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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Amygdalin-folic acid-nanoparticles inhibit the proliferation of breast cancer and enhance the effect of radiotherapy through the modulation of tumor-promoting factors/ immunosuppressive modulators in vitro

Fig. 6

Expression of TGF-β, VEGF, INF-g, IL-2, and IL-6 in BC cells upon treatment with Amy-F and/or exposed to 4 Gy γ-irradiation. a, b % change in the expression of TGF-β in Amy-F and/or RT treated MCF-7 and MDA-MB-231 cells, respectively; c Fold change in the expression ratio of VEGF in Amy-F and/or RT treated MCF-7 and MDA-MB-231 cells, respectively; d % change in the expression of INF-g in Amy-F and/or RT treated MCF-7 and MDA-MB-231 cells, respectively; e Fold change in the expression ratio of IL-2 in Amy-F and/or RT treated MCF-7 and MDA-MB-231 cells, respectively; f Fold change in the expression ratio of IL-6 in Amy-F and/or RT treated MCF-7 and MDA-MB-231 cells, respectively. Data are mean ± SEM, a1p < 0.001, a2p < 0.01, a3p < 0.05 vs. Control group; b1p < 0.001, b2p < 0.01, b3p < 0.05 vs. Amy-F group; c1p < 0.001, c2p < 0.01, c3p < 0.05 vs. RT group

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