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Table 5 In vitro antiplasmodial activity of Sonchus arvensis L. leaf extracts against P. falciparum strain 3D7

From: In vitro and in vivo antiplasmodial activities of leaf extracts from Sonchus arvensis L.

No

Extract

% Inhibition at each concentration (μg/mL)

IC50 (µg/mL)

100

10

1

0.1

0.01

0.001

1

n-Hexane

100.00 ± 0.00

53.81 ± 0.65

45.21 ± 1.94

35.79 ± 3.90

31.73 ± 3.73

-

5.12 ± 2.34

2

Ethyl acetate

100.00 ± 0.00

75.82 ± 1.93

65.68 ± 3.09

44.89 ± 9.73

34.84 ± 1.49

-

2.92 ± 3.27

3

Ethanol

93.60 ± 0.53

27.54 ± 2.51

23.50 ± 1.11

13.09 ± 1.49

6.94 ± 0.36

-

8.03 ± 1.23

4

Chloroquine diphosphate

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

79.76 ± 4.51

40.49 ± 5.29

17.17 ± 2.31

0.01 ± 0.00

  1. Note: The data were represented as mean ± standard deviation (SD), n = 3