Fig. 5From: Nephroprotective effect of Physalis peruviana L. calyx extract and its butanolic fraction against cadmium chloride toxicity in rats and molecular docking of isolated compoundsEffect of AME and Bu.F. of P. peruviana L. calyx on histopathological examinations with hematoxylin and eosin (H&E) in CdCl2-induced nephrotoxicity in rats: Control: Normal distal convoluted tubules (arrow), proximal convoluted tubules (red arrow), glomeruli (asterisk), and urinary spaces (short arrow); CdCl2-I: Inflammatory infiltration (arrow), glomerular hypercellularity (asterisk) with narrow urinary spaces (arrowhead); CdCl2-II: Interstitial hemorrhage (arrows), and desquamation of tubular epithelial cells (arrowhead); AME 500–1: Renal structure appeared nearly to normal form; AME 500-II: Inflammatory infiltration (arrow), glomerular hypercellularity (asterisk), with narrow urinary spaces (arrow head), and tubular interstitial hemorrhage (arrowheads); AME 1000-I: Renal structure appeared nearly to normal form; AME 1000-II: Glomerular hypercellularity (asterisk) with narrow urinary spaces (arrow head), and interstitial Hemorrhage (arrows); Bu.F. 500-I: More or less normal renal corpuscles (arrow head), and renal tubular degenerative changes (arrow); Bu.F. 500-II: Normal renal corpuscles and tubules; Bu.F. 1000: Renal corpuscles and the renal tubules appeared nearly too normal form; Silymarin-I: Renal structure appeared nearly to normal form; Silymarin-II: Glomerular congestion and hypercellularity and narrow urinary space (arrow head), and tubular degenerative changes with pyknotic nuclei (arrow) (Scale Bar 100 µm). CdCl2: Cadmium chloride, AME: Aqueous Methanolic Extract, Bu.F: Butanol FractionBack to article page