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  1. Influenza A virus (IAV) is still a major health threat. The clinical manifestations of this infection are related to immune dysregulation, which causes morbidity and mortality. The usage of traditional medicat...

    Authors: Parvaneh Mehrbod, Samad Nejad Ebrahimi, Fatemeh Fotouhi, Fatemeh Eskandari, Jacobus N. Eloff, Lyndy J. McGaw and Folorunso O. Fasina

    Citation: BMC Complementary and Alternative Medicine 2019 19:346

    Content type: Research article

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  2. Cuphea ignea is one of the herbal resources belonging to Lythraceae family. Some species of this family have been used traditionally in South and Central America’s folk medicine for treating stomach disorders. Th...

    Authors: Amria M. Mousa, Nermin M. El-Sammad, Sherien K. Hassan, Abd El Nasser A. Madboli, Amani N. Hashim, Eman S. Moustafa, Sherien M. Bakry and Elsayed A. Elsayed

    Citation: BMC Complementary and Alternative Medicine 2019 19:345

    Content type: Research article

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  3. Mangosteen is a native fruit from Southeast Asia. It is rich in phenolic compounds such as xanthones, anthocyanins and phenolic acids. Mangosteen pericarp extract showed inhibitory activity towards pancreatic ...

    Authors: Noratirah Shazlin Muhamad Adyab, Asmah Rahmat, Noor Atiqah Aizan Abdul Kadir, Hawa Jaafar, Radhiah Shukri and Nurul Shazini Ramli

    Citation: BMC Complementary and Alternative Medicine 2019 19:344

    Content type: Research article

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  4. Chloranthus serratus (Chloranthaceae) has been used to treat bruises, rheumatoid and bone pain. However, the anti-inflammatory mechanisms of C. serratus in vitro have not been fully elucidated. The present study ...

    Authors: Shuping Sun, Yunyan Du, Chuanliu Yin, Xiaoguo Suo, Rui Wang, Rongping Xia and Xiaoping Zhang

    Citation: BMC Complementary and Alternative Medicine 2019 19:343

    Content type: Research article

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  5. Traditional and complementary medicine (T&CM) is commonly used by cancer patients in Northern Norway, in particular spiritual forms like traditional healing. T&CM is mainly used complementary to conventional c...

    Authors: Agnete Egilsdatter Kristoffersen, Trine Stub, Ann Ragnhild Broderstad and Anne Helen Hansen

    Citation: BMC Complementary and Alternative Medicine 2019 19:341

    Content type: Research article

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  6. Clinacanthus nutans Lindau (C. nutans) is a species of in Acanthaceae family and primarily used in South East Asian countries. C. nutans is well known as Sabah snake grass in Malaysia, and its leaves have diverse...

    Authors: Nik Mohd Afizan Nik Abd Rahman, M. Y. Nurliyana, M. N. F. Natasha Nur Afiqah, Mohd Azuraidi Osman, Muhajir Hamid and Mohd Azmi Mohd Lila

    Citation: BMC Complementary and Alternative Medicine 2019 19:340

    Content type: Research article

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  7. The dried fruits of Forsythia suspensa has generally been used to clear heat and detoxify in traditional Korean and Chinese medicine. Oxaliplatin is a first-line treatment chemotherapeutic agent for advanced colo...

    Authors: Jin-Mu Yi, Sarah Shin, No Soo Kim and Ok-Sun Bang

    Citation: BMC Complementary and Alternative Medicine 2019 19:339

    Content type: Research article

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  8. To investigate the potential of Catharanthus roseus leaf aqueous crude extract (CRACE) as a regulator of adipocyte development and function.

    Authors: Anuj Kumar Borah, Archana Singh, Rafika Yasmin, Robin Doley, Venkata Satish Kumar Mattaparthi and Sougata Saha

    Citation: BMC Complementary and Alternative Medicine 2019 19:338

    Content type: Research article

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  9. Tong-Xie-Yao-Fang (TXYF) has been shown to be effective in diarrhoea-predominant irritable bowel syndrome (IBS-D) patients. However, the underlying mechanism remains to be clarified. The aim of this study was ...

    Authors: Qiuke Hou, Yongquan Huang, Zhaoyang Zhu, Liu Liao, Xinlin Chen, Quanbin Han and Fengbin Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:337

    Content type: Research article

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  10. This study aims to assess the tolerability and safety of DQTM tablet, which contains a complex mixture of Salvia miltiorrhiza salvianolic acids and Panax notoginseng saponins.

