorabi
    Citation: BMC Complementary Medicine and Therapies 2022 22:40
    Content type: Research Published on:

  6. Recurrence and resistance of Candida spp. infections is associated with the ability of these microorganisms to present several virulence patterns such as morphogenesis, adhesion, and biofilm formation. In the sea...

    Authors: Camila Cid-Chevecich, Andrea Müller-Sepúlveda, José Antonio Jara, Rodrigo López-Muñoz, Rocío Santander, Mauricio Budini, Alejandro Escobar, Raúl Quijada, Alfredo Criollo, Mario Díaz-Dosque and Alfredo Molina-Berríos
    Citation: BMC Complementary Medicine and Therapies 2022 22:39
    Content type: Research Published on:

  7. Intestinal epithelial barrier dysfunction predisposes to many gastrointestinal, metabolic, and psychological disorders. A flavonoid rich extract of Glycyrrhiza glabra (FREG) has previously been reported to posses...

    Authors: Sasi Kumar Murugan, Bharathi Bethapudi, Subramanian Raghunandhakumar, Divya Purusothaman, Muruganantham Nithyanantham, Deepak Mundkinajeddu and Muralidhar Srinivasaih Talkad
    Citation: BMC Complementary Medicine and Therapies 2022 22:38
    Content type: Research Published on:

  8. Patients with long-term neurological conditions, such as Parkinson’s disease (PD), are particularly vulnerable to the public health measures taken to combat the COVID-19 pandemic. The inaccessibility of center...

    Authors: Jojo Yan Yan Kwok, Jung Jae Lee, Edmond Pui Hang Choi, Pui Hing Chau and Man Auyeung
    Citation: BMC Complementary Medicine and Therapies 2022 22:37
    Content type: Research Published on:

  9. Abelmoschus manihot (L.) Medicus (AM) is a medicinal plant with various biological activities, including anti-inflammatory, antioxidant, antiviral and immunomodulatory. Previous studies have identified total flav...

    Authors: Yanan Gao, Zihao Liang, Nianyin Lv, Jinjun Shan, Huihui Zhou, Junfeng Zhang and Liyun Shi
    Citation: BMC Complementary Medicine and Therapies 2022 22:36
    Content type: Research Published on:

  10. The chemokine CXCL12 and its two receptors (CXCR4 and CXCR7) are involved in inflammation and hematopoietic cell trafficking. This study was designed to investigate molecular docking interactions of four popul...

    Authors: Hussam Aly Sayed Murad, Thamer Mohammed Ahmed Alqurashi and Mostafa Aly Hussien
    Citation: BMC Complementary Medicine and Therapies 2022 22:35
    Content type: Research Published on:

  11. We have previously reported that the free fatty acid extract (FFAE) of krill oil (KO) significantly inhibits the proliferation and migration, and induces apoptosis of colorectal cancer (CRC) cells. This study ...

    Authors: Abilasha Gayani Jayathilake, Elif Kadife, Nyanbol Kuol, Rodney Brain Luwor, Kulmira Nurgali and Xiao Qun Su
    Citation: BMC Complementary Medicine and Therapies 2022 22:34
    Content type: Research Published on:

  12. Shenzhi Jiannao (SZJN) prescription is a type of herbal formula adopted in the management of cognitive impairment and related disorders. However, its effects and related regulatory mechanisms on vascular demen...

    Authors: Danfeng Tian, Qiang Gao, Ze Chang, Jingfeng Lin, Dayong Ma and Zhenyun Han
    Citation: BMC Complementary Medicine and Therapies 2022 22:33
    Content type: Research article Published on:

  13. The incidence rate of invasive candidiasis is high, its treatment is difficult, and the prognosis is poor. In this study, an immunosuppressive mouse model of invasive Candida albicans (C. albicans) infection was ...

    Authors: Jie-Hua Deng, Xiao-Guang Zhang, Gang-Sheng Wang, Jing-Na Luo, Jia Wang, Xiao-Ming Qi and Yan-Ling Li
    Citation: BMC Complementary Medicine and Therapies 2022 22:32
    Content type: Research article Published on:

  14. Sedum emarginatum Migo(S. emarginatum) has anti-tumor and anti-oxidant effects. This study aimed to screen the extractions of S. emarginatum against liver cancer in vitro and explore its anti-liver cancer mechani...

