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Table 6 Skeletal (limb bones) malformations of 20 days old rat fetuses following treatment of pregnant rats with 70% ethanol extract of M. stenopetala leaf

From: Toxic effects of 70% ethanol extract of Moringa stenopetala leaf (Baker f.) Cufod. (Moringaceae) on fetus and placenta of pregnant Wistar rats

Groups

Percent of skeletal malformations of limb bones

Metacarpusa

Forelimb phalangesb

Metatarsala

Hindlimb phalangesb

G-I: ((n = 27)

7.4

18.5

0

18.5

G-II (n = 27)

11.1

22.2

7.4

33.3

G-III (n = 27)

14.8

25.9

11.1

40.7*

G-IV (n = 27)

11.1

11.1

0

18.5

G-V (n = 27)

7.4

11.1

0

14.8

  1. Results are presented as a percentage (%) of skeletal malformations (chi-square test)
  2. *Significantly different compared with 250 mg/kg treated and pair-fed control groups (P-value < 0.05)
  3. aPresence of ≤ 3 metacarpus and metatarsus
  4. bAbsent proximal phalanges