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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation

Fig. 7

Osthole affects bladder cancer cell migration and EMT by inhibiting PI3K-AKT-MTOR and JAK-STAT3 pathway. A The images of wound healing assays in 5637 cell line. B The images of wound healing assays in 253 J cell line. C The images of transwell asssays in bladder cancer cells. D The migration and invasion related proteins (MMP2,MMP9) were detected by western blot. E The EMT related biomarkers (E-cadherin, N-cadherin, Snail) were detected by western blot. F The PI3K-AKT-MTOR pathway and JAK-STAT3 pathway related protein were detected by western blot

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