Antiviral and ROS scavenging potential of Carica papaya Linn and Psidium guajava leaves extract against HIV-1 infection

Table 2 Summary of CC₅₀, EC₅₀ and SI of Carica papaya L and Psidium guajava leaf extracts

Extract(s)	Cell Cytotoxicity (^aCC50, mg/ml)	Anti-HIV-1 Activity Cell—Associated Assay				Anti-HIV-1 Activity Cell—Free Assay
		HIV-1_VB028		HIV-1_UG070		HIV-1_VB028		HIV-1_UG070
		^bEC₅₀	^cS.I	EC₅₀	S.I	EC₅₀	S.I	EC₅₀	S.I
C. papaya L	2.07	1.03	2.009	1.25	1.66	1.075	1.926	1.176	1.760
P. guajava	1.84	0.07	26.28	0.085	21.65	0.073	25.21	0.054	34.07

^aCC₅₀: The cytotoxic concentration of the extracts that caused the reduction of viable cells by 50%
^bEC₅₀: The effective concentration of the extracts that resulted in 50% inhibition in HIV-1 infection
^cS.I.: Selective Index is the ratio of cell cytotoxicity to its biological activity i.e. CC₅₀/EC₅₀
All data presented are averages of three independent experiments

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