Table 1 PA increases melanoma cells’ drug sensitivities to DTIC. A375 and SK-MEL-28 cells were treated with a range of concentrations of DTIC with or without PA for 72 h. Cell viability and IC50 were detected by CCK8 assay
|  | IC50(µM,mean ± SD) | p value | IC50(µM,mean ± SD) | p value | ||
|---|---|---|---|---|---|---|
A375 | A375 + 80µM PA | SK-MEL-28 | SK-MEL-28 + 100µM PA | |||
DTIC | 15.40 ± 1.39 | 0.28 ± 0.07 | P < 0.01 | 309.55 ± 5.73 | 98.20 ± 0.37 | P < 0.01 |