    Authors: Qin Qiu, Lujuan Jiang, Hanshen Zhen, Fengyin Huang, Dandan Zhen, Meifang Ye, Xueyan Meng, Yuanyuan Liu and Xijun Qin
    Citation: BMC Complementary Medicine and Therapies 2022 22:31
    Content type: Research Published on:

  16. At present, oral antidepressants are commonly used in the clinical treatment of depression. However, the current drug treatment may lead to more serious adverse reactions. Therefore, we focus on Chinese tradit...

    Authors: Xi Chen, Ting Yang, Congen Zhang and Zhijie Ma
    Citation: BMC Complementary Medicine and Therapies 2022 22:29
    Content type: Research Published on:

  17. Acupuncture therapy has been widely used as an alternative therapy to treat multiple diseases, such as sequelae of stroke, pain, facial paralysis and so on. In recent years, few adverse events related to acupu...

    Authors: Xiaochan Tan, Wei Liu, Yuzheng Du, Xianggang Meng and Xuemin Shi
    Citation: BMC Complementary Medicine and Therapies 2022 22:28
    Content type: Case report Published on:

  18. The overuse of antibiotics has led to increased antimicrobial resistance, but plant-derived biological response modifiers represent a potential alternative to these drugs. This investigation examined the immun...

    Authors: Haroon Iqbal, Claire L. Wright, Sue Jones, Goncalo Rosas da Silva, John McKillen, Brendan F. Gilmore, Owen Kavanagh and Brian D. Green
    Citation: BMC Complementary Medicine and Therapies 2022 22:27
    Content type: Research Published on:

  19. Natural phenolic compounds and Phenolics-rich medicinal plants are also of great interest in the management of diabetes. The current study was aimed to analyze phenolics in P. hydropiepr L extracts via HPLC-DAD a...

    Authors: Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Sultan A. Alqahl, Farhat Ullah, Abdul Sadiq, Alam Zeb, Mehreen Ghufran, Alexey Kuraev, Asif Nawaz and Muhammad Ayaz
    Citation: BMC Complementary Medicine and Therapies 2022 22:26
    Content type: Research Published on:

  20. Osteoarthritis (OA) treatment aims to improve inflammation and delay cartilage degeneration. However, there is no effective strategy presently available. Ononin, a representative isoflavone glycoside component...

    Authors: Fang Xu, Liang-Jun Zhao, Ting Liao, Zhao-Cong Li, Lei-Lei Wang, Pan-Yu Lin, Rui Jiang and Qing-Jun Wei
    Citation: BMC Complementary Medicine and Therapies 2022 22:25
    Content type: Research Published on:

  21. Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder diagnosed during adolescence and adulthood. Assessment of the long-term risks of the current drugs for ADHD treatment has been i...

    Authors: Kairui Tang, Wenzhi Hao, Xiaowei Mo, Yueyue Chen, Xiaofang Guo, Liangliang He, Binghua Wang, Juxian Wang, Qingyu Ma, Lijuan Deng and Jiaxu Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:24
    Content type: Research Published on:

  22. Traditional plant-based remedies prescribed to treat diabetes have shown promise in research-based setting. Current research was conducted to examine the antidiabetic and antioxidant effects of methanolic extr...

    Authors: Imtiaz Mustafa, Haseeb Anwar, Shahzad Irfan, Humaira Muzaffar and Muhammad Umar Ijaz
    Citation: BMC Complementary Medicine and Therapies 2022 22:23
    Content type: Research Published on:

  23. To evaluate veteran patient and provider perceptions and preferences on complementary and integrative medicine (CIM) for headache management.

    Authors: Deena E. Kuruvilla, Hayley Lindsey, Amy S. Grinberg, Roberta E. Goldman, Samantha Riley, Sean Baird, Brenda T. Fenton, Jason J. Sico and Teresa M. Damush
    Citation: BMC Complementary Medicine and Therapies 2022 22:22
    Content type: Research Published on:

  25. Osbeckia octandra is a plant endemic to Sri Lanka and is used in ethnomedicine for treating various diseases. However, the anti-cancer properties of O. octandra are yet to be fully investigated. In the present s...

