Skip to main content
Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Nephroprotective effect of Physalis peruviana L. calyx extract and its butanolic fraction against cadmium chloride toxicity in rats and molecular docking of isolated compounds

Fig. 5

Effect of AME and Bu.F. of P. peruviana L. calyx on histopathological examinations with hematoxylin and eosin (H&E) in CdCl2-induced nephrotoxicity in rats: Control: Normal distal convoluted tubules (arrow), proximal convoluted tubules (red arrow), glomeruli (asterisk), and urinary spaces (short arrow); CdCl2-I: Inflammatory infiltration (arrow), glomerular hypercellularity (asterisk) with narrow urinary spaces (arrowhead); CdCl2-II: Interstitial hemorrhage (arrows), and desquamation of tubular epithelial cells (arrowhead); AME 500–1: Renal structure appeared nearly to normal form; AME 500-II: Inflammatory infiltration (arrow), glomerular hypercellularity (asterisk), with narrow urinary spaces (arrow head), and tubular interstitial hemorrhage (arrowheads); AME 1000-I: Renal structure appeared nearly to normal form; AME 1000-II: Glomerular hypercellularity (asterisk) with narrow urinary spaces (arrow head), and interstitial Hemorrhage (arrows); Bu.F. 500-I: More or less normal renal corpuscles (arrow head), and renal tubular degenerative changes (arrow); Bu.F. 500-II: Normal renal corpuscles and tubules; Bu.F. 1000: Renal corpuscles and the renal tubules appeared nearly too normal form; Silymarin-I: Renal structure appeared nearly to normal form; Silymarin-II: Glomerular congestion and hypercellularity and narrow urinary space (arrow head), and tubular degenerative changes with pyknotic nuclei (arrow) (Scale Bar 100 µm). CdCl2: Cadmium chloride, AME: Aqueous Methanolic Extract, Bu.F: Butanol Fraction

Back to article page