Fig. 5

Combination therapy of methyl gallate and NK-92 cells suppressed re-proliferation of ovarian cancer cells. A, B OVCAR-5 cells were pretreated for 24 h with 0.1 mg/mL methyl gallate (MG), and (C, D) SK-OV-3 cells were pre-treated for 48 h with 0.02 mg/mL methyl gallate (MG). Cells were then co-cultured in the presence or absence of NK-92 cells at E:T ratio of 1:4. Untreated cells co-cultured in the presence or absence of NK-92 cells served as control. Cells were counted every 3 days. Values presented are the average ± SD of three independent experiments performed in triplicates. ***p < 0.001