    Authors: Jue Young Kim, Jin Kim, B. M. Ratnayake Bandara, Wanninayake M. Tilakaratne and Dokyeong Kim
    Citation: BMC Complementary Medicine and Therapies 2022 22:20
    Content type: Research Published on:

  26. Vitamin D has an established role in female reproduction. There is also evidence for an association between vitamin D levels and menstrual problems such as premenstrual syndrome (PMS) and dysmenorrhea. Curcumi...

    Authors: Leyla Arabnezhad, Mahtab Mohammadifard, Ladan Rahmani, Zahra Majidi, Gordon A. Ferns and Afsane Bahrami
    Citation: BMC Complementary Medicine and Therapies 2022 22:19
    Content type: Research Published on:

  27. Breast Cancer (BC) is the most common cancer in women worldwide and, although 70% of patients are responsive to selective Estrogen Receptor (ER) modulators such as Tamoxifen (Tam), patients’ survival is compri...

    Authors: Douglas C. Brandão, Paula M. A. P. Lima, Isabella C. Martins, Carina S. Cordeiro, Antonielle O. Cordeiro, Lara Vecchi, Joyce F. C. Guerra, Priscila C. Orsolin, Matheus C. Gazolla, Danilo S. Costa, Ademar A. da Silva Filho and Thaise G. Araújo
    Citation: BMC Complementary Medicine and Therapies 2022 22:18
    Content type: Research Published on:

  28. Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease with scantly effective treatment. Numerous evidences indicated that macrophages play an important role in the occurrence and patho...

    Authors: Xiao Lin, Xiao-qin Lei, Jie-ke Yang, Jian Jia, Xia Zhong, Rui-zhi Tan and Li Wang
    Citation: BMC Complementary Medicine and Therapies 2022 22:17
    Content type: Research Published on:

  29. Several local communities in Central, Western, Eastern, and Northern regions of Uganda have been using the whole leaf extracts of Aloe vera (L.) Burm. f. (Asphodelaceae) in the treatment of various ailments. Also...

    Authors: Florence Nalimu, Joseph Oloro, Emanuel L. Peter and Patrick Engeu Ogwang
    Citation: BMC Complementary Medicine and Therapies 2022 22:16
    Content type: Research Published on:

  30. High glucose concentration increases the glycation process which leads to oxidative stress and inflammation, that can cause complications in diabetes. Several medicinal plants have been used in the treatment o...

    Authors: Evy Yulianti, Sunarti and Mae Sri Hartati Wahyuningsih
    Citation: BMC Complementary Medicine and Therapies 2022 22:15
    Content type: Research article Published on:

  31. Traditional and Complementary Medicine (TCM) is widely used particularly among patients with chronic diseases in primary care. However, evidence is lacking regarding TCM use among patients with Metabolic Syndr...

    Authors: Nor Farha Basri, Anis Safura Ramli, Mariam Mohamad and Khairatul Nainey Kamaruddin
    Citation: BMC Complementary Medicine and Therapies 2022 22:14
    Content type: Research Published on:

  32. P-glycoprotein (P-gp)-mediated steroid resistance (SR) has been suggested to play a significant role in lupus nephritis (LN) treatment failure. Panax notoginseng saponins (PNS), the main effective components o...

    Authors: Feng Pan, Yue-jin Li and Ying Lu
    Citation: BMC Complementary Medicine and Therapies 2022 22:13
    Content type: Research article Published on:

  33. Rubus occidentalis, also known as black raspberry, contains several bioactive components that vary depending on the maturity of the fruit. The goal of this study was to evaluate the efficacy of immature Rubus oc...

    Authors: Geun Joo Choi, Hyun Kang, Oh Haeng Lee, Eun Jin Ahn, Fletcher A. White, Ye Jin Cho, Chong Wha Baek, Yong Hun Jung and Ji Wung Kwon
    Citation: BMC Complementary Medicine and Therapies 2022 22:12
    Content type: Research article Published on:

  34. Cerebral malaria is one of the most severe complications attributed to protozoal infection by Plasmodium falciparum, gaining prominence in children mortality rates in endemic areas. This condition has a complex p...