    Authors: Zhong-ping Gou, Wei Zhang, Xiu-fang Liang, Ying Wang, Ju-hong Mou, Mei Li, Ya Zhang and Ping Feng

    Citation: BMC Complementary and Alternative Medicine 2019 19:336

    Content type: Research article

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  11. Concerns have been raised regarding the efficacy and safety resulting from the potential interactions of herbs with Western medications due to the use of both herbs and Western medicine by the general public. ...

    Authors: Chang-Shiann Wu, Yu-Huai Chen, Chi-Liang Chen, Sheng-Kan Chien, Nailis Syifa, Yu-Chun Hung, Kai-Jen Cheng, Shu-Chin Hu, Pei-Tzu Lo, Shun-Yung Lin and Tzu-Hua Wu

    Citation: BMC Complementary and Alternative Medicine 2019 19:335

    Content type: Database

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  12. Psoriasis, a recurrent, chronic inflammatory disorder of skin, is a common problem in middle age and elderly people. Thymoquinone (TQ), a lipid soluble benzoquinone is the major active ingredient of volatile o...

    Authors: Poonam Negi, Ishita Sharma, Chetna Hemrajani, Charul Rathore, Alpna Bisht, Kaisar Raza and O. P. Katare

    Citation: BMC Complementary and Alternative Medicine 2019 19:334

    Content type: Research article

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  13. Monotropein, astragalin, and spiraeoside (MAS) are active compounds extracted from medicinal herbs; monotropein from Morinda officinalis How (Rubiaceae), astragalin (kaempferol 3-O-glucoside) from Cuscuta chin...

    Authors: Keshab Kumar Karna, Bo Ram Choi, Jae Hyung You, Yu Seob Shin, Wan Shou Cui, Sung Won Lee, Ji Hoon Kim, Chul Young Kim, Hye Kyung Kim and Jong Kwan Park

    Citation: BMC Complementary and Alternative Medicine 2019 19:333

    Content type: Research article

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  14. Weight gain is common after breast cancer (BC) treatment and may increase the risk of disease recurrence. Complementary medicine (CM) use is high amongst BC patients. This paper describes the use of CM from a ...

    Authors: Carolyn Ee, Adele Elizabeth Cave, Dhevaksha Naidoo and John Boyages

    Citation: BMC Complementary and Alternative Medicine 2019 19:332

    Content type: Research article

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  15. Zingiber zerumbet rhizome and its bioactive metabolites have previously been reported to exhibit innumerable pharmacological properties particularly anti-inflammatory activities. In the present study, the 80% eth...

    Authors: Nabilah Mohammad Yaqoob Akhtar, Ibrahim Jantan, Laiba Arshad and Md. Areeful Haque

    Citation: BMC Complementary and Alternative Medicine 2019 19:331

    Content type: Research article

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  16. Endophytic fungi are a proven source of bioactive secondary metabolites that may provide lead compounds for novel drug discovery. In this study, crude extracts from fungal endophytes isolated from Datura stramoni...

    Authors: Kudzanai Ian Tapfuma, Nkemdinma Uche-Okereafor, Tendani Edith Sebola, Raeesa Hussan, Lukhanyo Mekuto, Maya Mellisa Makatini, Ezekiel Green and Vuyo Mavumengwana

    Citation: BMC Complementary and Alternative Medicine 2019 19:330

    Content type: Research article

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  17. Ulcerative colitis (UC) is a modern refractory disease, and its etiology has been difficult to discern. Studies have shown that UC is closely associated with the gut microbiota. Garidisan is composed of wild p...

    Authors: Ling-yan Pei, Yu-shi Ke, Huan-hu Zhao, Wei-zhi Liu, Lin Wang, Chao Jia, Meng-ni Shi, Qian-hui Fu, Jian Cui and Shu-chun Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:329

    Content type: Research article

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  18. In recent years, acupuncture has been increasingly integrated into pediatric care worldwide. However, recent epidemiological studies about pediatric users of acupuncture are lacking. The current study aimed to...

    Authors: Chieh Wang, Yu-Chen Lee, Mei-Yao Wu, Cheng-Li Lin, Mao-Feng Sun, Jaung-Geng Lin and Hung-Rong Yen

    Citation: BMC Complementary and Alternative Medicine 2019 19:328

    Content type: Research article

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  19. The control of biofilm adherence on tooth surface has always been the keystone of periodontal therapeutic systems. However, prevalence of gingivitis suggest inadequacy of self-performed oral hygiene measures a...

