A clinical trial on anti-diabetic efficacy of submerged culture medium of Ceriporia lacerata mycelium

Table 4 Analysis of OGTT from baseline to 12 weeks (ITT)

		Placebo	CLM	p value^a	p value^b
		Mean ± SD		p value^a	p value^b
Blood glucose	Baseline	148.0 ± 47.3	150.4 ± 58.6	0.848
	after 12 weeks	138.5 ± 57.3	140.8 ± 51.6	0.862
	Difference^c	-9.5 ± 10.0	-9.6 ± 7.0	0.990
	p value^d	0.390	0.186		0.948
HbA1c	Baseline	5.7 ± 0.6	5.8 ± 0.5	0.519
	after 12 weeks	5.8 ± 0.5	5.8 ± 0.5	0.987
	Difference^c	-0.1 ± 0.1	0.0 ± 0.0	0.274
	p value^d	0.891	0.126		0.324
Insulin	Baseline	6.6 ± 4.8	7.3 ± 5.5	0.599
	after 12 weeks	7.2 ± 7.8	5.0 ± 4.9	0.149
	Difference^c	-0.6 ± 3.0	-2.3 ± 0.6	0.090
	p value^d	0.604	0.062		0.137
C-peptide	Baseline	2.2 ± 1.0	2.4 ± 1.4	0.542
	after 12 weeks	2.2 ± 1.4	1.7 ± 0.7	0.048
	Difference^c	0.0 ± 0.4	-0.7 ± 0.7	0.014^*	0.015^*
	p value^d	0.729	0.002^*

^aCompared between groups: p-value by independent t-test
^bCompared between groups: p-value by ANCOVA (adjustment with baseline and calorie)
^cDifference between the values of baseline and after 12 weeks
^dCompared within groups: p-value by paired t-test
^*p < 0.05

ISSN: 2662-7671