Table 1 Cytotoxicity EC100 values (µg/mL), effective anti-inflammatory concentrations (µg/mL) and TNF-α (µg/mL), INF-γ (µg/mL) and IL-1β (µg/mL) levels of the tested extracts
Sample | Cytotoxicity EC100 (µg/mL) ± SD | Effective anti-inflammatory concentrations (µg/mL) ± SD | TNF-α (µg/mL) ± SD | INF-γ (µg/mL) ± SD | IL-1β (µg/mL) ± SD |
|---|---|---|---|---|---|
Alternaria alternata MN615420 | 27.83 ± 2.33 | 0.20 ± 0.003 | 0.20 ± 0.004 | 0.18 ± 0.008 | 0.12 ± 0.008 |
Alternaria alternata MZ066724 | 20.38 ± 0.98 | 0.54 ± 0.06 | 0.42 ± 0.08 | 0.36 ± 0.01 | 0.40 ± 0.02 |
Alternaria infectoria MT573465 | 18.99 ± 1.02 | 0.33 ± 0.01 | 0.30 ± 0.04 | 0.15 ± 0.009 | 0.24 ± 0.03 |
Stemphylium sp. MT084051 | 7.42 ± 0.89 | 0.34 ± 0.02 | 0.28 ± 0.03 | 0.19 ± 0.007 | 0.11 ± 0.007 |
Stemphylium simmonsii MN401378 | 5.97 ± 0.58 | 0.55 ± 0.07 | 0.49 ± 0.04 | 0.49 ± 0.02 | 0.37 ± 0.05 |
Fusarium equiseti MK968015 | 9.76 ± 1.65 | 0.51 ± 0.06 | 0.41 ± 0.05 | 0.24 ± 0.01 | 0.29 ± 0.06 |
Piroxicam | 17.58 ± 2.69 | 1.01 ± 0.25 | 0.57 ± 0.01 | 1.36 ± 0.30 | 0.66 ± 0.10 |
LPS-stimulated WBCs | - | - | 2.36 ± 0.85 | 5.69 ± 1.02 | 2.69 ± 0.58 |
Normal cells (control) | - | - | 0.79 ± 0.03 | 2.51 ± 0.58 | 1.16 ± 0.085 |