    Authors: Namratha Nayak, Jothi Varghese, Seema Shetty, Vinutha Bhat, Tejal Durgekar, Richard Lobo, Usha Y. Nayak and Vishwanath U

    Citation: BMC Complementary and Alternative Medicine 2019 19:327

    Content type: Research article

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  20. It has been testified that Diabetes mellitus (DM) has a close association with chronic inflammation and Toll-like Receptors (TLRs), and DM could be prevented by mulberry leaf. Therefore, a hypothesis came into...

    Authors: Simin Tian, Min Wang, Chenyue Liu, Hongbin Zhao and Baosheng Zhao

    Citation: BMC Complementary and Alternative Medicine 2019 19:326

    Content type: Research article

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  21. Osteoarthritis (OA) is an age-related joint disease with characteristics that involve the progressive degradation of articular cartilage and resulting chronic pain. Previously, we reported that Astragalus membran...

    Authors: Doo Jin Choi, Soo-Im Choi, Bo-Ram Choi, Young-Seob Lee, Dae Young Lee and Geum Soog Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:325

    Content type: Research article

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  22. The present study was designed to investigate the effects of Berberis vulgaris (BV) juice consumption on plasma levels of insulin-like growth factor (IGF-1), IGF-binding proteins (IGFBPs), and the expression of P...

    Authors: Saeed Pirouzpanah, Sanaz Asemani, Ali Shayanfar, Behzad Baradaran and Vahid Montazeri

    Citation: BMC Complementary and Alternative Medicine 2019 19:324

    Content type: Research article

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  23. Carpinus tschonoskii (CT) has been previously studied for various activities in the improvement of skin diseases. In the present study, we examined the in vitro anti-acne vulgaris (AV) effect of CT leaves (CTL) a...

    Authors: Jun Yin, In Hyoek Hwang and Min Won Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:323

    Content type: Research article

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  24. Platycodon grandiflorum is a flowering plant that is used in traditional medicine for treating pulmonary and respiratory disorders. It exerts various pharmacological effects, including immunomodulatory and anti-c...

    Authors: Eun-Mi Noh, Jeong-Mi Kim, Hak Yong Lee, Hyun-Kyung Song, Sang Ok Joung, Hye Jeong Yang, Min Jung Kim, Kang Sung Kim and Young-Rae Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:322

    Content type: Research article

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  25. This study aimed to develop and validate scales to assess attitudes towards patient’ s use of TCM (APUTCM) and to measure a communicative competence in TCM (CCTCM) among nurses.

    Authors: Hsiao-Yun Chang, Chia-Lun Lo and Yun-Ying Hung

    Citation: BMC Complementary and Alternative Medicine 2019 19:321

    Content type: Research article

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  26. Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug...

    Authors: Chongyang Ma, Xueqian Wang, Tian Xu, Xue Yu, Shuang Zhang, Shuling Liu, Yushan Gao, Shuning Fan, Changxiang Li, Changming Zhai, Fafeng Cheng and Qingguo Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:320

    Content type: Research article

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  27. ChondroT is a complex herbal medicine consisting of water extracts of Ostericum koreanum (Maxim.) Kitag., Lonicera japonica Thunb., Angelica gigas Nakai, Clematis manshurica Rupr., and Phellodendron amurense Rupr...

    Authors: Rui Hong Guo, Seon-Jong Kim, Chan-hun Choi, Chang-su Na, Bok Yun Kang and Young Ran Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:319

    Content type: Research article

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  28. Altered cellular metabolism is considered to be one of the hallmarks of cancer (Coller, Am J Pathol 184:4–17, 2014; Kim and Bae, Curr Opin Hematol 25:52–59, 2018). However, few studies have investigated the ro...

    Authors: Wei Liu, Zi-ming Zhao, Yuan-liang Liu, Hua-feng Pan and Li-zhu Lin

    Citation: BMC Complementary and Alternative Medicine 2019 19:318

    Content type: Research article

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  29. Doxorubicin (DOX) is a chemotherapy drug for malignant tumors. The clinical application of DOX is limited due to its dosage relative cardiotoxicity. Oxidative damage and cardiac inflammation appear to be invol...

    Authors: Sheng Zhang, Zhen-Qiang You, Lin Yang, Li-Li Li, You-Ping Wu, Li-Qiang Gu and Yan-Fei Xin

    Citation: BMC Complementary and Alternative Medicine 2019 19:317

    Content type: Research article

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  30. Icariin (ICA) is the major active ingredient extracted from Chinese herbal medicine Epimedium, which has the effects of improving cardiovascular function, inducing tumor cell differentiation and increasing bon...