    Authors: Karen Renata Herculano Matos Oliveira, Marjorie Lujan Marques Torres, Nayara Kauffmann, Brenda Jaqueline de Azevedo Ataíde, Nívia de Souza Franco Mendes, Larissa Medeiros dos Anjos, Rosivaldo dos Santos Borges, Carlomagno Pacheco Bahia, Luana Ketlen Reis Leão, Adelaide da Conceição Fonseca Passos, Anderson Manoel Herculano and Evander de Jesus Oliveira Batista
    Citation: BMC Complementary Medicine and Therapies 2022 22:11
    Content type: Research Published on:

  35. Epithelial-to-mesenchymal transition (EMT) is a pivotal cellular phenomenon involved in tumour metastasis and progression. In gastric cancer (GC), EMT is the main reason for recurrence and metastasis in postop...

    Authors: Guangtao Zhang, Zhaoyan Li, Jiahuan Dong, Weili Zhou, Zhanxia Zhang, Zujun Que, Xiaohong Zhu, Yan Xu, Nida Cao and Aiguang Zhao
    Citation: BMC Complementary Medicine and Therapies 2022 22:10
    Content type: Research Published on:

  36. Bletilla striata is the main medicine of many skin whitening classic formulas in traditional Chinese medicine (TCM) and is widely used in cosmetic industry recently. However, its active ingredients are still uncl...

    Authors: Yiyuan Luo, Juan Wang, Shuo Li, Yue Wu, Zhirui Wang, Shaojun Chen and Hongjiang Chen
    Citation: BMC Complementary Medicine and Therapies 2022 22:9
    Content type: Research Published on:

  37. The use of traditional medicinal plants in the management of diarrhea has long been practiced in Ethiopia. B. abyssinica fresen is one of the plants traditionally used to treat diarrhea whereas an in vivo study h...

    Authors: Mihret Ayalew, Azmeraw Bekele, Mestayet Geta Mengistie and Seyfe Asrade Atnafie
    Citation: BMC Complementary Medicine and Therapies 2022 22:8
    Content type: Research Published on:

  38. Patrinia scabra Bunge is a well-known herbal medicine for its favorable treatment on inflammatory diseases owing to its effective ingredients, in which iridoid glycoside plays an extremely significant role. This ...

    Authors: Quhuan Ma, Yanmei Lu, Yi Deng, Xiaodong Hu, Wanyu Li, Hongzhen Jia, Yuer Guo and Xiaofeng Shi
    Citation: BMC Complementary Medicine and Therapies 2022 22:7
    Content type: Research Published on:

  39. Quercus acuta Thunb. (Fagaceae) or Japanese evergreen oak is cultivated as an ornamental plant in South Korea, China, Japan, and Taiwan and used in traditional medicine. The acorn or fruit of Quercus acuta Thunb....

    Authors: Ji-Ae Hong, Donghyuk Bae, Kyo-Nyeo Oh, Dool-Ri Oh, Yujin Kim, Yonguk Kim, So Jeong Im, Eun-jin Choi, Seul-gi Lee, Moonjong Kim, Changsik Jeong and Chul Yung Choi
    Citation: BMC Complementary Medicine and Therapies 2022 22:6
    Content type: Research Published on:

  40. Trifolium pratense (red clover) ethanolic extract (TPEE) has been used as a popular over-the-counter remedy for the management of menopausal symptoms. Prolonged consumption of herbal extract has been shown to reg...

    Authors: Yixian Quah, Na-Hye Park, Eon-Bee Lee, Ki-Ja Lee, Jireh Chan Yi-Le, Md. Sekendar Ali, Seung-Hee Jang, Min-Jeong Kim, Seung-Jin Lee and Seung-Chun Park
    Citation: BMC Complementary Medicine and Therapies 2022 22:5
    Content type: Research Published on:

  41. Though Lippia javanica (Burm.f.) Spreng antioxidant activity has been demonstrated, its effect in protecting the brain from lead (Pb)-induced oxidative damage is unknown. This study investigated the effect of L. ...

    Authors: Zubair Suleman, Godwill A. Engwa, Mathulo Shauli, Hannibal T. Musarurwa, Ndinashe A. Katuruza and Constance R. Sewani-Rusike
    Citation: BMC Complementary Medicine and Therapies 2022 22:4
    Content type: Research Published on:

  42. Psychological risk factors have been recognised as potential, modifiable risk factors in the development and progression of cardiovascular disease (CVD). Tai Chi, a mind-body exercise, has the potential to imp...

