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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

Fig. 6

KJG ameliorates TLR4-induced neuroinflammation in CUMS mice via the PI3K/AKT/FOXO1 pathway. WB analysis for TLR4, p-PI3K, PI3K, p-AKT, AKT, p-FOXO1, FOXO1, PTEN, and p-PTEN in hippocampal tissues (n = 3). One-way ANOVA or unpaired t-tests: # P < 0.05, ## P < 0.01, ### P < 0.001 vs. control group; * P < 0.05, ** P < 0.01, *** P < 0.001 vs. CUMS group; & P < 0.05, && P < 0.01, &&& P < 0.001, vs. CUMS + KJG8 group

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