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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Thymoquinone, piperine, and sorafenib combinations attenuate liver and breast cancers progression: epigenetic and molecular docking approaches

Fig. 3

Assessment of cell death mechanism in HepG2 after thymoquinone (TQ), piperine (PIP), and sorafenib (SOR) alone and combination treatments for 48 hs. Cells were double stained with annexin V-FITC and PI, analyzed by flow cytometry. Representative dot plots are shown (A). Percentage of live cells, necrotic cells and apoptotic (early + late) (B, C and D). Cell populations were plotted and represented collectively as percentage of total events. Data are expressed as the mean ± SEM; n = 3. Means within columns carrying * are significantly different at (p ˂0.05), ** (p ˂ 0.01), *** (p ˂ 0.001) and **** (p ˂ 0.0001)

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