Fig. 1From: Cellular responses to 8-methyl nonanoic acid, a degradation by-product of dihydrocapsaicin, in 3T3-L1 adipocytes8-MNA synthesis. 8-MNA was synthesized via a copper-catalyzed alkylation of Grignard reagent, followed by hydrolysis of an ester under basic conditions. (1) ethyl-6-bromohexanoate, (2) isobutyl magnesium bromide, (3) ethyl 8-methylnonanoate, and (4) 8-methyl nonanoic acidBack to article page