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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: In utero and postnatal exposure to Foeniculum vulgare and Linum usitatissimum seed extracts: modifications of key enzymes involved in epigenetic regulation and estrogen receptors expression in the offspring’s ovaries of NMRI mice

Fig. 4

Estrogen receptors expression level in the F1 ovarian tissue after exposure to the fennel and flaxseed extracts. Relative expression levels of both isoforms of estrogen receptors included of ESRα and ESRβ in the left ovarian of adult mice after treatment with hydroalcoholic extract of fennel and flax seed, either alone or in combination showed a marked decrease in the expression level of both ESRs, although the expression level of ESR alpha increased significantly in the concomitantly-exposed mice. The mRNA level of each sample was normalized against β actin mRNA level. Data are presented as mean ± SEM. * shows p ≤ 0.05. One-Way ANOVA test followed by Tukey post-hoc was carried out for ESR alpha expression level analysis and Kruskal–Wallis test was used for ESR beta. The authors performed three replications

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