    Authors: Guoyan Yang, Wenyuan Li, Nerida Klupp, Huijuan Cao, Jianping Liu, Alan Bensoussan, Hosen Kiat, Diana Karamacoska and Dennis Chang
    Citation: BMC Complementary Medicine and Therapies 2022 22:3
    Content type: Research article Published on:

  43. Whole-body vibration (WBV) training can provoke reactive muscle response and thus exert beneficial effects in various neurological patients. This study aimed to investigate the muscles activation and accelerat...

    Authors: Chia-Ming Chang, Chon-Haw Tsai, Ming-Kuei Lu, Hsin-Chun Tseng, Grace Lu, Bey-Ling Liu and Hsiu-Chen Lin
    Citation: BMC Complementary Medicine and Therapies 2022 22:2
    Content type: Research Published on:

  44. This study aimed to evaluate the cost-effectiveness of vitamin D supplementation in preventing type 2 diabetes mellitus (T2DM) among Iranian adolescents.

    Authors: Narges Zandieh, Mohsen Rezaei Hemami, Ali Darvishi, Seyed Mohammad Hasheminejad, Zahra Abdollahi, Maryam Zarei and Ramin Heshmat
    Citation: BMC Complementary Medicine and Therapies 2022 22:1
    Content type: Research Published on:

  45. In recent years, 1, 2, 4-triazole and its derivatives have been reported to be pharmacologically significant scaffolds. They possess analgesic, anti-tubercular, anti-inflammatory, anti-convulsant, anti-oxidant...

    Authors: Tabinda Azim, Muhammad Wasim, Muhammad Shoaib Akhtar and Irfan Akram
    Citation: BMC Complementary Medicine and Therapies 2021 21:304
    Content type: Research Published on:

  46. Despite the considerable advances made in the treatment of cancer, it remains a global threat. Tartrazine (E102) is a synthetic dye widely used in food industries; it has recently been shown to induce oxidativ...

    Authors: Stéphane Zingue, Elisabeth Louise Ndjengue Mindang, Florence Charline Awounfack, Abel Yanfou Kalgonbe, Moustapha Mohamet Kada, Dieudonné Njamen and Derek Tantoh Ndinteh
    Citation: BMC Complementary Medicine and Therapies 2021 21:303
    Content type: Research Published on:

  47. Oxidative stress (OS) and inflammation are the central pathogenic events in liver diseases. In this study, the protective and therapeutic role of Carica Papaya Linn. seeds extract (SE) was evaluated against the h...

    Authors: Nadia Z. Shaban, Sarah M. El-Kot, Olfat M. Awad, Afaf M. Hafez and Ghada M. Fouad
    Citation: BMC Complementary Medicine and Therapies 2021 21:302
    Content type: Research Published on:

  48. Benign prostatic hyperplasia (BPH) is a major urologic problem that mostly develops in older males. Oxidative stress and inflammation influence the occurrence of BPH. Berberine (BBR) is a natural ingredient th...

    Authors: Ehsan Shabani, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri and Hadi Kalantar
    Citation: BMC Complementary Medicine and Therapies 2021 21:301
    Content type: Research Published on:

  49. Antimicrobial drug resistance is a major public health threat that can render infections including wound and skin infections untreatable. The discovery of new antimicrobials is critical. Approaches to discover...

    Authors: Pauline McLoone, Aizhan Zhumbayeva, Sofiya Yunussova, Yerkhat Kaliyev, Ludmila Yevstafeva, Susan Verrall, Julie Sungurtas, Ceri Austin, J. Will Allwood and Gordon J. McDougall
    Citation: BMC Complementary Medicine and Therapies 2021 21:300
    Content type: Research article Published on:

  50. Recently, extracellular vesicles have come to the fore following their emerging role in cell communication, thanks to their ability to reach cells into the human body without dissipating their cargo, transferr...

    Authors: Riccardo Tassinari, Claudia Cavallini, Elena Olivi, Valentina Taglioli, Chiara Zannini, Orlando Ferroni and Carlo Ventura
    Citation: BMC Complementary Medicine and Therapies 2021 21:299
    Content type: Research Published on:
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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