    Authors: Lingli Hu, Lulu Li, Hongying Zhang, Qiuping Li, Shan Jiang, Jian Qiu, Jing Sun and Jingcheng Dong

    Citation: BMC Complementary and Alternative Medicine 2019 19:316

    Content type: Research article

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  31. Pseudomonas aeruginosa has become a main cause of Gram-negative infection, particularly in patients with compromised immunity. High rates of resistance to antibiotics are associated with nosocomial infections cau...

    Authors: Molly Mombeshora and Stanley Mukanganyama

    Citation: BMC Complementary and Alternative Medicine 2019 19:315

    Content type: Research article

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  32. Inflammation is recognized as the key pathological mechanism of type 2 diabetes. The hypoglyceamic effects of berberine (BBR) are related to the inhibition of the inflammatory response, but the mechanism is no...

    Authors: Jing Gong, Jingbin Li, Hui Dong, Guang Chen, Xin Qin, Meilin Hu, Fen Yuan, Ke Fang, Dingkun Wang, Shujun Jiang, Yan Zhao, Wenya Huang, Zhaoyi Huang and Fuer Lu

    Citation: BMC Complementary and Alternative Medicine 2019 19:314

    Content type: Research article

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  33. Jianpi-yangwei (JPYW), a traditional Chinese medicine (TCM), helps to nourish the stomach and spleen and is primarily used to treat functional declines related to aging. This study aimed to explore the antiagi...

    Authors: Liling Zeng, Zhimin Yang, Tianchan Yun, Shaoyi Fan, Zhong Pei, Ziwen Chen, Chen Sun and Fuping Xu

    Citation: BMC Complementary and Alternative Medicine 2019 19:313

    Content type: Research article

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  34. Cervical cancer is the second-leading cause of cancer-related mortality in females. Coix lacryma-jobi L. var. ma-yuen (Rom.Caill.) Stapf ex Hook. f. is the most widely recognized medicinal herb for its remedial e...

    Authors: Eun Suk Son, Se-Hee Kim, Young Ock Kim, Young Eun Lee, Sun Young Kyung, Sung Hwan Jeong, Yu Jin Kim and Jeong-Woong Park

    Citation: BMC Complementary and Alternative Medicine 2019 19:312

    Content type: Research article

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  35. To provide evidence for medical management of chronic idiopathic constipation (CIC) in China based on comparisons of all clinical practical interventions using Bayesian network meta-analysis.

    Authors: Qingyang Shi, Lizi Tan, Chunxiang Liu, Huijun Wang, Junhua Zhang, Hui Wang and Jingbo Zhai

    Citation: BMC Complementary and Alternative Medicine 2019 19:311

    Content type: Research article

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  36. Heracleum moellendorffii roots (HM-R) have been long treated for inflammatory diseases such as arthritis, backache and fever. However, an anti-inflammatory effect and the specific mechanism of HM-R were not yet c...

    Authors: Ha Na Kim, Jeong Dong Kim, Joo Ho Yeo, Ho-Jun Son, Su Bin Park, Gwang Hun Park, Hyun Ji Eo and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2019 19:310

    Content type: Research article

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  37. Sheng Mai San (SMS) has been proven to exhibit cardio-protective effects. This study aimed to explore the molecular mechanisms of SMS on hyperglycaemia (HG)-induced apoptosis in H9C2 cells.

    Authors: Bing Pang, Li-Wei Shi, Li-juan Du, Yun-Chu Li, Mei-Zhen Zhang and Qing Ni

    Citation: BMC Complementary and Alternative Medicine 2019 19:309

    Content type: Research article

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  38. Dental caries is a biofilm-diet-dependent worldwide public health problem, and approaches against microorganisms in cariogenic biofilms are necessary.

    Authors: Sabrina M. Ribeiro, Érick D. O. Fratucelli, Paula C. P. Bueno, Marlene Kelly V. de Castro, Amanda Alcalá Francisco, Alberto José Cavalheiro and Marlise I. Klein

    Citation: BMC Complementary and Alternative Medicine 2019 19:308

    Content type: Research article

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  39. Asphodelus tenuifolius Cav. (Asphodelaceae) has traditional reputability in treatment of diarrhea and constipation but no scientific study has been reported for its gastrointestinal effects. Present study was con...

    Authors: Naveed Aslam and Khalid Hussain Janbaz

    Citation: BMC Complementary and Alternative Medicine 2019 19:307

    Content type: Research article

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  40. The chemical composition of many essential oils indicates that they have sedative and hypnotic effects, but there is still a lack of systematic studies on the sedative and hypnotic effects of essential oils. I...

