The efficacy and safety of Sanqi Qushi Granule in patients with idiopathic membranous nephropathy ——protocol of a multicenter, randomized control trial (SQ-AUTUMN)

Table 1 Schedule of enrollment, intervention, and assessment

Study Period
	Baseline	Intervention phase						Follow-up phase
Time point	0	M1	M2	M3	M4	M5	M6	M7	M8	M9	M10	M11	M12
Enrollment
Eligibility screening	×
Informed consent	×
Randomization	×
Interventions
Cyclical CTX/glucocorticoids therapy + SQG	×	×	×	×	×	×	×
Cyclical CTX/glucocorticoids therapy + placebo	×	×	×	×	×	×	×
Assessments
Demographic data	×
Medical history	×
Concomitant medication	×	×	×	×	×	×	×	×	×	×	×	×	×
Symptoms and signs	×	×	×	×	×	×	×	×	×	×	×	×	×
Physical examination	×	×	×	×	×	×	×	×	×	×	×	×	×
Routine blood and urine	×	×	×	×	×	×	×	×	×	×	×	×	×
24 h urinary total protein	×	×	×	×	×	×	×	×	×	×	×	×	×
Renal function test	×	×	×	×	×	×	×	×	×	×	×	×	×
Urine Protein:Creatinine Ratio	×	×	×	×	×	×	×	×	×	×	×	×	×
Serum anti-PLA2R levels	×			×			×			×			×
Liver function test	×	×	×	×	×	×	×	×	×	×	×	×	×
Serum albumin	×	×	×	×	×	×	×	×	×	×	×	×	×
Blood lipid	×	×	×	×	×	×	×	×	×	×	×	×	×
Blood glucose	×	×	×	×	×	×	×	×	×	×	×	×	×
Serum potassium	×	×	×	×	×	×	×	×	×	×	×	×	×
Electrocardiogram	×			×			×			×			×
Chest X-ray	×			×			×			×			×
Dampness Syndrome Scale of Chinese Medicine	×	×	×	×	×	×	×	×	×	×	×	×	×
Adverse events		×	×	×	×	×	×	×	×	×	×	×	×

ISSN: 2662-7671