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Table 5 Visceral malformations found in the offspring of females treated with the ethanolic extract of S. lachnostachys (EESl)

From: The ethanolic extract of Salvia lachnostachys Benth is not maternotoxic, does not alter reproductive performance, but has teratogenic potential

Visceral Malformation

Experimental groups (mg/kg)

Parameters

Control

EESl 100

EESl 1000

Analyzed fetuses

55

53

53

Normal Fetuses

44

35

45

Brain—Hydrocephalus

 Mild Hydrocephalus

10

7

6

 Moderate Hydrocephalus

1

2

0

 Frequency of Malformations

11

9

6

 % M.F

20

16.98

11.32

Urogenital Region—Hydronephrosis

 Mild Hydronephrosis

0

8*

1

 Absence of Right Kidney

0

1

0

 Frequency of Malformations

0

9*

1

 % M.F

0

16.98*

1.88

  1. Legend: % M. F—the percentage of fetuses with malformation
  2. *Statistical difference (Statistical test: Chi-square; p < 0.05)