    Authors: Yu Zhong, Qin Zheng, Pengyi Hu, Xiaoying Huang, Ming Yang, Guilin Ren, Qing Du, Jun Luo, Kenan Zhang, Jing Li, Haixia Wu, Yuanyuan Guo and Shanshan Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:306

    Content type: Research article

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  41. Patient-centered culturally sensitive health care (PC-CSHC) has emerged as a primary approach to health care. This care focuses on the cultural diversity of the patients rather than the views of the health car...

    Authors: Agnete E. Kristoffersen, Ann Ragnhild Broderstad, Frauke Musial and Trine Stub

    Citation: BMC Complementary and Alternative Medicine 2019 19:305

    Content type: Research article

    Published on:

  42. The aim of the present study was to examine the effects of the Bolbostemma paniculatum (Maxim.) Franquet (BP) active compound, BP total saponins (BPTS), on MDA-MB-231 cells, and investigate the underlying mechani...

    Authors: Jian-Wei Dou, Rong-Guo Shang, Xiao-Qin Lei, Kang-Le Li, Zhan-Zi Guo, Kai Ye, Xiao-Juan Yang, Yu-Wei Li, Yun-Yun Zhou, Jia Yao and Qian Huang

    Citation: BMC Complementary and Alternative Medicine 2019 19:304

    Content type: Research article

    Published on:

  43. Candida albicans is an opportunistic pathogen that causes oral candidiasis and denture stomatitis. It has also been reported to infect oral mucositis lesions in patients who suffer from cancer affecting the head ...

    Authors: Marie-Pier Veilleux and Daniel Grenier

    Citation: BMC Complementary and Alternative Medicine 2019 19:303

    Content type: Research article

    Published on:

  44. Following publication of the original article [1], the author reported that Tables 3 and 4 were incorrect due to a production error.

    Authors: Tayyaba Afsar, Suhail Razak, Ali Almajwal and Muhammad Rashid Khan

    Citation: BMC Complementary and Alternative Medicine 2019 19:302

    Content type: Correction

    Published on:

    The original article was published in BMC Complementary and Alternative Medicine 2018 18:49

  45. Both doctors’ and patients’ opinions are important in the process of treatment and healthcare of Chinese medicine. This study is to compare patients’ and doctors’ treatment satisfaction over the course of two ...

    Authors: Yanhong Zhang, Jiqian Fang, Wei Gao, Ying Han, Runshun Zhang, Liyun He and Baoyan Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:300

    Content type: Research article

    Published on:

  46. Physical identical and pharmacological inert are the basic requirements for placebo design, which are essential in clinical trials to evaluate the efficacy of an intervention. However, it is difficult to makeu...

    Authors: Xuan Zhang, Ran Tian, Chen Zhao, Xudong Tang, Aiping Lu and Zhaoxiang Bian

    Citation: BMC Complementary and Alternative Medicine 2019 19:299

    Content type: Research article

    Published on:

  47. For decades, bioprospecting has proven to be useful for the identification of compounds with pharmacological potential. Considering the great diversity of Colombian plants and the serious worldwide public heal...

    Authors: Andrea Isabel Trujillo-Correa, Diana Carolina Quintero-Gil, Fredyc Diaz-Castillo, Winston Quiñones, Sara M. Robledo and Marlen Martinez-Gutierrez

    Citation: BMC Complementary and Alternative Medicine 2019 19:298

    Content type: Research article

    Published on:

  48. Radix isatidis (Isatis indigotica Fort.) is an ancient medicinal herb, which has been applied to the prevention and treatment of influenza virus since ancient times. In recent years, the antioxidant activity of R...

    Authors: Ping Xiao, Hongzhi Huang, Xiang Li, Jianwei Chen and Jin-ao Duan

    Citation: BMC Complementary and Alternative Medicine 2019 19:297

    Content type: Research article

    Published on:

  49. Bergenia ciliata is a medicinal plant used for the treatment of diarrhea, vomiting, fever, cough, diabetes, cancer, pulmonary disorders and wound healing.

    Authors: Roheena Zafar, Habib Ullah, Muhammad Zahoor and Abdul Sadiq

    Citation: BMC Complementary and Alternative Medicine 2019 19:296

    Content type: Research article

    Published on:

  50. NGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus. Inhibition of NGF-TrkA is a known strategy for the treatment of pruri...

    Authors: Yueling Zhong, Hong Xu, Yi Zhong, Xuemiao Zhang, Ting Zeng, Limei Li, Gaojie Xu, Minhui Li, Jin Liu and Tai Yang

    Citation: BMC Complementary and Alternative Medicine 2019 19:295

    Content type: Research article

    Published on:

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