Comprehensive chemical profiling of Bassia indica Wight. aerial parts extract using UPLC-ESI–MS/MS, and its antiparasitic activity in Trichinella spiralis infected mice: in silico supported in vivo study

Table 2 The counts of T. spiralis adult worm and encysted larvae per gram muscle

*T. spiralis* phases	Mean ± SD	P-value	% Reduction
Intestinal Phase (Day 6 post-infection)
G-III	89 ± 8.5
G-IV	51 ± 8.4	< 0.05*	42.7
G-V_a	46.5 ± 3.5	< 0.01**	47.8
G-VI_a	7 ± 1.4	< 0.001***	92.1
Muscular Phase (Day 35 post-infection)
G-III	7920 ± 973.1
G-IV	1525 ± 330.4	< 0.001***	80.7
G-V_b	2166.7 ± 351.2	< 0.001***	72.7
G-V_c	1600 ± 556.8	< 0.001***	79.8
G-VI_b	700 ± 173.2	< 0.001***	91.2
G-VI_c	600 ± 100	< 0.001***	92.4

P-value is significantly different comparing with control, depending on Student t-test. *Initial P-value < 0.05 is significant. **Initial P-value < 0.01 is highly significant. G-I: negative control, G-III: Positive control (infected untreated), G-IV: prophylactically treated with B. indica BuOH frac., for seven days before infection, G-V: infected and treated with B. indica BuOH frac., G-VI: Infected and treated with albendazole

ISSN: 2662-7671