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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells

Fig. 1

Protocatechuic aldehyde synergistically enhances DTIC cytotoxicity to melanoma cells. A Dose-response curves for PA, DTIC or DTIC combined with a certain concentration of PA for 72 h in A375 and SK-MEL-28 cells. B Dose-response curves for A375 and SK-MEL-28 cells treated with a range of concentrations of PA, DTIC or their combinations. C Synergy scores were calculated from the data represented in B for PA combined with DTIC for A375 and SK-MEL-28 cells. The left panel represents the synergy scores from ZIP model. The right panel represents the synergy scores from Bliss model. **** p<0.0001

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