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Table 4 Effect of P. peruviana L. calyces extract and butanol fraction on body weight and kidney weight in Cd-induced nephrotoxicity in rats

From: Nephroprotective effect of Physalis peruviana L. calyx extract and its butanolic fraction against cadmium chloride toxicity in rats and molecular docking of isolated compounds

Groups and doses (mg/kg)

Body weight (g)

Kidney weight (g)

Initial

Final

Control

198.00 ± 5.31

209.85 ± 6.67

1.00 ± 0.02

CdCl2 3

209.71 ± 6.44

197.85 ± 6.58

1.15 ± 0.01a

AME 500

200.14 ± 4.98

203.57 ± 5.40

0.99 ± 0.02b

AME 1000

198.85 ± 5.28

204.28 ± 4.61

0.96 ± 0.02b

Bu.F. 500

196.71 ± 4.82

201.28 ± 4.52

1.00 ± 0.02b

Bu.F. 1000

193.57 ± 4.11

198.00 ± 3.79

0.99 ± 0.01b

Silymarin 150

193.71 ± 1.97

202.14 ± 2.23

0.01b

  1. Data presented as: Mean ± SE (n = 6)
  2. CdCl2 Cadmium chloride, AME Aqueous Methanolic Extract, Bu.F Butanol Fraction
  3. a Significant from control group at P < 0.05
  4. b Significant from CdCl2 group at P < 0.05