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Table 4 The predicting factors for potential herb-drug interaction among cancer patients

From: The prevalence and predictors of herb-drug interactions among Iranian cancer patients during chemotherapy courses

Variable

Level of variable

AORa

(95% CIb)

P-value

Number of chemotherapeutic agentsc

1.92

(1.43–2.58)

 < 0.0001

Number of herbal medicinesc

1.15

(1.06–1.24)

 < 0.0001

Cancer site

Breast

1

–

Gastrointestinal

0.08

(0.02–0.30)

 < 0.0001

Lymphoma and hematologic tumors

0.41

(0.08–1.92)

0.26

Gynecologic

0.28

(0.06–1.32)

0.27

Thorax

0.10

(0.01–0.61)

0.01

Other sites

0.58

(0.09–3.55)

0.56

Clinical stage

I

1

–

II

2.66

(0.45–15.52)

0.27

III

3.42

(0.59–19.74)

0.16

IV

8.42

(1.10–64.04)

0.04

Unclear

4.83

(0.93–25.03)

0.06

Recurrence status

Negative

1

–

Positive

0.40

(0.11–1.36)

0.14

Unclear

0.06

(0.005–0.67)

0.02

Pain

Negative

1

–

Positive

2.22

(1.00–4.94)

0.04

  1. aAdjusted Odds Ratio
  2. bConfidence Intervals
  3. cThese variables were considered as continuous in the analysis