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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Origanum majorana L. protects against neuroinflammation-mediated cognitive impairment: a phyto-pharmacological study

Fig. 6

Immunohistochemical analysis of COX-2 in the cerebral cortex. Deconvoluted images of DAB staining (second row) was produced by IHC profiler, and the percentage contributions was calculated relative to each image pixel intensity as high positive, positive, low positive, and negative pixels. An automated score of low positive is found for the control group, LPS group, and OM group. However, the generated automated score for LPS + OM group is negative. For further quantitative analysis, calculation of IHC optical density score was done. LPS group scored 1.8461 compared with 1.472 for control group, 1.1358 for LPS + OM group, and 1.7966 for OM group. Our results show that COX-2 expression was attenuated under the effect of OM extract (COX-2 immunostaining, × 80) (n = 3)

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